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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC14A2
Full Name:
Urea transporter 2
Alias:
HUT2; Solute carrier family 14 (urea transporter) member 2; UT2; UT-A2; UTR
Type:
Membrane protein, integral; Transporter
Mass (Da):
101120
Number AA:
920
UniProt ID:
Q15849
International Prot ID:
IPI00177820
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0015204
PhosphoSite+
KinaseNET
Biological Process:
GO:0015840
Phosida
TranscriptoNet
STRING
Kinexus Products
Urea transporter 2 pan-specific antibody AB-NN355-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN355-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
D
P
H
S
S
P
L
L
P
E
P
Site 2
S7
_
M
S
D
P
H
S
S
P
L
L
P
E
P
L
Site 3
S15
P
L
L
P
E
P
L
S
S
R
Y
K
L
Y
E
Site 4
S16
L
L
P
E
P
L
S
S
R
Y
K
L
Y
E
A
Site 5
Y21
L
S
S
R
Y
K
L
Y
E
A
E
F
T
S
P
Site 6
T26
K
L
Y
E
A
E
F
T
S
P
S
W
P
S
T
Site 7
S27
L
Y
E
A
E
F
T
S
P
S
W
P
S
T
S
Site 8
S29
E
A
E
F
T
S
P
S
W
P
S
T
S
P
D
Site 9
S32
F
T
S
P
S
W
P
S
T
S
P
D
T
H
P
Site 10
T33
T
S
P
S
W
P
S
T
S
P
D
T
H
P
A
Site 11
S34
S
P
S
W
P
S
T
S
P
D
T
H
P
A
L
Site 12
T37
W
P
S
T
S
P
D
T
H
P
A
L
P
L
L
Site 13
S54
P
E
E
K
D
L
R
S
S
N
E
D
S
H
I
Site 14
S55
E
E
K
D
L
R
S
S
N
E
D
S
H
I
V
Site 15
S59
L
R
S
S
N
E
D
S
H
I
V
K
I
E
K
Site 16
S71
I
E
K
L
N
E
R
S
K
R
K
D
D
G
V
Site 17
T99
S
K
A
V
G
Y
L
T
G
D
M
K
E
Y
R
Site 18
S179
Q
D
R
S
A
I
A
S
G
L
H
G
Y
N
G
Site 19
Y202
A
F
S
E
K
L
D
Y
Y
W
W
L
L
F
P
Site 20
Y294
P
V
G
V
G
Q
V
Y
G
C
D
N
P
W
T
Site 21
Y342
A
T
P
F
E
T
I
Y
T
G
L
W
S
Y
N
Site 22
T343
T
P
F
E
T
I
Y
T
G
L
W
S
Y
N
C
Site 23
Y429
L
P
L
S
K
V
T
Y
P
E
A
N
R
I
Y
Site 24
Y436
Y
P
E
A
N
R
I
Y
Y
L
T
V
K
S
G
Site 25
Y437
P
E
A
N
R
I
Y
Y
L
T
V
K
S
G
E
Site 26
T439
A
N
R
I
Y
Y
L
T
V
K
S
G
E
E
E
Site 27
S442
I
Y
Y
L
T
V
K
S
G
E
E
E
K
A
P
Site 28
S450
G
E
E
E
K
A
P
S
G
G
G
G
E
H
P
Site 29
T459
G
G
G
E
H
P
P
T
A
G
P
K
V
E
E
Site 30
S473
E
G
S
E
A
V
L
S
K
H
R
S
V
F
H
Site 31
S477
A
V
L
S
K
H
R
S
V
F
H
I
E
W
S
Site 32
S484
S
V
F
H
I
E
W
S
S
I
R
R
R
S
K
Site 33
S485
V
F
H
I
E
W
S
S
I
R
R
R
S
K
V
Site 34
S490
W
S
S
I
R
R
R
S
K
V
F
G
K
G
E
Site 35
Y509
Q
N
K
D
P
F
P
Y
Q
Y
R
K
P
T
V
Site 36
Y511
K
D
P
F
P
Y
Q
Y
R
K
P
T
V
E
L
Site 37
T515
P
Y
Q
Y
R
K
P
T
V
E
L
L
D
L
D
Site 38
T523
V
E
L
L
D
L
D
T
M
E
E
S
S
E
I
Site 39
T534
S
S
E
I
K
V
E
T
N
I
S
K
T
S
W
Site 40
S537
I
K
V
E
T
N
I
S
K
T
S
W
I
R
S
Site 41
T539
V
E
T
N
I
S
K
T
S
W
I
R
S
S
M
Site 42
S540
E
T
N
I
S
K
T
S
W
I
R
S
S
M
A
Site 43
S544
S
K
T
S
W
I
R
S
S
M
A
A
S
G
K
Site 44
S545
K
T
S
W
I
R
S
S
M
A
A
S
G
K
R
Site 45
S549
I
R
S
S
M
A
A
S
G
K
R
V
S
K
A
Site 46
S554
A
A
S
G
K
R
V
S
K
A
L
S
Y
I
T
Site 47
S558
K
R
V
S
K
A
L
S
Y
I
T
G
E
M
K
Site 48
S575
G
E
G
L
K
D
K
S
P
V
F
Q
F
F
D
Site 49
Y664
V
F
S
D
K
G
D
Y
Y
W
W
L
L
L
P
Site 50
Y665
F
S
D
K
G
D
Y
Y
W
W
L
L
L
P
V
Site 51
Y756
P
V
G
I
G
Q
V
Y
G
C
D
N
P
W
T
Site 52
Y882
T
T
N
N
P
A
I
Y
K
L
P
L
S
K
V
Site 53
S887
A
I
Y
K
L
P
L
S
K
V
T
Y
P
E
A
Site 54
Y898
Y
P
E
A
N
R
I
Y
Y
L
S
Q
E
R
N
Site 55
Y899
P
E
A
N
R
I
Y
Y
L
S
Q
E
R
N
R
Site 56
S901
A
N
R
I
Y
Y
L
S
Q
E
R
N
R
R
A
Site 57
S909
Q
E
R
N
R
R
A
S
I
I
T
K
Y
Q
A
Site 58
Y914
R
A
S
I
I
T
K
Y
Q
A
Y
D
V
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation