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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NPTX1
Full Name:
Neuronal pentraxin-1
Alias:
Neuronal pentraxin I; NP1; NP-I
Type:
Secreted protein
Mass (Da):
47122
Number AA:
432
UniProt ID:
Q15818
International Prot ID:
IPI00220562
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030141
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0007268
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
P
A
G
R
A
A
R
T
C
A
L
L
A
L
C
Site 2
S56
G
G
A
E
E
L
R
S
S
V
L
Q
L
R
E
Site 3
S57
G
A
E
E
L
R
S
S
V
L
Q
L
R
E
T
Site 4
T64
S
V
L
Q
L
R
E
T
V
L
Q
Q
K
E
T
Site 5
S74
Q
Q
K
E
T
I
L
S
Q
K
E
T
I
R
E
Site 6
T78
T
I
L
S
Q
K
E
T
I
R
E
L
T
A
K
Site 7
T83
K
E
T
I
R
E
L
T
A
K
L
G
R
C
E
Site 8
S91
A
K
L
G
R
C
E
S
Q
S
T
L
D
P
G
Site 9
S93
L
G
R
C
E
S
Q
S
T
L
D
P
G
A
G
Site 10
T94
G
R
C
E
S
Q
S
T
L
D
P
G
A
G
E
Site 11
S113
G
G
R
K
Q
P
G
S
G
K
N
T
M
G
D
Site 12
T117
Q
P
G
S
G
K
N
T
M
G
D
L
S
R
T
Site 13
S122
K
N
T
M
G
D
L
S
R
T
P
A
A
E
T
Site 14
T124
T
M
G
D
L
S
R
T
P
A
A
E
T
L
S
Site 15
T129
S
R
T
P
A
A
E
T
L
S
Q
L
G
Q
T
Site 16
S131
T
P
A
A
E
T
L
S
Q
L
G
Q
T
L
Q
Site 17
S139
Q
L
G
Q
T
L
Q
S
L
K
T
R
L
E
N
Site 18
Y150
R
L
E
N
L
E
Q
Y
S
R
L
N
S
S
S
Site 19
S151
L
E
N
L
E
Q
Y
S
R
L
N
S
S
S
Q
Site 20
S155
E
Q
Y
S
R
L
N
S
S
S
Q
T
N
S
L
Site 21
S157
Y
S
R
L
N
S
S
S
Q
T
N
S
L
K
D
Site 22
T159
R
L
N
S
S
S
Q
T
N
S
L
K
D
L
L
Site 23
S161
N
S
S
S
Q
T
N
S
L
K
D
L
L
Q
S
Site 24
S168
S
L
K
D
L
L
Q
S
K
I
D
E
L
E
R
Site 25
T183
Q
V
L
S
R
V
N
T
L
E
E
G
K
G
G
Site 26
T195
K
G
G
P
R
N
D
T
E
E
R
V
K
I
E
Site 27
T203
E
E
R
V
K
I
E
T
A
L
T
S
L
H
Q
Site 28
S213
T
S
L
H
Q
R
I
S
E
L
E
K
G
Q
K
Site 29
T231
P
G
D
K
F
Q
L
T
F
P
L
R
T
N
Y
Site 30
Y238
T
F
P
L
R
T
N
Y
M
Y
A
K
V
K
K
Site 31
Y240
P
L
R
T
N
Y
M
Y
A
K
V
K
K
S
L
Site 32
S246
M
Y
A
K
V
K
K
S
L
P
E
M
Y
A
F
Site 33
Y273
G
V
G
T
P
F
S
Y
A
V
P
G
Q
A
N
Site 34
Y329
R
D
G
V
W
E
A
Y
Q
D
G
T
Q
G
G
Site 35
T333
W
E
A
Y
Q
D
G
T
Q
G
G
S
G
E
N
Site 36
Y344
S
G
E
N
L
A
P
Y
H
P
I
K
P
Q
G
Site 37
T361
V
L
G
Q
E
Q
D
T
L
G
G
G
F
D
A
Site 38
T387
N
I
W
D
R
K
L
T
P
G
E
V
Y
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation