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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Septin-7
Full Name:
Septin-7
Alias:
CDC10; CDC3; SEP7; SEPT7A; Septin 7
Type:
Cell cycle regulation
Mass (Da):
50680
Number AA:
437
UniProt ID:
Q16181
International Prot ID:
IPI00033025
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0001725
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005198
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0000910
GO:0006461
GO:0007049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
V
S
A
R
S
A
A
A
E
E
R
S
Site 2
S14
S
A
A
A
E
E
R
S
V
N
S
S
T
M
V
Site 3
S18
E
E
R
S
V
N
S
S
T
M
V
A
Q
Q
K
Site 4
Y30
Q
Q
K
N
L
E
G
Y
V
G
F
A
N
L
P
Site 5
Y41
A
N
L
P
N
Q
V
Y
R
K
S
V
K
R
G
Site 6
S44
P
N
Q
V
Y
R
K
S
V
K
R
G
F
E
F
Site 7
S69
G
K
S
T
L
I
N
S
L
F
L
T
D
L
Y
Site 8
T73
L
I
N
S
L
F
L
T
D
L
Y
S
P
E
Y
Site 9
Y76
S
L
F
L
T
D
L
Y
S
P
E
Y
P
G
P
Site 10
S77
L
F
L
T
D
L
Y
S
P
E
Y
P
G
P
S
Site 11
Y80
T
D
L
Y
S
P
E
Y
P
G
P
S
H
R
I
Site 12
S84
S
P
E
Y
P
G
P
S
H
R
I
K
K
T
V
Site 13
T90
P
S
H
R
I
K
K
T
V
Q
V
E
Q
S
K
Site 14
Y133
C
W
Q
P
V
I
D
Y
I
D
S
K
F
E
D
Site 15
Y141
I
D
S
K
F
E
D
Y
L
N
A
E
S
R
V
Site 16
T198
P
L
I
A
K
A
D
T
L
T
P
E
E
C
Q
Site 17
T200
I
A
K
A
D
T
L
T
P
E
E
C
Q
Q
F
Site 18
Y223
Q
E
H
K
I
K
I
Y
E
F
P
E
T
D
D
Site 19
T228
K
I
Y
E
F
P
E
T
D
D
E
E
E
N
K
Site 20
Y267
K
R
V
R
G
R
Q
Y
P
W
G
V
A
E
V
Site 21
T301
M
Q
D
L
K
D
V
T
N
N
V
H
Y
E
N
Site 22
Y306
D
V
T
N
N
V
H
Y
E
N
Y
R
S
R
K
Site 23
Y309
N
N
V
H
Y
E
N
Y
R
S
R
K
L
A
A
Site 24
T318
S
R
K
L
A
A
V
T
Y
N
G
V
D
N
N
Site 25
Y319
R
K
L
A
A
V
T
Y
N
G
V
D
N
N
K
Site 26
T332
N
K
N
K
G
Q
L
T
K
S
P
L
A
Q
M
Site 27
S334
N
K
G
Q
L
T
K
S
P
L
A
Q
M
E
E
Site 28
S375
K
V
Q
K
L
K
D
S
E
A
E
L
Q
R
R
Site 29
S423
R
I
L
E
Q
Q
N
S
S
R
T
L
E
K
N
Site 30
S424
I
L
E
Q
Q
N
S
S
R
T
L
E
K
N
K
Site 31
T426
E
Q
Q
N
S
S
R
T
L
E
K
N
K
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation