PhosphoNET

           
Protein Info 
   
Short Name:  ZNF74
Full Name:  Zinc finger protein 74
Alias:  Zinc finger protein 520;hZNF7
Type: 
Mass (Da):  72207
Number AA:  644
UniProt ID:  Q16587
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T11PAPEPEKTALSSQDP
Site 2S14EPEKTALSSQDPALS
Site 3S15PEKTALSSQDPALSL
Site 4S21SSQDPALSLKENLED
Site 5S39WGLPEARSKESVSFK
Site 6S42PEARSKESVSFKDVA
Site 7S44ARSKESVSFKDVAVD
Site 8T53KDVAVDFTQEEWGQL
Site 9S62EEWGQLDSPQRALYR
Site 10Y68DSPQRALYRDVMLEN
Site 11Y76RDVMLENYQNLLALG
Site 12S103ERGEEPWSMQREVPR
Site 13S123WELKAVPSQQQGICK
Site 14S159QAGALQRSQAAPGRR
Site 15T167QAAPGRRTCHGLGRP
Site 16S260GKAFRQSSSLTLHRR
Site 17S261KAFRQSSSLTLHRRW
Site 18S317KAFSCHSSLNVHQRI
Site 19S344EKAFSCSSLLSMHLR
Site 20T522IMHQRIHTGEKPYKC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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