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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP6AP1
Full Name:
V-type proton ATPase subunit S1
Alias:
Protein XAP-3;V-ATPase Ac45 subunit;V-ATPase S1 accessory protein;Vacuolar proton pump subunit S1
Type:
Mass (Da):
52026
Number AA:
470
UniProt ID:
Q15904
International Prot ID:
IPI00784119
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0033180
GO:0005773
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0046933
GO:0046961
PhosphoSite+
KinaseNET
Biological Process:
GO:0015986
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
M
A
A
M
A
T
A
R
V
R
M
G
P
Site 2
T69
D
T
H
E
G
H
I
T
S
D
L
Q
L
S
T
Site 3
S70
T
H
E
G
H
I
T
S
D
L
Q
L
S
T
Y
Site 4
Y77
S
D
L
Q
L
S
T
Y
L
D
P
A
L
E
L
Site 5
Y105
S
I
E
D
F
T
A
Y
G
G
V
F
G
N
K
Site 6
S115
V
F
G
N
K
Q
D
S
A
F
S
N
L
E
N
Site 7
S186
I
R
L
P
Y
T
A
S
S
G
L
M
A
P
R
Site 8
S212
Q
V
L
S
T
L
K
S
E
D
V
P
Y
T
A
Site 9
S259
P
V
I
H
P
P
V
S
Y
N
D
T
A
P
R
Site 10
T263
P
P
V
S
Y
N
D
T
A
P
R
I
L
F
W
Site 11
T286
K
D
Q
W
E
D
L
T
P
L
T
F
G
V
Q
Site 12
T289
W
E
D
L
T
P
L
T
F
G
V
Q
E
L
N
Site 13
T298
G
V
Q
E
L
N
L
T
G
S
F
W
N
D
S
Site 14
S300
Q
E
L
N
L
T
G
S
F
W
N
D
S
F
A
Site 15
S305
T
G
S
F
W
N
D
S
F
A
R
L
S
L
T
Site 16
S310
N
D
S
F
A
R
L
S
L
T
Y
E
R
L
F
Site 17
T312
S
F
A
R
L
S
L
T
Y
E
R
L
F
G
T
Site 18
T319
T
Y
E
R
L
F
G
T
T
V
T
F
K
F
I
Site 19
T320
Y
E
R
L
F
G
T
T
V
T
F
K
F
I
L
Site 20
Y332
F
I
L
A
N
R
L
Y
P
V
S
A
R
H
W
Site 21
S349
M
E
R
L
E
V
H
S
N
G
S
V
A
Y
F
Site 22
S352
L
E
V
H
S
N
G
S
V
A
Y
F
N
A
S
Site 23
Y355
H
S
N
G
S
V
A
Y
F
N
A
S
Q
V
T
Site 24
S365
A
S
Q
V
T
G
P
S
I
Y
S
F
H
C
E
Site 25
Y373
I
Y
S
F
H
C
E
Y
V
S
S
L
S
K
K
Site 26
S375
S
F
H
C
E
Y
V
S
S
L
S
K
K
G
S
Site 27
S376
F
H
C
E
Y
V
S
S
L
S
K
K
G
S
L
Site 28
S382
S
S
L
S
K
K
G
S
L
L
V
A
R
T
Q
Site 29
T388
G
S
L
L
V
A
R
T
Q
P
S
P
W
Q
M
Site 30
S391
L
V
A
R
T
Q
P
S
P
W
Q
M
M
L
Q
Site 31
S413
N
V
M
G
E
Q
F
S
Y
A
S
D
C
A
S
Site 32
S416
G
E
Q
F
S
Y
A
S
D
C
A
S
F
F
S
Site 33
S465
D
H
K
G
P
T
I
S
L
T
Q
I
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation