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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC6
Full Name:
Coiled-coil domain-containing protein 6
Alias:
CDNA FLJ75411, highly similar to Homo sapiens coiled-coil domain containing 6, mRNA; D10S170; D170; DNA segment on chromosome 10 (unique) 170, H4 gene (PTC1); H4 protein
Type:
Cytoskeletal protein
Mass (Da):
53291
Number AA:
474
UniProt ID:
Q16204
International Prot ID:
IPI00871951
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005200
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
D
S
A
S
E
S
D
T
D
G
A
Site 2
S8
M
A
D
S
A
S
E
S
D
T
D
G
A
G
G
Site 3
T10
D
S
A
S
E
S
D
T
D
G
A
G
G
N
S
Site 4
S18
D
G
A
G
G
N
S
S
S
S
A
A
M
Q
S
Site 5
S19
G
A
G
G
N
S
S
S
S
A
A
M
Q
S
S
Site 6
S20
A
G
G
N
S
S
S
S
A
A
M
Q
S
S
C
Site 7
S25
S
S
S
A
A
M
Q
S
S
C
S
S
T
S
G
Site 8
S26
S
S
A
A
M
Q
S
S
C
S
S
T
S
G
G
Site 9
S28
A
A
M
Q
S
S
C
S
S
T
S
G
G
G
G
Site 10
S29
A
M
Q
S
S
C
S
S
T
S
G
G
G
G
G
Site 11
T30
M
Q
S
S
C
S
S
T
S
G
G
G
G
G
G
Site 12
S31
Q
S
S
C
S
S
T
S
G
G
G
G
G
G
G
Site 13
S46
G
G
G
G
G
G
K
S
G
G
I
V
I
S
P
Site 14
S52
K
S
G
G
I
V
I
S
P
F
R
L
E
E
L
Site 15
T60
P
F
R
L
E
E
L
T
N
R
L
A
S
L
Q
Site 16
S65
E
L
T
N
R
L
A
S
L
Q
Q
E
N
K
V
Site 17
T79
V
L
K
I
E
L
E
T
Y
K
L
K
C
K
A
Site 18
Y80
L
K
I
E
L
E
T
Y
K
L
K
C
K
A
L
Site 19
S98
N
R
D
L
R
K
A
S
V
T
I
Q
A
R
A
Site 20
T100
D
L
R
K
A
S
V
T
I
Q
A
R
A
E
Q
Site 21
S113
E
Q
E
E
E
F
I
S
N
T
L
F
K
K
I
Site 22
T115
E
E
E
F
I
S
N
T
L
F
K
K
I
Q
A
Site 23
T142
E
K
E
E
E
F
L
T
N
E
L
S
R
K
L
Site 24
S146
E
F
L
T
N
E
L
S
R
K
L
M
Q
L
Q
Site 25
T185
I
K
K
L
E
N
D
T
I
S
K
Q
L
T
L
Site 26
S187
K
L
E
N
D
T
I
S
K
Q
L
T
L
E
Q
Site 27
T191
D
T
I
S
K
Q
L
T
L
E
Q
L
R
R
E
Site 28
S240
E
K
L
D
Q
P
V
S
A
P
P
S
P
R
D
Site 29
S244
Q
P
V
S
A
P
P
S
P
R
D
I
S
M
E
Site 30
S249
P
P
S
P
R
D
I
S
M
E
I
D
S
P
E
Site 31
S254
D
I
S
M
E
I
D
S
P
E
N
M
M
R
H
Site 32
S284
R
A
A
Q
L
Q
H
S
E
K
M
A
Q
Y
L
Site 33
Y290
H
S
E
K
M
A
Q
Y
L
E
E
E
R
H
M
Site 34
S323
E
A
L
C
R
Q
L
S
E
S
E
S
S
L
E
Site 35
S325
L
C
R
Q
L
S
E
S
E
S
S
L
E
M
D
Site 36
S327
R
Q
L
S
E
S
E
S
S
L
E
M
D
D
E
Site 37
S328
Q
L
S
E
S
E
S
S
L
E
M
D
D
E
R
Site 38
Y336
L
E
M
D
D
E
R
Y
F
N
E
M
S
A
Q
Site 39
T349
A
Q
G
L
R
P
R
T
V
S
S
P
I
P
Y
Site 40
S351
G
L
R
P
R
T
V
S
S
P
I
P
Y
T
P
Site 41
S352
L
R
P
R
T
V
S
S
P
I
P
Y
T
P
S
Site 42
Y356
T
V
S
S
P
I
P
Y
T
P
S
P
S
S
S
Site 43
T357
V
S
S
P
I
P
Y
T
P
S
P
S
S
S
R
Site 44
S359
S
P
I
P
Y
T
P
S
P
S
S
S
R
P
I
Site 45
S361
I
P
Y
T
P
S
P
S
S
S
R
P
I
S
P
Site 46
S362
P
Y
T
P
S
P
S
S
S
R
P
I
S
P
G
Site 47
S363
Y
T
P
S
P
S
S
S
R
P
I
S
P
G
L
Site 48
S367
P
S
S
S
R
P
I
S
P
G
L
S
Y
A
S
Site 49
S371
R
P
I
S
P
G
L
S
Y
A
S
H
T
V
G
Site 50
Y372
P
I
S
P
G
L
S
Y
A
S
H
T
V
G
F
Site 51
S374
S
P
G
L
S
Y
A
S
H
T
V
G
F
T
P
Site 52
T376
G
L
S
Y
A
S
H
T
V
G
F
T
P
P
T
Site 53
T380
A
S
H
T
V
G
F
T
P
P
T
S
L
T
R
Site 54
S384
V
G
F
T
P
P
T
S
L
T
R
A
G
M
S
Site 55
T386
F
T
P
P
T
S
L
T
R
A
G
M
S
Y
Y
Site 56
S391
S
L
T
R
A
G
M
S
Y
Y
N
S
P
G
L
Site 57
Y392
L
T
R
A
G
M
S
Y
Y
N
S
P
G
L
H
Site 58
Y393
T
R
A
G
M
S
Y
Y
N
S
P
G
L
H
V
Site 59
S395
A
G
M
S
Y
Y
N
S
P
G
L
H
V
Q
H
Site 60
S406
H
V
Q
H
M
G
T
S
H
G
I
T
R
P
S
Site 61
T410
M
G
T
S
H
G
I
T
R
P
S
P
R
R
S
Site 62
S413
S
H
G
I
T
R
P
S
P
R
R
S
N
S
P
Site 63
S417
T
R
P
S
P
R
R
S
N
S
P
D
K
F
K
Site 64
S419
P
S
P
R
R
S
N
S
P
D
K
F
K
R
P
Site 65
T427
P
D
K
F
K
R
P
T
P
P
P
S
P
N
T
Site 66
S431
K
R
P
T
P
P
P
S
P
N
T
Q
T
P
V
Site 67
T434
T
P
P
P
S
P
N
T
Q
T
P
V
Q
P
P
Site 68
T436
P
P
S
P
N
T
Q
T
P
V
Q
P
P
P
P
Site 69
T452
P
P
P
P
M
Q
P
T
V
P
S
G
S
H
L
Site 70
S455
P
M
Q
P
T
V
P
S
G
S
H
L
A
A
Y
Site 71
S457
Q
P
T
V
P
S
G
S
H
L
A
A
Y
S
F
Site 72
S543
N
T
N
Q
T
T
F
S
I
S
V
L
L
E
S
Site 73
S554
L
L
E
S
S
C
T
S
I
P
W
L
E
P
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation