KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ECM1
Full Name:
Extracellular matrix protein 1
Alias:
Secretory component p85
Type:
Mass (Da):
60674
Number AA:
540
UniProt ID:
Q16610
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
A
A
S
E
G
G
F
T
A
T
G
Q
R
Q
L
Site 2
Y43
E
H
F
Q
E
V
G
Y
A
A
P
P
S
P
P
Site 3
S48
V
G
Y
A
A
P
P
S
P
P
L
S
R
S
L
Site 4
S52
A
P
P
S
P
P
L
S
R
S
L
P
M
D
H
Site 5
S54
P
S
P
P
L
S
R
S
L
P
M
D
H
P
D
Site 6
S62
L
P
M
D
H
P
D
S
S
Q
H
G
P
P
F
Site 7
S63
P
M
D
H
P
D
S
S
Q
H
G
P
P
F
E
Site 8
S73
G
P
P
F
E
G
Q
S
Q
V
Q
P
P
P
S
Site 9
S80
S
Q
V
Q
P
P
P
S
Q
E
A
T
P
L
Q
Site 10
T84
P
P
P
S
Q
E
A
T
P
L
Q
Q
E
K
L
Site 11
T130
P
N
E
Q
K
E
G
T
P
A
P
F
G
D
Q
Site 12
S138
P
A
P
F
G
D
Q
S
H
P
E
P
E
S
W
Site 13
S173
G
F
P
P
G
R
P
S
P
D
N
L
N
Q
I
Site 14
Y190
P
N
R
Q
H
V
V
Y
G
P
W
N
L
P
Q
Site 15
S198
G
P
W
N
L
P
Q
S
S
Y
S
H
L
T
R
Site 16
S199
P
W
N
L
P
Q
S
S
Y
S
H
L
T
R
Q
Site 17
Y217
L
N
F
L
E
I
G
Y
S
R
C
C
H
C
R
Site 18
S268
R
Q
G
E
A
R
F
S
C
F
Q
E
E
A
P
Site 19
Y279
E
E
A
P
Q
P
H
Y
Q
L
R
A
C
P
S
Site 20
S286
Y
Q
L
R
A
C
P
S
H
Q
P
D
I
S
S
Site 21
S292
P
S
H
Q
P
D
I
S
S
G
L
E
L
P
F
Site 22
S293
S
H
Q
P
D
I
S
S
G
L
E
L
P
F
P
Site 23
T305
P
F
P
P
G
V
P
T
L
D
N
I
K
N
I
Site 24
S320
C
H
L
R
R
F
R
S
V
P
R
N
L
P
A
Site 25
T328
V
P
R
N
L
P
A
T
D
P
L
Q
R
E
L
Site 26
Y369
W
E
D
T
L
D
K
Y
C
D
R
E
Y
A
V
Site 27
Y374
D
K
Y
C
D
R
E
Y
A
V
K
T
H
H
H
Site 28
S389
L
C
C
R
H
P
P
S
P
T
R
D
E
C
F
Site 29
Y402
C
F
A
R
R
A
P
Y
P
N
Y
D
R
D
I
Site 30
Y405
R
R
A
P
Y
P
N
Y
D
R
D
I
L
T
I
Site 31
T411
N
Y
D
R
D
I
L
T
I
D
I
G
R
V
T
Site 32
T418
T
I
D
I
G
R
V
T
P
N
L
M
G
H
L
Site 33
T433
C
G
N
Q
R
V
L
T
K
H
K
H
I
P
G
Site 34
T467
C
A
E
E
E
K
L
T
F
I
N
D
L
C
G
Site 35
Y488
R
D
P
A
L
C
C
Y
L
S
P
G
D
E
Q
Site 36
S490
P
A
L
C
C
Y
L
S
P
G
D
E
Q
V
N
Site 37
T514
V
A
L
V
S
G
D
T
E
N
A
K
G
Q
G
Site 38
S525
K
G
Q
G
E
Q
G
S
T
G
G
T
N
I
S
Site 39
T529
E
Q
G
S
T
G
G
T
N
I
S
S
T
S
E
Site 40
S532
S
T
G
G
T
N
I
S
S
T
S
E
P
K
E
Site 41
S533
T
G
G
T
N
I
S
S
T
S
E
P
K
E
E
Site 42
T534
G
G
T
N
I
S
S
T
S
E
P
K
E
E
_
Site 43
S535
G
T
N
I
S
S
T
S
E
P
K
E
E
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation