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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TPD52L1
Full Name:
Tumor protein D53
Alias:
D53; HD53; MGC8556; TPD52L2; TPD53; Tumor protein D52-like 1
Type:
Adapter/scaffold protein
Mass (Da):
22449
Number AA:
204
UniProt ID:
Q16890
International Prot ID:
IPI00383670
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0048471
GO:0044424
GO:0044444
Uniprot
OncoNet
Molecular Function:
GO:0008656
GO:0046982
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0006309
GO:0000086
GO:0006917
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
T
D
E
D
A
V
A
S
A
D
F
S
S
M
L
Site 2
S28
A
V
A
S
A
D
F
S
S
M
L
S
E
E
E
Site 3
S29
V
A
S
A
D
F
S
S
M
L
S
E
E
E
K
Site 4
S32
A
D
F
S
S
M
L
S
E
E
E
K
E
E
L
Site 5
T51
V
Q
L
E
D
E
I
T
T
L
R
Q
V
L
S
Site 6
S86
L
K
Q
N
F
S
K
S
W
H
D
M
Q
T
T
Site 7
Y96
D
M
Q
T
T
T
A
Y
K
K
T
H
E
T
L
Site 8
T99
T
T
T
A
Y
K
K
T
H
E
T
L
S
H
A
Site 9
T102
A
Y
K
K
T
H
E
T
L
S
H
A
G
Q
K
Site 10
S104
K
K
T
H
E
T
L
S
H
A
G
Q
K
A
T
Site 11
S122
S
N
V
G
T
A
I
S
K
K
F
G
D
M
S
Site 12
S129
S
K
K
F
G
D
M
S
Y
S
I
R
H
S
I
Site 13
Y130
K
K
F
G
D
M
S
Y
S
I
R
H
S
I
S
Site 14
S131
K
F
G
D
M
S
Y
S
I
R
H
S
I
S
M
Site 15
S135
M
S
Y
S
I
R
H
S
I
S
M
P
A
M
R
Site 16
S137
Y
S
I
R
H
S
I
S
M
P
A
M
R
N
S
Site 17
S144
S
M
P
A
M
R
N
S
P
T
F
K
S
F
E
Site 18
T146
P
A
M
R
N
S
P
T
F
K
S
F
E
E
R
Site 19
S149
R
N
S
P
T
F
K
S
F
E
E
R
V
E
T
Site 20
T156
S
F
E
E
R
V
E
T
T
V
T
S
L
K
T
Site 21
T157
F
E
E
R
V
E
T
T
V
T
S
L
K
T
K
Site 22
T159
E
R
V
E
T
T
V
T
S
L
K
T
K
V
G
Site 23
S160
R
V
E
T
T
V
T
S
L
K
T
K
V
G
G
Site 24
T163
T
T
V
T
S
L
K
T
K
V
G
G
T
N
P
Site 25
S174
G
T
N
P
N
G
G
S
F
E
E
V
L
S
S
Site 26
S180
G
S
F
E
E
V
L
S
S
T
A
H
A
S
A
Site 27
S181
S
F
E
E
V
L
S
S
T
A
H
A
S
A
Q
Site 28
S186
L
S
S
T
A
H
A
S
A
Q
S
L
A
G
G
Site 29
S189
T
A
H
A
S
A
Q
S
L
A
G
G
S
R
R
Site 30
T197
L
A
G
G
S
R
R
T
K
E
E
E
L
Q
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation