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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCBL1
Full Name:
Kynurenine--oxoglutarate transaminase 1
Alias:
Cysteine conjugate-beta lyase; Cysteine conjugate-beta lyase, cytoplasmic; Cysteine-S-conjugate beta-lyase; Cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase); Cytoplasmic cysteine conjugate-beta lyase; EC 2.6.1.64; EC 2.6.1.7; EC 4.4.1.13; Glutamine transaminase K; Glutamine-phenylpyruvate aminotransferase; Glutamine--phenylpyruvate transaminase; GTK; KAT1; KATI; Kyneurenine aminotransferase; Kynurenine aminotransferase I; Kynurenine--oxoglutarate transaminase I
Type:
Lyase; EC 2.6.1.7; EC 4.4.1.13; Transferase; EC 2.6.1.64
Mass (Da):
47875
Number AA:
422
UniProt ID:
Q16773
International Prot ID:
IPI00002523
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005829
GO:0044424
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0005488
GO:0008483
PhosphoSite+
KinaseNET
Biological Process:
GO:0006519
GO:0006575
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
R
R
L
D
G
I
D
Y
N
P
W
V
E
F
V
Site 2
Y63
G
D
F
M
L
N
Q
Y
T
K
T
F
G
Y
P
Site 3
T66
M
L
N
Q
Y
T
K
T
F
G
Y
P
P
L
T
Site 4
Y69
Q
Y
T
K
T
F
G
Y
P
P
L
T
K
I
L
Site 5
S143
G
G
R
P
V
F
V
S
L
K
P
G
P
I
Q
Site 6
S157
Q
N
G
E
L
G
S
S
S
N
W
Q
L
D
P
Site 7
S158
N
G
E
L
G
S
S
S
N
W
Q
L
D
P
M
Site 8
T172
M
E
L
A
G
K
F
T
S
R
T
K
A
L
V
Site 9
T175
A
G
K
F
T
S
R
T
K
A
L
V
L
N
T
Site 10
T182
T
K
A
L
V
L
N
T
P
N
N
P
L
G
K
Site 11
S192
N
P
L
G
K
V
F
S
R
E
E
L
E
L
V
Site 12
S201
E
E
L
E
L
V
A
S
L
C
Q
Q
H
D
V
Site 13
S228
Y
D
G
H
Q
H
I
S
I
A
S
L
P
G
M
Site 14
T241
G
M
W
E
R
T
L
T
I
G
S
A
G
K
T
Site 15
T248
T
I
G
S
A
G
K
T
F
S
A
T
G
W
K
Site 16
S250
G
S
A
G
K
T
F
S
A
T
G
W
K
V
G
Site 17
S284
V
F
H
C
P
T
Q
S
Q
A
A
V
A
E
S
Site 18
S291
S
Q
A
A
V
A
E
S
F
E
R
E
Q
L
L
Site 19
S303
Q
L
L
F
R
Q
P
S
S
Y
F
V
Q
F
P
Site 20
S304
L
L
F
R
Q
P
S
S
Y
F
V
Q
F
P
Q
Site 21
Y305
L
F
R
Q
P
S
S
Y
F
V
Q
F
P
Q
A
Site 22
S323
C
R
D
H
M
I
R
S
L
Q
S
V
G
L
K
Site 23
Y362
P
G
A
V
D
E
P
Y
D
R
R
F
V
K
W
Site 24
Y385
A
I
P
V
S
I
F
Y
S
V
P
H
Q
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation