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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VPS72
Full Name:
Vacuolar protein sorting-associated protein 72 homolog
Alias:
Swc2; TCFL1; YL1; YL-1
Type:
Mass (Da):
40594
Number AA:
364
UniProt ID:
Q15906
International Prot ID:
IPI00020434
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043234
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
G
G
R
A
P
R
K
T
A
G
N
R
L
S
G
Site 2
S18
K
T
A
G
N
R
L
S
G
L
L
E
A
E
E
Site 3
Y30
A
E
E
E
D
E
F
Y
Q
T
T
Y
G
G
F
Site 4
T32
E
E
D
E
F
Y
Q
T
T
Y
G
G
F
T
E
Site 5
S41
Y
G
G
F
T
E
E
S
G
D
D
E
Y
Q
G
Site 6
Y46
E
E
S
G
D
D
E
Y
Q
G
D
Q
S
D
T
Site 7
S51
D
E
Y
Q
G
D
Q
S
D
T
E
D
E
V
D
Site 8
T53
Y
Q
G
D
Q
S
D
T
E
D
E
V
D
S
D
Site 9
S59
D
T
E
D
E
V
D
S
D
F
D
I
D
E
G
Site 10
S71
D
E
G
D
E
P
S
S
D
G
E
A
E
E
P
Site 11
T86
R
R
K
R
R
V
V
T
K
A
Y
K
E
P
L
Site 12
Y89
R
R
V
V
T
K
A
Y
K
E
P
L
K
S
L
Site 13
S95
A
Y
K
E
P
L
K
S
L
R
P
R
K
V
N
Site 14
T103
L
R
P
R
K
V
N
T
P
A
G
S
S
Q
K
Site 15
S127
L
E
L
Q
D
D
G
S
D
S
R
K
S
M
R
Site 16
S129
L
Q
D
D
G
S
D
S
R
K
S
M
R
Q
S
Site 17
S132
D
G
S
D
S
R
K
S
M
R
Q
S
T
A
E
Site 18
S136
S
R
K
S
M
R
Q
S
T
A
E
H
T
R
Q
Site 19
T137
R
K
S
M
R
Q
S
T
A
E
H
T
R
Q
T
Site 20
T144
T
A
E
H
T
R
Q
T
F
L
R
V
Q
E
R
Site 21
S155
V
Q
E
R
Q
G
Q
S
R
R
R
K
G
P
H
Site 22
T168
P
H
C
E
R
P
L
T
Q
E
E
L
L
R
E
Site 23
T179
L
L
R
E
A
K
I
T
E
E
L
N
L
R
S
Site 24
Y190
N
L
R
S
L
E
T
Y
E
R
L
E
A
D
K
Site 25
S242
E
G
L
D
P
A
P
S
V
S
A
L
T
P
H
Site 26
T247
A
P
S
V
S
A
L
T
P
H
A
G
T
G
P
Site 27
S262
V
N
P
P
A
R
C
S
R
T
F
I
T
F
S
Site 28
T264
P
P
A
R
C
S
R
T
F
I
T
F
S
D
D
Site 29
T267
R
C
S
R
T
F
I
T
F
S
D
D
A
T
F
Site 30
S269
S
R
T
F
I
T
F
S
D
D
A
T
F
E
E
Site 31
T273
I
T
F
S
D
D
A
T
F
E
E
W
F
P
Q
Site 32
T295
V
R
E
V
C
P
V
T
H
R
P
A
L
Y
R
Site 33
Y301
V
T
H
R
P
A
L
Y
R
D
P
V
T
D
I
Site 34
T306
A
L
Y
R
D
P
V
T
D
I
P
Y
A
T
A
Site 35
Y310
D
P
V
T
D
I
P
Y
A
T
A
R
A
F
K
Site 36
Y323
F
K
I
I
R
E
A
Y
K
K
Y
I
T
A
H
Site 37
Y326
I
R
E
A
Y
K
K
Y
I
T
A
H
G
L
P
Site 38
T335
T
A
H
G
L
P
P
T
A
S
A
L
G
P
G
Site 39
S337
H
G
L
P
P
T
A
S
A
L
G
P
G
P
P
Site 40
S352
P
P
E
P
L
P
G
S
G
P
R
A
L
R
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation