PhosphoNET

           
Protein Info 
   
Short Name:  E2F4
Full Name:  Transcription factor E2F4
Alias:  E2F-4
Type: 
Mass (Da):  43960
Number AA:  413
UniProt ID:  Q16254
International Prot ID:  IPI00292880
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005667     Uniprot OncoNet
Molecular Function:  GO:0019904  GO:0003700  GO:0008134 PhosphoSite+ KinaseNET
Biological Process:  GO:0006350     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T14QAPPPPGTPSRHEKS
Site 2S16PPPPGTPSRHEKSLG
Site 3S21TPSRHEKSLGLLTTK
Site 4T49DLKLAADTLAVRQKR
Site 5Y59VRQKRRIYDITNVLE
Site 6T62KRRIYDITNVLEGIG
Site 7S75IGLIEKKSKNSIQWK
Site 8T129QQSIRNVTEDVQNSC
Site 9Y179GLNGQKKYQIHLKSV
Site 10S185KYQIHLKSVSGPIEV
Site 11S218PPEDLLQSPSAVSTP
Site 12S220EDLLQSPSAVSTPPP
Site 13S223LQSPSAVSTPPPLPK
Site 14T224QSPSAVSTPPPLPKP
Site 15S236PKPALAQSQEASRPN
Site 16S240LAQSQEASRPNSPQL
Site 17S244QEASRPNSPQLTPTA
Site 18T248RPNSPQLTPTAVPGS
Site 19T250NSPQLTPTAVPGSAE
Site 20S271PAAEITVSGGPGTDS
Site 21T276TVSGGPGTDSKDSGE
Site 22S278SGGPGTDSKDSGELS
Site 23S281PGTDSKDSGELSSLP
Site 24S285SKDSGELSSLPLGPT
Site 25S286KDSGELSSLPLGPTT
Site 26T293SLPLGPTTLDTRPLQ
Site 27T296LGPTTLDTRPLQSSA
Site 28S302DTRPLQSSALLDSSS
Site 29S307QSSALLDSSSSSSSS
Site 30S308SSALLDSSSSSSSSS
Site 31S309SALLDSSSSSSSSSS
Site 32S310ALLDSSSSSSSSSSS
Site 33S311LLDSSSSSSSSSSSS
Site 34S312LDSSSSSSSSSSSSS
Site 35S313DSSSSSSSSSSSSSN
Site 36S314SSSSSSSSSSSSSNS
Site 37S315SSSSSSSSSSSSNSN
Site 38S316SSSSSSSSSSSNSNS
Site 39S317SSSSSSSSSSNSNSS
Site 40S318SSSSSSSSSNSNSSS
Site 41S319SSSSSSSSNSNSSSS
Site 42S321SSSSSSNSNSSSSSG
Site 43S323SSSSNSNSSSSSGPN
Site 44S324SSSNSNSSSSSGPNP
Site 45S325SSNSNSSSSSGPNPS
Site 46S326SNSNSSSSSGPNPST
Site 47S327NSNSSSSSGPNPSTS
Site 48S332SSSGPNPSTSFEPIK
Site 49S334SGPNPSTSFEPIKAD
Site 50T343EPIKADPTGVLELPK
Site 51S353LELPKELSEIFDPTR
Site 52T359LSEIFDPTRECMSSE
Site 53S365PTRECMSSELLEELM
Site 54S384FAPLLRLSPPPGDHD
Site 55Y392PPPGDHDYIYNLDES
Site 56Y394PGDHDYIYNLDESEG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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