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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NRF1
Full Name:
Nuclear respiratory factor 1
Alias:
Alpha palindromic-binding protein
Type:
Mass (Da):
53541
Number AA:
503
UniProt ID:
Q16656
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
Q
Q
V
H
V
A
T
Y
T
E
H
S
M
L
S
Site 2
S39
Y
T
E
H
S
M
L
S
A
D
E
D
S
P
S
Site 3
S44
M
L
S
A
D
E
D
S
P
S
S
P
E
D
T
Site 4
S46
S
A
D
E
D
S
P
S
S
P
E
D
T
S
Y
Site 5
S47
A
D
E
D
S
P
S
S
P
E
D
T
S
Y
D
Site 6
T51
S
P
S
S
P
E
D
T
S
Y
D
D
S
D
I
Site 7
S52
P
S
S
P
E
D
T
S
Y
D
D
S
D
I
L
Site 8
Y53
S
S
P
E
D
T
S
Y
D
D
S
D
I
L
N
Site 9
S56
E
D
T
S
Y
D
D
S
D
I
L
N
S
T
A
Site 10
S99
K
R
P
H
V
F
E
S
N
P
S
I
R
K
R
Site 11
S102
H
V
F
E
S
N
P
S
I
R
K
R
Q
Q
T
Site 12
T109
S
I
R
K
R
Q
Q
T
R
L
L
R
K
L
R
Site 13
T118
L
L
R
K
L
R
A
T
L
D
E
Y
T
T
R
Site 14
Y122
L
R
A
T
L
D
E
Y
T
T
R
V
G
Q
Q
Site 15
T123
R
A
T
L
D
E
Y
T
T
R
V
G
Q
Q
A
Site 16
Y159
L
E
N
V
V
R
K
Y
K
S
M
I
L
E
D
Site 17
S161
N
V
V
R
K
Y
K
S
M
I
L
E
D
L
E
Site 18
S183
P
A
P
Q
E
V
N
S
E
L
P
P
L
T
I
Site 19
T201
P
V
S
V
D
K
M
T
Q
A
Q
L
R
A
F
Site 20
Y215
F
I
P
E
M
L
K
Y
S
T
G
R
G
K
P
Site 21
S216
I
P
E
M
L
K
Y
S
T
G
R
G
K
P
G
Site 22
T217
P
E
M
L
K
Y
S
T
G
R
G
K
P
G
W
Site 23
S245
I
P
W
A
N
V
R
S
D
V
R
T
E
E
Q
Site 24
T249
N
V
R
S
D
V
R
T
E
E
Q
K
Q
R
V
Site 25
S257
E
E
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
Site 26
T259
Q
K
Q
R
V
S
W
T
Q
A
L
R
T
I
V
Site 27
Y270
R
T
I
V
K
N
C
Y
K
Q
H
G
R
E
D
Site 28
Y280
H
G
R
E
D
L
L
Y
A
F
E
D
Q
Q
T
Site 29
T287
Y
A
F
E
D
Q
Q
T
Q
T
Q
A
T
A
T
Site 30
T309
P
S
Q
T
V
V
Q
T
F
S
N
P
D
G
T
Site 31
S311
Q
T
V
V
Q
T
F
S
N
P
D
G
T
V
S
Site 32
S318
S
N
P
D
G
T
V
S
L
I
Q
V
G
T
G
Site 33
T342
S
E
L
P
T
T
V
T
V
A
Q
V
N
Y
S
Site 34
T372
G
G
E
M
T
I
Q
T
T
Q
A
S
E
A
T
Site 35
S465
M
Y
Q
T
V
V
T
S
L
A
Q
G
N
G
P
Site 36
S485
A
P
V
T
T
R
I
S
D
S
A
V
T
M
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation