KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TBCC
Full Name:
Tubulin-specific chaperone C
Alias:
CFC; Tubulin folding cofactor C; Tubulin-folding cofactor C
Type:
Mass (Da):
39220
Number AA:
346
UniProt ID:
Q15814
International Prot ID:
IPI00019924
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0005874
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0051087
GO:0005515
GO:0051087
PhosphoSite+
KinaseNET
Biological Process:
GO:0007023
GO:0007023
GO:0007025
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
V
R
T
G
D
M
E
S
Q
R
D
L
S
L
V
Site 2
S23
M
E
S
Q
R
D
L
S
L
V
P
E
R
L
Q
Site 3
T63
N
S
H
F
F
V
A
T
F
A
R
E
R
A
A
Site 4
S80
E
L
L
E
R
A
E
S
V
E
R
L
E
E
A
Site 5
S89
E
R
L
E
E
A
A
S
R
L
Q
G
L
Q
K
Site 6
Y108
S
V
F
F
L
A
A
Y
D
L
R
Q
G
Q
E
Site 7
T141
K
K
R
F
A
F
K
T
R
G
K
D
A
A
S
Site 8
S148
T
R
G
K
D
A
A
S
S
T
K
V
D
A
A
Site 9
S164
G
I
P
P
A
V
E
S
I
Q
D
S
P
L
P
Site 10
S168
A
V
E
S
I
Q
D
S
P
L
P
K
K
A
E
Site 11
S181
A
E
G
D
L
G
P
S
W
V
C
G
F
S
N
Site 12
S191
C
G
F
S
N
L
E
S
Q
V
L
E
K
R
A
Site 13
S199
Q
V
L
E
K
R
A
S
E
L
H
Q
R
D
V
Site 14
T209
H
Q
R
D
V
L
L
T
E
L
S
N
C
T
V
Site 15
T215
L
T
E
L
S
N
C
T
V
R
L
Y
G
N
P
Site 16
Y219
S
N
C
T
V
R
L
Y
G
N
P
N
T
L
R
Site 17
T224
R
L
Y
G
N
P
N
T
L
R
L
T
K
A
H
Site 18
T228
N
P
N
T
L
R
L
T
K
A
H
S
C
K
L
Site 19
S265
C
Q
Q
L
R
I
H
S
T
K
D
T
R
I
F
Site 20
T269
R
I
H
S
T
K
D
T
R
I
F
L
Q
V
T
Site 21
T276
T
R
I
F
L
Q
V
T
S
R
A
I
V
E
D
Site 22
S277
R
I
F
L
Q
V
T
S
R
A
I
V
E
D
C
Site 23
Y292
S
G
I
Q
F
A
P
Y
T
W
S
Y
P
E
I
Site 24
T293
G
I
Q
F
A
P
Y
T
W
S
Y
P
E
I
D
Site 25
Y296
F
A
P
Y
T
W
S
Y
P
E
I
D
K
D
F
Site 26
S311
E
S
S
G
L
D
R
S
K
N
N
W
N
D
V
Site 27
S330
W
L
A
R
D
M
A
S
P
N
W
S
I
L
P
Site 28
S334
D
M
A
S
P
N
W
S
I
L
P
E
E
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation