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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UAP1
Full Name:
UDP-N-acetylhexosamine pyrophosphorylase
Alias:
AGX; AGX1; AGX-1; AGX-2; Antigen X; SPAG2; Sperm-associated antigen 2; UDP-N-acetylglucosamine pyrophosphorylase; UDP-N-acteylglucosamine pyrophosphorylase 1
Type:
Carbohydrate Metabolism - amino sugar and nucleotide sugar; Transferase; EC 2.7.7.-; EC 2.7.7.23
Mass (Da):
58769
Number AA:
522
UniProt ID:
Q16222
International Prot ID:
IPI00000684
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003977
PhosphoSite+
KinaseNET
Biological Process:
GO:0006048
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
I
N
D
L
K
L
T
L
S
K
A
G
Q
E
Site 2
S11
N
D
L
K
L
T
L
S
K
A
G
Q
E
H
L
Site 3
Y34
E
A
Q
Q
V
E
L
Y
A
E
L
Q
A
M
N
Site 4
S79
V
P
R
E
V
L
G
S
A
T
R
D
Q
D
Q
Site 5
S92
D
Q
L
Q
A
W
E
S
E
G
L
F
Q
I
S
Site 6
Y120
G
T
R
L
G
V
A
Y
P
K
G
M
Y
D
V
Site 7
Y125
V
A
Y
P
K
G
M
Y
D
V
G
L
P
S
R
Site 8
T134
V
G
L
P
S
R
K
T
L
F
Q
I
Q
A
E
Site 9
Y153
L
Q
Q
V
A
E
K
Y
Y
G
N
K
C
I
I
Site 10
T170
Y
I
M
T
S
G
R
T
M
E
S
T
K
E
F
Site 11
T174
S
G
R
T
M
E
S
T
K
E
F
F
T
K
H
Site 12
Y183
E
F
F
T
K
H
K
Y
F
G
L
K
K
E
N
Site 13
S217
L
E
E
K
N
K
V
S
M
A
P
D
G
N
G
Site 14
Y227
P
D
G
N
G
G
L
Y
R
A
L
A
A
Q
N
Site 15
T283
G
A
K
V
V
E
K
T
N
P
T
E
P
V
G
Site 16
Y299
V
C
R
V
D
G
V
Y
Q
V
V
E
Y
S
E
Site 17
Y304
G
V
Y
Q
V
V
E
Y
S
E
I
S
L
A
T
Site 18
S317
A
T
A
Q
K
R
S
S
D
G
R
L
L
F
N
Site 19
Y345
L
R
D
V
V
N
V
Y
E
P
Q
L
Q
H
H
Site 20
Y360
V
A
Q
K
K
I
P
Y
V
D
T
Q
G
Q
L
Site 21
T363
K
K
I
P
Y
V
D
T
Q
G
Q
L
I
K
P
Site 22
S404
V
L
R
E
D
E
F
S
P
L
K
N
A
D
S
Site 23
S411
S
P
L
K
N
A
D
S
Q
N
G
K
D
N
P
Site 24
T419
Q
N
G
K
D
N
P
T
T
A
R
H
A
L
M
Site 25
T420
N
G
K
D
N
P
T
T
A
R
H
A
L
M
S
Site 26
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Site 27
S454
R
L
P
A
I
P
R
S
A
T
N
G
K
S
E
Site 28
T456
P
A
I
P
R
S
A
T
N
G
K
S
E
T
I
Site 29
S460
R
S
A
T
N
G
K
S
E
T
I
T
A
D
V
Site 30
T464
N
G
K
S
E
T
I
T
A
D
V
N
H
N
L
Site 31
S496
Y
A
G
E
G
L
E
S
Y
V
A
D
K
E
F
Site 32
Y497
A
G
E
G
L
E
S
Y
V
A
D
K
E
F
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation