PhosphoNET

           
Protein Info 
   
Short Name:  SMN1
Full Name:  Survival motor neuron protein
Alias:  BCD541; Component of gems 1; Gemin1; SMA; SMA@; SMA1; SMA2; SMA3; SMN, SMNT; SMN2; SMNC; SMNT; Survival of motor neuron 1, telomeric
Type:  RNA binding protein; RNA processing
Mass (Da):  31849
Number AA:  294
UniProt ID:  Q16637
International Prot ID:  IPI00003394
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0015030  GO:0005829  GO:0005681 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0005515  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0008219  GO:0000387  GO:0000245 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S4____MAMSSGGSGGG
Site 2S5___MAMSSGGSGGGV
Site 3S8MAMSSGGSGGGVPEQ
Site 4S18GVPEQEDSVLFRRGT
Site 5T25SVLFRRGTGQSDDSD
Site 6S28FRRGTGQSDDSDIWD
Site 7S31GTGQSDDSDIWDDTA
Site 8T37DSDIWDDTALIKAYD
Site 9Y43DTALIKAYDKAVASF
Site 10S49AYDKAVASFKHALKN
Site 11T68ETSGKPKTTPKRKPA
Site 12T69TSGKPKTTPKRKPAK
Site 13S80KPAKKNKSQKKNTAA
Site 14T85NKSQKKNTAASLQQW
Site 15S88QKKNTAASLQQWKVG
Site 16Y109WSEDGCIYPATIASI
Site 17Y127RETCVVVYTGYGNRE
Site 18Y130CVVVYTGYGNREEQN
Site 19S139NREEQNLSDLLSPIC
Site 20S163AQENENESQVSTDES
Site 21S166NENESQVSTDESENS
Site 22T167ENESQVSTDESENSR
Site 23S170SQVSTDESENSRSPG
Site 24S173STDESENSRSPGNKS
Site 25S175DESENSRSPGNKSDN
Site 26S180SRSPGNKSDNIKPKS
Site 27S187SDNIKPKSAPWNSFL
Site 28S192PKSAPWNSFLPPPPP
Site 29S230PPPPHLLSCWLPPFP
Site 30S253PPPICPDSLDDADAL
Site 31Y268GSMLISWYMSGYHTG
Site 32Y276MSGYHTGYYMGFRQN
Site 33Y277SGYHTGYYMGFRQNQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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