PhosphoNET

           
Protein Info 
   
Short Name:  LTC4S
Full Name:  Leukotriene C4 synthase
Alias:  EC 4.4.1.20; Leukotriene-C; LTC4 synthase
Type: 
Mass (Da):  16567
Number AA:  150
UniProt ID:  Q16873
International Prot ID:  IPI00004509
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0016021  GO:0005792 Uniprot OncoNet
Molecular Function:  GO:0008047  GO:0004464  GO:0008289 PhosphoSite+ KinaseNET
Biological Process:  GO:0019370     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S36ARRAFRVSPPLTTGP
Site 2T40FRVSPPLTTGPPEFE
Site 3T41RVSPPLTTGPPEFER
Site 4Y50PPEFERVYRAQVNCS
Site 5Y93YLFARLRYFQGYARS
Site 6Y97RLRYFQGYARSAQLR
Site 7Y109QLRLAPLYASARALW
Site 8S111RLAPLYASARALWLL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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