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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRY1
Full Name:
Cryptochrome-1
Alias:
Cryptochrome 1; cryptochrome 1 (photolyase-like); PHLL1; Photolyase
Type:
DNA binding protein; Lyase
Mass (Da):
66395
Number AA:
586
UniProt ID:
Q16526
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003913
GO:0008020
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0007623
GO:0018298
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
L
D
P
W
F
A
G
S
S
N
V
G
I
N
R
Site 2
S71
A
N
L
R
K
L
N
S
R
L
F
V
I
R
G
Site 3
S102
K
L
S
I
E
Y
D
S
E
P
F
G
K
E
R
Site 4
Y133
V
R
I
S
H
T
L
Y
D
L
D
K
I
I
E
Site 5
T149
N
G
G
Q
P
P
L
T
Y
K
R
F
Q
T
L
Site 6
Y150
G
G
Q
P
P
L
T
Y
K
R
F
Q
T
L
I
Site 7
T155
L
T
Y
K
R
F
Q
T
L
I
S
K
M
E
P
Site 8
S158
K
R
F
Q
T
L
I
S
K
M
E
P
L
E
I
Site 9
T180
E
V
I
E
K
C
T
T
P
L
S
D
D
H
D
Site 10
S183
E
K
C
T
T
P
L
S
D
D
H
D
E
K
Y
Site 11
Y190
S
D
D
H
D
E
K
Y
G
V
P
S
L
E
E
Site 12
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Site 13
S206
G
F
D
T
D
G
L
S
S
A
V
W
P
G
G
Site 14
S207
F
D
T
D
G
L
S
S
A
V
W
P
G
G
E
Site 15
S243
R
P
R
M
N
A
N
S
L
L
A
S
P
T
G
Site 16
S247
N
A
N
S
L
L
A
S
P
T
G
L
S
P
Y
Site 17
T249
N
S
L
L
A
S
P
T
G
L
S
P
Y
L
R
Site 18
Y266
C
L
S
C
R
L
F
Y
F
K
L
T
D
L
Y
Site 19
Y273
Y
F
K
L
T
D
L
Y
K
K
V
K
K
N
S
Site 20
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Site 21
S281
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
G
Site 22
S285
K
N
S
S
P
P
L
S
L
Y
G
Q
L
L
W
Site 23
Y287
S
S
P
P
L
S
L
Y
G
Q
L
L
W
R
E
Site 24
T301
E
F
F
Y
T
A
A
T
N
N
P
R
F
D
K
Site 25
T422
P
V
G
F
G
R
R
T
D
P
N
G
D
Y
I
Site 26
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Site 27
Y432
N
G
D
Y
I
R
R
Y
L
P
V
L
R
G
F
Site 28
Y443
L
R
G
F
P
A
K
Y
I
Y
D
P
W
N
A
Site 29
Y466
K
C
L
I
G
V
N
Y
P
K
P
M
V
N
H
Site 30
Y488
I
E
R
M
K
Q
I
Y
Q
Q
L
S
R
Y
R
Site 31
S492
K
Q
I
Y
Q
Q
L
S
R
Y
R
G
L
G
L
Site 32
S502
R
G
L
G
L
L
A
S
V
P
S
N
P
N
G
Site 33
S505
G
L
L
A
S
V
P
S
N
P
N
G
N
G
G
Site 34
S525
A
E
N
I
P
G
C
S
S
S
G
S
C
S
Q
Site 35
S526
E
N
I
P
G
C
S
S
S
G
S
C
S
Q
G
Site 36
S527
N
I
P
G
C
S
S
S
G
S
C
S
Q
G
S
Site 37
S529
P
G
C
S
S
S
G
S
C
S
Q
G
S
G
I
Site 38
S531
C
S
S
S
G
S
C
S
Q
G
S
G
I
L
H
Site 39
S534
S
G
S
C
S
Q
G
S
G
I
L
H
Y
A
H
Site 40
Y539
Q
G
S
G
I
L
H
Y
A
H
G
D
S
Q
Q
Site 41
S544
L
H
Y
A
H
G
D
S
Q
Q
T
H
L
L
K
Site 42
S555
H
L
L
K
Q
G
R
S
S
M
G
T
G
L
S
Site 43
S556
L
L
K
Q
G
R
S
S
M
G
T
G
L
S
G
Site 44
T559
Q
G
R
S
S
M
G
T
G
L
S
G
G
K
R
Site 45
S562
S
S
M
G
T
G
L
S
G
G
K
R
P
S
Q
Site 46
S568
L
S
G
G
K
R
P
S
Q
E
E
D
T
Q
S
Site 47
T573
R
P
S
Q
E
E
D
T
Q
S
I
G
P
K
V
Site 48
S575
S
Q
E
E
D
T
Q
S
I
G
P
K
V
Q
R
Site 49
S584
G
P
K
V
Q
R
Q
S
T
N
_
_
_
_
_
Site 50
T585
P
K
V
Q
R
Q
S
T
N
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation