KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KCNA10
Full Name:
Potassium voltage-gated channel subfamily A member 10
Alias:
Voltage-gated potassium channel subunit Kv1.8
Type:
Mass (Da):
57785
Number AA:
511
UniProt ID:
Q16322
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
A
L
V
N
F
D
N
S
D
E
I
Q
E
E
P
Site 2
Y28
E
I
Q
E
E
P
G
Y
A
T
D
F
D
S
T
Site 3
T30
Q
E
E
P
G
Y
A
T
D
F
D
S
T
S
P
Site 4
S34
G
Y
A
T
D
F
D
S
T
S
P
K
G
R
P
Site 5
S36
A
T
D
F
D
S
T
S
P
K
G
R
P
G
G
Site 6
S44
P
K
G
R
P
G
G
S
S
F
S
N
G
K
I
Site 7
S45
K
G
R
P
G
G
S
S
F
S
N
G
K
I
L
Site 8
S47
R
P
G
G
S
S
F
S
N
G
K
I
L
I
S
Site 9
S56
G
K
I
L
I
S
E
S
T
N
H
E
T
A
F
Site 10
S64
T
N
H
E
T
A
F
S
K
L
P
G
D
Y
A
Site 11
Y70
F
S
K
L
P
G
D
Y
A
D
P
P
G
P
E
Site 12
T99
I
A
G
L
R
F
E
T
Q
L
R
T
L
S
Q
Site 13
T103
R
F
E
T
Q
L
R
T
L
S
Q
F
P
E
T
Site 14
S105
E
T
Q
L
R
T
L
S
Q
F
P
E
T
L
L
Site 15
Y129
F
D
S
M
R
N
E
Y
F
F
D
R
N
R
P
Site 16
Y143
P
S
F
D
G
I
L
Y
Y
Y
Q
S
G
G
K
Site 17
Y144
S
F
D
G
I
L
Y
Y
Y
Q
S
G
G
K
I
Site 18
Y145
F
D
G
I
L
Y
Y
Y
Q
S
G
G
K
I
R
Site 19
S147
G
I
L
Y
Y
Y
Q
S
G
G
K
I
R
R
P
Site 20
S167
D
I
F
A
D
E
I
S
F
Y
E
L
G
S
E
Site 21
Y169
F
A
D
E
I
S
F
Y
E
L
G
S
E
A
M
Site 22
T191
G
F
I
K
D
P
E
T
L
L
P
T
N
D
I
Site 23
Y208
Q
F
W
L
L
F
E
Y
P
E
S
S
S
A
A
Site 24
S258
R
D
P
N
L
N
M
S
K
T
V
L
S
Q
T
Site 25
T260
P
N
L
N
M
S
K
T
V
L
S
Q
T
M
F
Site 26
S263
N
M
S
K
T
V
L
S
Q
T
M
F
T
D
P
Site 27
T265
S
K
T
V
L
S
Q
T
M
F
T
D
P
F
F
Site 28
S330
L
V
Q
E
T
E
P
S
A
Q
Q
N
M
S
L
Site 29
S355
V
F
R
I
F
K
L
S
R
H
S
K
G
L
Q
Site 30
S358
I
F
K
L
S
R
H
S
K
G
L
Q
I
L
G
Site 31
S403
A
E
V
D
E
P
E
S
H
F
S
S
I
P
D
Site 32
S406
D
E
P
E
S
H
F
S
S
I
P
D
G
F
W
Site 33
T431
Y
G
D
M
C
P
T
T
P
G
G
K
I
V
G
Site 34
Y462
V
I
V
S
N
F
N
Y
F
Y
H
R
E
T
E
Site 35
Y464
V
S
N
F
N
Y
F
Y
H
R
E
T
E
N
E
Site 36
T468
N
Y
F
Y
H
R
E
T
E
N
E
E
K
Q
N
Site 37
S486
E
I
E
R
I
L
N
S
V
G
S
R
M
G
S
Site 38
S489
R
I
L
N
S
V
G
S
R
M
G
S
T
D
S
Site 39
S493
S
V
G
S
R
M
G
S
T
D
S
L
N
K
T
Site 40
S496
S
R
M
G
S
T
D
S
L
N
K
T
N
G
G
Site 41
T500
S
T
D
S
L
N
K
T
N
G
G
C
S
T
E
Site 42
S505
N
K
T
N
G
G
C
S
T
E
K
S
R
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation