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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NF-E2
Full Name:
Transcription factor NF-E2 45 kDa subunit
Alias:
Leucine zipper protein NF-E2;Nuclear factor, erythroid-derived 2 45 kDa subunit;p45 NF-E2
Type:
Transcription protein
Mass (Da):
41473
Number AA:
373
UniProt ID:
Q16621
International Prot ID:
IPI00003367
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0050699
GO:0047485
GO:0046983
PhosphoSite+
KinaseNET
Biological Process:
GO:0008015
GO:0007599
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
R
N
R
V
I
Q
L
S
T
S
E
L
G
E
M
Site 2
S19
R
V
I
Q
L
S
T
S
E
L
G
E
M
E
L
Site 3
T27
E
L
G
E
M
E
L
T
W
Q
E
I
M
S
I
Site 4
S44
L
Q
G
L
N
A
P
S
E
P
S
F
E
P
Q
Site 5
S47
L
N
A
P
S
E
P
S
F
E
P
Q
A
P
A
Site 6
Y56
E
P
Q
A
P
A
P
Y
L
G
P
P
P
P
T
Site 7
T64
L
G
P
P
P
P
T
T
Y
C
P
C
S
I
H
Site 8
Y65
G
P
P
P
P
T
T
Y
C
P
C
S
I
H
P
Site 9
S74
P
C
S
I
H
P
D
S
G
F
P
L
P
P
P
Site 10
Y83
F
P
L
P
P
P
P
Y
E
L
P
A
S
T
S
Site 11
S88
P
P
Y
E
L
P
A
S
T
S
H
V
P
D
P
Site 12
S90
Y
E
L
P
A
S
T
S
H
V
P
D
P
P
Y
Site 13
Y97
S
H
V
P
D
P
P
Y
S
Y
G
N
M
A
I
Site 14
S144
K
P
Q
E
D
P
E
S
D
S
G
L
S
L
N
Site 15
S146
Q
E
D
P
E
S
D
S
G
L
S
L
N
Y
S
Site 16
S149
P
E
S
D
S
G
L
S
L
N
Y
S
D
A
E
Site 17
S153
S
G
L
S
L
N
Y
S
D
A
E
S
L
E
L
Site 18
S157
L
N
Y
S
D
A
E
S
L
E
L
E
G
T
E
Site 19
T163
E
S
L
E
L
E
G
T
E
A
G
R
R
R
S
Site 20
S170
T
E
A
G
R
R
R
S
E
Y
V
E
M
Y
P
Site 21
Y172
A
G
R
R
R
S
E
Y
V
E
M
Y
P
V
E
Site 22
Y176
R
S
E
Y
V
E
M
Y
P
V
E
Y
P
Y
S
Site 23
Y180
V
E
M
Y
P
V
E
Y
P
Y
S
L
M
P
N
Site 24
Y182
M
Y
P
V
E
Y
P
Y
S
L
M
P
N
S
L
Site 25
S183
Y
P
V
E
Y
P
Y
S
L
M
P
N
S
L
A
Site 26
S188
P
Y
S
L
M
P
N
S
L
A
H
S
N
Y
T
Site 27
S192
M
P
N
S
L
A
H
S
N
Y
T
L
P
A
A
Site 28
Y194
N
S
L
A
H
S
N
Y
T
L
P
A
A
E
T
Site 29
S208
T
P
L
A
L
E
P
S
S
G
P
V
R
A
K
Site 30
S209
P
L
A
L
E
P
S
S
G
P
V
R
A
K
P
Site 31
T217
G
P
V
R
A
K
P
T
A
R
G
E
A
G
S
Site 32
S224
T
A
R
G
E
A
G
S
R
D
E
R
R
A
L
Site 33
Y257
F
N
E
L
L
A
R
Y
P
L
T
E
S
Q
L
Site 34
S262
A
R
Y
P
L
T
E
S
Q
L
A
L
V
R
D
Site 35
T302
E
R
E
L
E
R
L
T
N
E
R
E
R
L
L
Site 36
T318
A
R
G
E
A
D
R
T
L
E
V
M
R
Q
Q
Site 37
Y330
R
Q
Q
L
T
E
L
Y
R
D
I
F
Q
H
L
Site 38
S341
F
Q
H
L
R
D
E
S
G
N
S
Y
S
P
E
Site 39
S344
L
R
D
E
S
G
N
S
Y
S
P
E
E
Y
A
Site 40
Y345
R
D
E
S
G
N
S
Y
S
P
E
E
Y
A
L
Site 41
S346
D
E
S
G
N
S
Y
S
P
E
E
Y
A
L
Q
Site 42
T367
I
F
L
V
P
R
G
T
K
M
E
A
T
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation