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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMN1
Full Name:
Survival motor neuron protein
Alias:
BCD541; Component of gems 1; Gemin1; SMA; SMA@; SMA1; SMA2; SMA3; SMN, SMNT; SMN2; SMNC; SMNT; Survival of motor neuron 1, telomeric
Type:
RNA binding protein; RNA processing
Mass (Da):
31849
Number AA:
294
UniProt ID:
Q16637
International Prot ID:
IPI00003394
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015030
GO:0005829
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
GO:0000387
GO:0000245
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
M
S
S
G
G
S
G
G
G
Site 2
S5
_
_
_
M
A
M
S
S
G
G
S
G
G
G
V
Site 3
S8
M
A
M
S
S
G
G
S
G
G
G
V
P
E
Q
Site 4
S18
G
V
P
E
Q
E
D
S
V
L
F
R
R
G
T
Site 5
T25
S
V
L
F
R
R
G
T
G
Q
S
D
D
S
D
Site 6
S28
F
R
R
G
T
G
Q
S
D
D
S
D
I
W
D
Site 7
S31
G
T
G
Q
S
D
D
S
D
I
W
D
D
T
A
Site 8
T37
D
S
D
I
W
D
D
T
A
L
I
K
A
Y
D
Site 9
Y43
D
T
A
L
I
K
A
Y
D
K
A
V
A
S
F
Site 10
S49
A
Y
D
K
A
V
A
S
F
K
H
A
L
K
N
Site 11
T68
E
T
S
G
K
P
K
T
T
P
K
R
K
P
A
Site 12
T69
T
S
G
K
P
K
T
T
P
K
R
K
P
A
K
Site 13
S80
K
P
A
K
K
N
K
S
Q
K
K
N
T
A
A
Site 14
T85
N
K
S
Q
K
K
N
T
A
A
S
L
Q
Q
W
Site 15
S88
Q
K
K
N
T
A
A
S
L
Q
Q
W
K
V
G
Site 16
Y109
W
S
E
D
G
C
I
Y
P
A
T
I
A
S
I
Site 17
Y127
R
E
T
C
V
V
V
Y
T
G
Y
G
N
R
E
Site 18
Y130
C
V
V
V
Y
T
G
Y
G
N
R
E
E
Q
N
Site 19
S139
N
R
E
E
Q
N
L
S
D
L
L
S
P
I
C
Site 20
S163
A
Q
E
N
E
N
E
S
Q
V
S
T
D
E
S
Site 21
S166
N
E
N
E
S
Q
V
S
T
D
E
S
E
N
S
Site 22
T167
E
N
E
S
Q
V
S
T
D
E
S
E
N
S
R
Site 23
S170
S
Q
V
S
T
D
E
S
E
N
S
R
S
P
G
Site 24
S173
S
T
D
E
S
E
N
S
R
S
P
G
N
K
S
Site 25
S175
D
E
S
E
N
S
R
S
P
G
N
K
S
D
N
Site 26
S180
S
R
S
P
G
N
K
S
D
N
I
K
P
K
S
Site 27
S187
S
D
N
I
K
P
K
S
A
P
W
N
S
F
L
Site 28
S192
P
K
S
A
P
W
N
S
F
L
P
P
P
P
P
Site 29
S230
P
P
P
P
H
L
L
S
C
W
L
P
P
F
P
Site 30
S253
P
P
P
I
C
P
D
S
L
D
D
A
D
A
L
Site 31
Y268
G
S
M
L
I
S
W
Y
M
S
G
Y
H
T
G
Site 32
Y276
M
S
G
Y
H
T
G
Y
Y
M
G
F
R
Q
N
Site 33
Y277
S
G
Y
H
T
G
Y
Y
M
G
F
R
Q
N
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation