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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP1B1
Full Name:
Cytochrome P450 1B1
Alias:
CP1B; CP1B1; CYPIB1; Cytochrome P450, family 1, subfamily B, polypeptide 1; EC 1.14.14.1; GLC3A
Type:
EC 1.14.14.1; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - tryptophan; Oxidoreductase
Mass (Da):
60846
Number AA:
543
UniProt ID:
Q16678
International Prot ID:
IPI00003451
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005789
GO:0019898
GO:0005792
Uniprot
OncoNet
Molecular Function:
GO:0070330
GO:0009055
GO:0020037
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
T
S
L
S
P
N
D
P
W
P
L
Site 2
S17
P
W
P
L
N
P
L
S
I
Q
Q
T
T
L
L
Site 3
S49
Q
R
R
R
Q
L
R
S
A
P
P
G
P
F
A
Site 4
S73
V
G
Q
A
A
H
L
S
F
A
R
L
A
R
R
Site 5
Y81
F
A
R
L
A
R
R
Y
G
D
V
F
Q
I
R
Site 6
S131
R
V
V
S
G
G
R
S
M
A
F
G
H
Y
S
Site 7
T157
S
M
M
R
N
F
F
T
R
Q
P
R
S
R
Q
Site 8
S162
F
F
T
R
Q
P
R
S
R
Q
V
L
E
G
H
Site 9
S226
P
E
F
R
E
L
L
S
H
N
E
E
F
G
R
Site 10
T234
H
N
E
E
F
G
R
T
V
G
A
G
S
L
V
Site 11
Y249
D
V
M
P
W
L
Q
Y
F
P
N
P
V
R
T
Site 12
T256
Y
F
P
N
P
V
R
T
V
F
R
E
F
E
Q
Site 13
S269
E
Q
L
N
R
N
F
S
N
F
I
L
D
K
F
Site 14
S282
K
F
L
R
H
C
E
S
L
R
P
G
A
A
P
Site 15
S308
E
K
K
A
A
G
D
S
H
G
G
G
A
R
L
Site 16
Y380
G
D
Q
P
N
L
P
Y
V
L
A
F
L
Y
E
Site 17
Y412
A
N
T
S
V
L
G
Y
H
I
P
K
D
T
V
Site 18
T457
G
L
I
N
K
D
L
T
S
R
V
M
I
F
S
Site 19
Y507
P
A
K
M
N
F
S
Y
G
L
T
I
K
P
K
Site 20
T510
M
N
F
S
Y
G
L
T
I
K
P
K
S
F
K
Site 21
T521
K
S
F
K
V
N
V
T
L
R
E
S
M
E
L
Site 22
S531
E
S
M
E
L
L
D
S
A
V
Q
N
L
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation