PhosphoNET

           
Protein Info 
   
Short Name:  QPCT
Full Name:  Glutaminyl-peptide cyclotransferase
Alias:  Glutaminyl cyclase;Glutaminyl-tRNA cyclotransferase;Glutamyl cyclase
Type: 
Mass (Da):  40877
Number AA:  361
UniProt ID:  Q16769
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S30PWASRGVSPSASAWP
Site 2S32ASRGVSPSASAWPEE
Site 3S34RGVSPSASAWPEEKN
Site 4Y42AWPEEKNYHQPAILN
Site 5Y78QPLLIERYPGSPGSY
Site 6S81LIERYPGSPGSYAAR
Site 7S84RYPGSPGSYAARQHI
Site 8Y85YPGSPGSYAARQHIM
Site 9T108DWVLEIDTFLSQTPY
Site 10S111LEIDTFLSQTPYGYR
Site 11T113IDTFLSQTPYGYRSF
Site 12Y115TFLSQTPYGYRSFSN
Site 13Y117LSQTPYGYRSFSNII
Site 14S119QTPYGYRSFSNIIST
Site 15S121PYGYRSFSNIISTLN
Site 16S125RSFSNIISTLNPTAK
Site 17T126SFSNIISTLNPTAKR
Site 18T130IISTLNPTAKRHLVL
Site 19Y141HLVLACHYDSKYFSH
Site 20S180ALDKKLLSLKTVSDS
Site 21T183KKLLSLKTVSDSKPD
Site 22S185LLSLKTVSDSKPDLS
Site 23S187SLKTVSDSKPDLSLQ
Site 24S192SDSKPDLSLQLIFFD
Site 25S208EEAFLHWSPQDSLYG
Site 26S212LHWSPQDSLYGSRHL
Site 27Y214WSPQDSLYGSRHLAA
Site 28S216PQDSLYGSRHLAAKM
Site 29T226LAAKMASTPHPPGAR
Site 30T235HPPGARGTSQLHGMD
Site 31S236PPGARGTSQLHGMDL
Site 32T256LIGAPNPTFPNFFPN
Site 33S288LGLLKDHSLEGRYFQ
Site 34Y293DHSLEGRYFQNYSYG
Site 35Y297EGRYFQNYSYGGVIQ
Site 36Y299RYFQNYSYGGVIQDD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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