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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DUSP7
Full Name:
Dual specificity protein phosphatase 7
Alias:
Dual specificity protein phosphatase PYST2; DUS7; DUS7_HUMAN; EC 3.1.3.16; EC 3.1.3.48; PYST2
Type:
Protein phosphatase, dual specificity
Mass (Da):
40551
Number AA:
368
UniProt ID:
Q16829
International Prot ID:
IPI00394738
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0017017
GO:0005515
GO:0004722
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Dual specificity protein phosphatase 7 pan-specific antibody AB-NP041-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NP041-1#Dual specificity protein phosphatase 7 pan-specific antibody AB-NP041-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NP041-2#Dual specificity protein phosphatase 7 pan-specific antibody AB-NP041-3#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NP041-3#Dual specificity protein phosphatase 7 (M1-M14, human) peptide - Powder PE-01BBD90#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BBD90#Dual specificity protein phosphatase 7 (C391-P405, human) peptide - Powder PE-01BBE95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BBE95#Dual specificity protein phosphatase 7 (P405-T409, human) peptide - Powder PE-01BBF99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BBF99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
R
P
H
E
L
F
E
S
S
H
I
E
T
A
I
Site 2
S35
P
H
E
L
F
E
S
S
H
I
E
T
A
I
N
Site 3
S62
K
G
N
L
P
I
R
S
I
I
P
N
H
A
D
Site 4
T75
A
D
K
E
R
F
A
T
R
C
K
A
A
T
V
Site 5
T89
V
L
L
Y
D
E
A
T
A
E
W
Q
P
E
P
Site 6
Y118
R
D
D
G
C
Q
A
Y
Y
L
Q
G
G
F
N
Site 7
Y119
D
D
G
C
Q
A
Y
Y
L
Q
G
G
F
N
K
Site 8
T137
E
Y
S
E
H
C
E
T
N
V
D
S
S
S
S
Site 9
S141
H
C
E
T
N
V
D
S
S
S
S
P
S
S
S
Site 10
S142
C
E
T
N
V
D
S
S
S
S
P
S
S
S
P
Site 11
S143
E
T
N
V
D
S
S
S
S
P
S
S
S
P
P
Site 12
S144
T
N
V
D
S
S
S
S
P
S
S
S
P
P
T
Site 13
S146
V
D
S
S
S
S
P
S
S
S
P
P
T
S
V
Site 14
S147
D
S
S
S
S
P
S
S
S
P
P
T
S
V
L
Site 15
S148
S
S
S
S
P
S
S
S
P
P
T
S
V
L
G
Site 16
T151
S
P
S
S
S
P
P
T
S
V
L
G
L
G
G
Site 17
S152
P
S
S
S
P
P
T
S
V
L
G
L
G
G
L
Site 18
S162
G
L
G
G
L
R
I
S
S
D
C
S
D
G
E
Site 19
S163
L
G
G
L
R
I
S
S
D
C
S
D
G
E
S
Site 20
S166
L
R
I
S
S
D
C
S
D
G
E
S
D
R
E
Site 21
S170
S
D
C
S
D
G
E
S
D
R
E
L
P
S
S
Site 22
S176
E
S
D
R
E
L
P
S
S
A
T
E
S
D
G
Site 23
S177
S
D
R
E
L
P
S
S
A
T
E
S
D
G
S
Site 24
T179
R
E
L
P
S
S
A
T
E
S
D
G
S
P
V
Site 25
S181
L
P
S
S
A
T
E
S
D
G
S
P
V
P
S
Site 26
S184
S
A
T
E
S
D
G
S
P
V
P
S
S
Q
P
Site 27
S188
S
D
G
S
P
V
P
S
S
Q
P
A
F
P
V
Site 28
S189
D
G
S
P
V
P
S
S
Q
P
A
F
P
V
Q
Site 29
T210
L
G
C
A
K
D
S
T
N
L
D
V
L
G
K
Site 30
Y222
L
G
K
Y
G
I
K
Y
I
L
N
V
T
P
N
Site 31
Y242
E
H
G
G
E
F
T
Y
K
Q
I
P
I
S
D
Site 32
S264
Q
F
F
P
E
A
I
S
F
I
D
E
A
R
S
Site 33
Y307
N
L
S
L
N
D
A
Y
D
F
V
K
R
K
K
Site 34
S315
D
F
V
K
R
K
K
S
N
I
S
P
N
F
N
Site 35
S318
K
R
K
K
S
N
I
S
P
N
F
N
F
M
G
Site 36
T333
Q
L
L
D
F
E
R
T
L
G
L
S
S
P
C
Site 37
S337
F
E
R
T
L
G
L
S
S
P
C
D
N
H
A
Site 38
S338
E
R
T
L
G
L
S
S
P
C
D
N
H
A
S
Site 39
S346
P
C
D
N
H
A
S
S
E
Q
L
Y
F
S
T
Site 40
Y350
H
A
S
S
E
Q
L
Y
F
S
T
P
T
N
H
Site 41
T353
S
E
Q
L
Y
F
S
T
P
T
N
H
N
L
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation