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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cyp2a5
Full Name:
Cytochrome P450 2A13
Alias:
Cpa6; Cpa7; Cpad; Cyp2a; Cyp2a13; Cyp2a3; Cypiia7; Cytochrome p450, family 2, subfamily a, polypeptide 13; EC 1.14.14.1; P450c2a; P450-iia4; P450pb
Type:
Membrane, Endoplasmic reticulum, Microsome, Endoplasmic reticulum membrane protein
Mass (Da):
56688
Number AA:
494
UniProt ID:
Q16696
International Prot ID:
IPI00003480
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005789
GO:0019898
GO:0005792
Uniprot
OncoNet
Molecular Function:
GO:0070330
GO:0008389
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
S
V
W
R
Q
R
K
S
R
G
K
L
P
P
G
Site 2
T38
G
K
L
P
P
G
P
T
P
L
P
F
I
G
N
Site 3
Y46
P
L
P
F
I
G
N
Y
L
Q
L
N
T
E
Q
Site 4
S57
N
T
E
Q
M
Y
N
S
L
M
K
I
S
E
R
Site 5
S62
Y
N
S
L
M
K
I
S
E
R
Y
G
P
V
F
Site 6
S99
V
D
Q
A
E
E
F
S
G
R
G
E
Q
A
T
Site 7
T106
S
G
R
G
E
Q
A
T
F
D
W
L
F
K
G
Site 8
S119
K
G
Y
G
V
A
F
S
N
G
E
R
A
K
Q
Site 9
S131
A
K
Q
L
R
R
F
S
I
A
T
L
R
G
F
Site 10
T163
L
I
D
A
L
R
G
T
H
G
A
N
I
D
P
Site 11
T171
H
G
A
N
I
D
P
T
F
F
L
S
R
T
V
Site 12
Y193
V
F
G
D
R
F
D
Y
E
D
K
E
F
L
S
Site 13
S200
Y
E
D
K
E
F
L
S
L
L
R
M
M
L
G
Site 14
S215
S
F
Q
F
T
A
T
S
T
G
Q
L
Y
E
M
Site 15
S224
G
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
Site 16
S225
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
G
Site 17
T258
K
V
E
H
N
Q
R
T
L
D
P
N
S
P
R
Site 18
S263
Q
R
T
L
D
P
N
S
P
R
D
F
I
D
S
Site 19
S270
S
P
R
D
F
I
D
S
F
L
I
R
M
Q
E
Site 20
Y287
K
N
P
N
T
E
F
Y
L
K
N
L
V
M
T
Site 21
Y351
E
D
R
A
K
M
P
Y
T
E
A
V
I
H
E
Site 22
T352
D
R
A
K
M
P
Y
T
E
A
V
I
H
E
I
Site 23
T378
A
H
R
V
N
K
D
T
K
F
R
D
F
F
L
Site 24
S406
L
R
D
P
R
F
F
S
N
P
R
D
F
N
P
Site 25
S426
K
K
G
Q
F
K
K
S
D
A
F
V
P
F
S
Site 26
S464
M
Q
N
F
R
F
K
S
P
Q
S
P
K
D
I
Site 27
S467
F
R
F
K
S
P
Q
S
P
K
D
I
D
V
S
Site 28
S474
S
P
K
D
I
D
V
S
P
K
H
V
G
F
A
Site 29
T482
P
K
H
V
G
F
A
T
I
P
R
N
Y
T
M
Site 30
Y487
F
A
T
I
P
R
N
Y
T
M
S
F
L
P
R
Site 31
T488
A
T
I
P
R
N
Y
T
M
S
F
L
P
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation