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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OCLN
Full Name:
Occludin
Alias:
Occludin; Tight junction protein occludin TM4 minus
Type:
Adhesion
Mass (Da):
59144
Number AA:
522
UniProt ID:
Q16625
International Prot ID:
IPI00003373
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005923
Uniprot
OncoNet
Molecular Function:
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0006461
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
S
R
P
L
E
S
P
P
P
Y
R
P
D
Site 2
Y12
P
L
E
S
P
P
P
Y
R
P
D
E
F
K
P
Site 3
S25
K
P
N
H
Y
A
P
S
N
D
I
Y
G
G
E
Site 4
Y29
Y
A
P
S
N
D
I
Y
G
G
E
M
H
V
R
Site 5
S40
M
H
V
R
P
M
L
S
Q
P
A
Y
S
F
Y
Site 6
Y44
P
M
L
S
Q
P
A
Y
S
F
Y
P
E
D
E
Site 7
S45
M
L
S
Q
P
A
Y
S
F
Y
P
E
D
E
I
Site 8
Y47
S
Q
P
A
Y
S
F
Y
P
E
D
E
I
L
H
Site 9
Y56
E
D
E
I
L
H
F
Y
K
W
T
S
P
P
G
Site 10
T59
I
L
H
F
Y
K
W
T
S
P
P
G
V
I
R
Site 11
Y93
T
L
A
W
D
R
G
Y
G
T
S
L
L
G
G
Site 12
S96
W
D
R
G
Y
G
T
S
L
L
G
G
S
V
G
Site 13
Y106
G
G
S
V
G
Y
P
Y
G
G
S
G
F
G
S
Site 14
S109
V
G
Y
P
Y
G
G
S
G
F
G
S
Y
G
S
Site 15
S113
Y
G
G
S
G
F
G
S
Y
G
S
G
Y
G
Y
Site 16
Y114
G
G
S
G
F
G
S
Y
G
S
G
Y
G
Y
G
Site 17
S116
S
G
F
G
S
Y
G
S
G
Y
G
Y
G
Y
G
Site 18
Y118
F
G
S
Y
G
S
G
Y
G
Y
G
Y
G
Y
G
Site 19
Y120
S
Y
G
S
G
Y
G
Y
G
Y
G
Y
G
Y
G
Site 20
Y122
G
S
G
Y
G
Y
G
Y
G
Y
G
Y
G
Y
G
Site 21
Y124
G
Y
G
Y
G
Y
G
Y
G
Y
G
Y
G
G
Y
Site 22
Y126
G
Y
G
Y
G
Y
G
Y
G
Y
G
G
Y
T
D
Site 23
Y131
Y
G
Y
G
Y
G
G
Y
T
D
P
R
A
A
K
Site 24
S163
F
V
T
S
V
I
R
S
E
M
S
R
T
R
R
Site 25
S166
S
V
I
R
S
E
M
S
R
T
R
R
Y
Y
L
Site 26
T168
I
R
S
E
M
S
R
T
R
R
Y
Y
L
S
V
Site 27
Y171
E
M
S
R
T
R
R
Y
Y
L
S
V
I
I
V
Site 28
T267
I
I
F
F
A
V
K
T
R
R
K
M
D
R
Y
Site 29
Y274
T
R
R
K
M
D
R
Y
D
K
S
N
I
L
W
Site 30
Y287
L
W
D
K
E
H
I
Y
D
E
Q
P
P
N
V
Site 31
T305
V
K
N
V
S
A
G
T
Q
D
V
P
S
P
P
Site 32
S310
A
G
T
Q
D
V
P
S
P
P
S
D
Y
V
E
Site 33
S313
Q
D
V
P
S
P
P
S
D
Y
V
E
R
V
D
Site 34
Y315
V
P
S
P
P
S
D
Y
V
E
R
V
D
S
P
Site 35
S321
D
Y
V
E
R
V
D
S
P
M
A
Y
S
S
N
Site 36
Y325
R
V
D
S
P
M
A
Y
S
S
N
G
K
V
N
Site 37
S326
V
D
S
P
M
A
Y
S
S
N
G
K
V
N
D
Site 38
S327
D
S
P
M
A
Y
S
S
N
G
K
V
N
D
K
Site 39
Y337
K
V
N
D
K
R
F
Y
P
E
S
S
Y
K
S
Site 40
S340
D
K
R
F
Y
P
E
S
S
Y
K
S
T
P
V
Site 41
S341
K
R
F
Y
P
E
S
S
Y
K
S
T
P
V
P
Site 42
Y342
R
F
Y
P
E
S
S
Y
K
S
T
P
V
P
E
Site 43
S344
Y
P
E
S
S
Y
K
S
T
P
V
P
E
V
V
Site 44
T345
P
E
S
S
Y
K
S
T
P
V
P
E
V
V
Q
Site 45
T357
V
V
Q
E
L
P
L
T
S
P
V
D
D
F
R
Site 46
S358
V
Q
E
L
P
L
T
S
P
V
D
D
F
R
Q
Site 47
Y368
D
D
F
R
Q
P
R
Y
S
S
G
G
N
F
E
Site 48
S369
D
F
R
Q
P
R
Y
S
S
G
G
N
F
E
T
Site 49
S370
F
R
Q
P
R
Y
S
S
G
G
N
F
E
T
P
Site 50
T376
S
S
G
G
N
F
E
T
P
S
K
R
A
P
A
Site 51
S378
G
G
N
F
E
T
P
S
K
R
A
P
A
K
G
Site 52
S390
A
K
G
R
A
G
R
S
K
R
T
E
Q
D
H
Site 53
T393
R
A
G
R
S
K
R
T
E
Q
D
H
Y
E
T
Site 54
Y398
K
R
T
E
Q
D
H
Y
E
T
D
Y
T
T
G
Site 55
T400
T
E
Q
D
H
Y
E
T
D
Y
T
T
G
G
E
Site 56
Y402
Q
D
H
Y
E
T
D
Y
T
T
G
G
E
S
C
Site 57
T403
D
H
Y
E
T
D
Y
T
T
G
G
E
S
C
D
Site 58
T404
H
Y
E
T
D
Y
T
T
G
G
E
S
C
D
E
Site 59
S408
D
Y
T
T
G
G
E
S
C
D
E
L
E
E
D
Site 60
Y420
E
E
D
W
I
R
E
Y
P
P
I
T
S
D
Q
Site 61
T424
I
R
E
Y
P
P
I
T
S
D
Q
Q
R
Q
L
Site 62
Y432
S
D
Q
Q
R
Q
L
Y
K
R
N
F
D
T
G
Site 63
T438
L
Y
K
R
N
F
D
T
G
L
Q
E
Y
K
S
Site 64
Y443
F
D
T
G
L
Q
E
Y
K
S
L
Q
S
E
L
Site 65
S445
T
G
L
Q
E
Y
K
S
L
Q
S
E
L
D
E
Site 66
Y467
L
D
K
E
L
D
D
Y
R
E
E
S
E
E
Y
Site 67
S471
L
D
D
Y
R
E
E
S
E
E
Y
M
A
A
A
Site 68
Y474
Y
R
E
E
S
E
E
Y
M
A
A
A
D
E
Y
Site 69
Y481
Y
M
A
A
A
D
E
Y
N
R
L
K
Q
V
K
Site 70
S490
R
L
K
Q
V
K
G
S
A
D
Y
K
S
K
K
Site 71
Y493
Q
V
K
G
S
A
D
Y
K
S
K
K
N
H
C
Site 72
S495
K
G
S
A
D
Y
K
S
K
K
N
H
C
K
Q
Site 73
S505
N
H
C
K
Q
L
K
S
K
L
S
H
I
K
K
Site 74
S508
K
Q
L
K
S
K
L
S
H
I
K
K
M
V
G
Site 75
Y517
I
K
K
M
V
G
D
Y
D
R
Q
K
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation