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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ETFDH
Full Name:
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
Alias:
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETFD; ETFQO; ETF-QO; ETF-ubiquinone oxidoreductase; MADD
Type:
Oxidoreductase; EC 1.5.5.1
Mass (Da):
68495
Number AA:
617
UniProt ID:
Q16134
International Prot ID:
IPI00032875
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031305
Uniprot
OncoNet
Molecular Function:
GO:0051539
GO:0050660
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0022900
GO:0033539
GO:0006979
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
P
L
C
A
I
R
W
S
S
T
S
T
V
P
R
Site 2
S37
A
I
R
W
S
S
T
S
T
V
P
R
I
T
T
Site 3
T38
I
R
W
S
S
T
S
T
V
P
R
I
T
T
H
Site 4
T43
T
S
T
V
P
R
I
T
T
H
Y
T
I
Y
P
Site 5
T44
S
T
V
P
R
I
T
T
H
Y
T
I
Y
P
R
Site 6
Y46
V
P
R
I
T
T
H
Y
T
I
Y
P
R
D
K
Site 7
T47
P
R
I
T
T
H
Y
T
I
Y
P
R
D
K
D
Site 8
Y49
I
T
T
H
Y
T
I
Y
P
R
D
K
D
K
R
Site 9
T140
E
K
G
A
P
L
N
T
P
V
T
E
D
R
F
Site 10
T151
E
D
R
F
G
I
L
T
E
K
Y
R
I
P
V
Site 11
Y172
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
L
Site 12
S181
V
R
L
G
H
L
V
S
W
M
G
E
Q
A
E
Site 13
T216
G
S
V
K
G
I
A
T
N
D
V
G
I
Q
K
Site 14
T230
K
D
G
A
P
K
A
T
F
E
R
G
L
E
L
Site 15
Y257
G
H
L
A
K
Q
L
Y
K
K
F
D
L
R
A
Site 16
T270
R
A
N
C
E
P
Q
T
Y
G
I
G
L
K
E
Site 17
Y271
A
N
C
E
P
Q
T
Y
G
I
G
L
K
E
L
Site 18
T294
K
P
G
R
V
D
H
T
V
G
W
P
L
D
R
Site 19
T303
G
W
P
L
D
R
H
T
Y
G
G
S
F
L
Y
Site 20
Y304
W
P
L
D
R
H
T
Y
G
G
S
F
L
Y
H
Site 21
S307
D
R
H
T
Y
G
G
S
F
L
Y
H
L
N
E
Site 22
Y310
T
Y
G
G
S
F
L
Y
H
L
N
E
G
E
P
Site 23
Y333
G
L
D
Y
Q
N
P
Y
L
S
P
F
R
E
F
Site 24
S335
D
Y
Q
N
P
Y
L
S
P
F
R
E
F
Q
R
Site 25
S348
Q
R
W
K
H
H
P
S
I
R
P
T
L
E
G
Site 26
T352
H
H
P
S
I
R
P
T
L
E
G
G
K
R
I
Site 27
Y361
E
G
G
K
R
I
A
Y
G
A
R
A
L
N
E
Site 28
S373
L
N
E
G
G
F
Q
S
I
P
K
L
T
F
P
Site 29
T402
P
K
I
K
G
T
H
T
A
M
K
S
G
I
L
Site 30
S406
G
T
H
T
A
M
K
S
G
I
L
A
A
E
S
Site 31
T419
E
S
I
F
N
Q
L
T
S
E
N
L
Q
S
K
Site 32
S425
L
T
S
E
N
L
Q
S
K
T
I
G
L
H
V
Site 33
Y435
I
G
L
H
V
T
E
Y
E
D
N
L
K
N
S
Site 34
Y449
S
W
V
W
K
E
L
Y
S
V
R
N
I
R
P
Site 35
T485
L
R
G
M
E
P
W
T
L
K
H
K
G
S
D
Site 36
S491
W
T
L
K
H
K
G
S
D
F
E
R
L
K
P
Site 37
T503
L
K
P
A
K
D
C
T
P
I
E
Y
P
K
P
Site 38
Y507
K
D
C
T
P
I
E
Y
P
K
P
D
G
Q
I
Site 39
S515
P
K
P
D
G
Q
I
S
F
D
L
L
S
S
V
Site 40
S525
L
L
S
S
V
A
L
S
G
T
N
H
E
H
D
Site 41
T538
H
D
Q
P
A
H
L
T
L
R
D
D
S
I
P
Site 42
S543
H
L
T
L
R
D
D
S
I
P
V
N
R
N
L
Site 43
S551
I
P
V
N
R
N
L
S
I
Y
D
G
P
E
Q
Site 44
Y553
V
N
R
N
L
S
I
Y
D
G
P
E
Q
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation