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Updated November 2019
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Protein Info
Short Name:
Zfp827
Full Name:
Zinc finger protein 827
Alias:
Znf827
Type:
Mass (Da):
119147
Number AA:
1081
UniProt ID:
Q17R98
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
Q
P
K
R
L
P
S
H
V
S
R
Q
E
E
Site 2
S17
K
R
L
P
S
H
V
S
R
Q
E
E
A
E
G
Site 3
S27
E
E
A
E
G
E
L
S
E
G
E
H
W
Y
G
Site 4
Y33
L
S
E
G
E
H
W
Y
G
N
S
S
E
T
P
Site 5
S37
E
H
W
Y
G
N
S
S
E
T
P
S
E
A
S
Site 6
T39
W
Y
G
N
S
S
E
T
P
S
E
A
S
Y
G
Site 7
S41
G
N
S
S
E
T
P
S
E
A
S
Y
G
E
V
Site 8
Y45
E
T
P
S
E
A
S
Y
G
E
V
Q
E
N
Y
Site 9
Y52
Y
G
E
V
Q
E
N
Y
K
L
S
L
E
D
R
Site 10
S64
E
D
R
I
Q
E
Q
S
T
S
P
D
T
S
L
Site 11
S66
R
I
Q
E
Q
S
T
S
P
D
T
S
L
G
S
Site 12
T69
E
Q
S
T
S
P
D
T
S
L
G
S
T
T
P
Site 13
S70
Q
S
T
S
P
D
T
S
L
G
S
T
T
P
S
Site 14
S73
S
P
D
T
S
L
G
S
T
T
P
S
S
H
T
Site 15
T74
P
D
T
S
L
G
S
T
T
P
S
S
H
T
L
Site 16
T75
D
T
S
L
G
S
T
T
P
S
S
H
T
L
E
Site 17
S77
S
L
G
S
T
T
P
S
S
H
T
L
E
L
V
Site 18
S94
D
S
E
V
L
R
D
S
L
Q
C
Q
D
H
L
Site 19
S102
L
Q
C
Q
D
H
L
S
P
G
V
S
S
L
C
Site 20
S106
D
H
L
S
P
G
V
S
S
L
C
D
D
D
P
Site 21
S107
H
L
S
P
G
V
S
S
L
C
D
D
D
P
G
Site 22
S115
L
C
D
D
D
P
G
S
N
K
P
L
S
S
N
Site 23
S120
P
G
S
N
K
P
L
S
S
N
L
R
R
L
L
Site 24
S121
G
S
N
K
P
L
S
S
N
L
R
R
L
L
E
Site 25
S131
R
R
L
L
E
A
G
S
L
K
L
D
A
A
A
Site 26
S146
T
A
N
G
R
V
E
S
P
V
N
V
G
S
N
Site 27
S152
E
S
P
V
N
V
G
S
N
L
S
F
S
P
P
Site 28
S155
V
N
V
G
S
N
L
S
F
S
P
P
S
H
H
Site 29
S157
V
G
S
N
L
S
F
S
P
P
S
H
H
A
Q
Site 30
S160
N
L
S
F
S
P
P
S
H
H
A
Q
Q
L
S
Site 31
S167
S
H
H
A
Q
Q
L
S
V
L
A
R
K
L
A
Site 32
Y183
K
Q
E
Q
N
D
Q
Y
T
P
S
N
R
F
I
Site 33
S200
Q
G
K
W
L
P
N
S
T
T
T
C
S
L
S
Site 34
T201
G
K
W
L
P
N
S
T
T
T
C
S
L
S
P
Site 35
T202
K
W
L
P
N
S
T
T
T
C
S
L
S
P
D
Site 36
T203
W
L
P
N
S
T
T
T
C
S
L
S
P
D
S
Site 37
S205
P
N
S
T
T
T
C
S
L
S
P
D
S
A
I
Site 38
S207
S
T
T
T
C
S
L
S
P
D
S
A
I
L
K
Site 39
S210
T
C
S
L
S
P
D
S
A
I
L
K
L
K
A
Site 40
S227
N
A
V
L
Q
D
K
S
L
T
R
T
E
E
T
Site 41
T231
Q
D
K
S
L
T
R
T
E
E
T
M
R
F
E
Site 42
T234
S
L
T
R
T
E
E
T
M
R
F
E
S
F
S
Site 43
S239
E
E
T
M
R
F
E
S
F
S
S
P
F
S
S
Site 44
S241
T
M
R
F
E
S
F
S
S
P
F
S
S
Q
S
Site 45
S242
M
R
F
E
S
F
S
S
P
F
S
S
Q
S
A
Site 46
S245
E
S
F
S
S
P
F
S
S
Q
S
A
S
S
T
Site 47
S246
S
F
S
S
P
F
S
S
Q
S
A
S
S
T
L
Site 48
S248
S
S
P
F
S
S
Q
S
A
S
S
T
L
A
A
Site 49
S250
P
F
S
S
Q
S
A
S
S
T
L
A
A
L
S
Site 50
T252
S
S
Q
S
A
S
S
T
L
A
A
L
S
K
K
Site 51
S257
S
S
T
L
A
A
L
S
K
K
V
S
E
R
S
Site 52
S261
A
A
L
S
K
K
V
S
E
R
S
L
T
P
G
Site 53
S264
S
K
K
V
S
E
R
S
L
T
P
G
Q
E
H
Site 54
T266
K
V
S
E
R
S
L
T
P
G
Q
E
H
P
P
Site 55
S276
Q
E
H
P
P
P
A
S
S
F
L
S
L
A
S
Site 56
S277
E
H
P
P
P
A
S
S
F
L
S
L
A
S
M
Site 57
S307
G
S
L
L
A
E
K
S
S
L
L
P
E
D
P
Site 58
S308
S
L
L
A
E
K
S
S
L
L
P
E
D
P
L
Site 59
S320
D
P
L
P
P
P
P
S
E
K
K
P
E
K
V
Site 60
T328
E
K
K
P
E
K
V
T
P
P
P
P
P
P
P
Site 61
S345
P
P
P
P
P
P
Q
S
L
E
L
L
L
L
P
Site 62
S359
P
V
P
K
G
R
V
S
K
P
S
N
S
A
S
Site 63
S362
K
G
R
V
S
K
P
S
N
S
A
S
E
E
E
Site 64
S364
R
V
S
K
P
S
N
S
A
S
E
E
E
S
G
Site 65
S366
S
K
P
S
N
S
A
S
E
E
E
S
G
K
P
Site 66
S370
N
S
A
S
E
E
E
S
G
K
P
F
Q
C
P
Site 67
Y388
L
V
I
K
R
K
S
Y
W
K
R
H
M
V
I
Site 68
T441
Q
C
Q
L
C
P
F
T
S
S
R
H
F
S
L
Site 69
S442
C
Q
L
C
P
F
T
S
S
R
H
F
S
L
K
Site 70
S443
Q
L
C
P
F
T
S
S
R
H
F
S
L
K
L
Site 71
S447
F
T
S
S
R
H
F
S
L
K
L
H
M
R
C
Site 72
S477
P
D
P
D
V
K
G
S
P
H
L
S
D
S
A
Site 73
S481
V
K
G
S
P
H
L
S
D
S
A
C
L
G
Q
Site 74
S483
G
S
P
H
L
S
D
S
A
C
L
G
Q
Q
R
Site 75
T495
Q
Q
R
E
G
G
G
T
E
L
V
G
T
M
M
Site 76
T500
G
G
T
E
L
V
G
T
M
M
T
S
N
T
P
Site 77
S504
L
V
G
T
M
M
T
S
N
T
P
E
R
T
S
Site 78
T506
G
T
M
M
T
S
N
T
P
E
R
T
S
Q
G
Site 79
S511
S
N
T
P
E
R
T
S
Q
G
G
A
G
V
S
Site 80
S518
S
Q
G
G
A
G
V
S
P
L
L
V
K
E
E
Site 81
S535
E
D
N
G
L
P
T
S
F
T
L
N
A
A
D
Site 82
T537
N
G
L
P
T
S
F
T
L
N
A
A
D
R
P
Site 83
T548
A
D
R
P
A
N
H
T
K
L
K
D
P
S
E
Site 84
Y556
K
L
K
D
P
S
E
Y
V
A
N
S
A
S
A
Site 85
S560
P
S
E
Y
V
A
N
S
A
S
A
L
F
S
Q
Site 86
S566
N
S
A
S
A
L
F
S
Q
D
I
S
V
K
M
Site 87
S605
E
E
P
K
E
G
E
S
L
S
T
T
L
P
R
Site 88
S607
P
K
E
G
E
S
L
S
T
T
L
P
R
S
S
Site 89
T608
K
E
G
E
S
L
S
T
T
L
P
R
S
S
Y
Site 90
T609
E
G
E
S
L
S
T
T
L
P
R
S
S
Y
V
Site 91
S613
L
S
T
T
L
P
R
S
S
Y
V
F
S
P
E
Site 92
S614
S
T
T
L
P
R
S
S
Y
V
F
S
P
E
S
Site 93
Y615
T
T
L
P
R
S
S
Y
V
F
S
P
E
S
E
Site 94
S618
P
R
S
S
Y
V
F
S
P
E
S
E
V
S
A
Site 95
S621
S
Y
V
F
S
P
E
S
E
V
S
A
P
G
V
Site 96
S624
F
S
P
E
S
E
V
S
A
P
G
V
S
E
D
Site 97
S641
K
P
Q
E
G
K
G
S
V
L
R
R
D
V
S
Site 98
S648
S
V
L
R
R
D
V
S
V
K
A
A
S
E
L
Site 99
S660
S
E
L
L
M
K
L
S
A
E
S
Y
K
E
T
Site 100
Y664
M
K
L
S
A
E
S
Y
K
E
T
Q
M
V
K
Site 101
T667
S
A
E
S
Y
K
E
T
Q
M
V
K
I
K
E
Site 102
S684
M
E
V
D
I
Q
D
S
H
V
S
I
S
P
S
Site 103
S687
D
I
Q
D
S
H
V
S
I
S
P
S
R
N
V
Site 104
S689
Q
D
S
H
V
S
I
S
P
S
R
N
V
G
Y
Site 105
S691
S
H
V
S
I
S
P
S
R
N
V
G
Y
S
T
Site 106
S697
P
S
R
N
V
G
Y
S
T
L
I
G
R
E
K
Site 107
T705
T
L
I
G
R
E
K
T
E
P
L
Q
K
M
P
Site 108
S724
P
P
E
R
N
L
F
S
Q
D
I
S
V
K
M
Site 109
S728
N
L
F
S
Q
D
I
S
V
K
M
A
S
E
L
Site 110
S740
S
E
L
L
F
Q
L
S
E
K
V
S
K
E
H
Site 111
S744
F
Q
L
S
E
K
V
S
K
E
H
N
H
T
K
Site 112
T750
V
S
K
E
H
N
H
T
K
E
N
T
I
R
T
Site 113
T754
H
N
H
T
K
E
N
T
I
R
T
T
T
S
P
Site 114
T758
K
E
N
T
I
R
T
T
T
S
P
F
F
S
E
Site 115
T759
E
N
T
I
R
T
T
T
S
P
F
F
S
E
D
Site 116
S760
N
T
I
R
T
T
T
S
P
F
F
S
E
D
T
Site 117
S764
T
T
T
S
P
F
F
S
E
D
T
F
R
Q
S
Site 118
T767
S
P
F
F
S
E
D
T
F
R
Q
S
P
F
T
Site 119
S771
S
E
D
T
F
R
Q
S
P
F
T
S
N
S
K
Site 120
T774
T
F
R
Q
S
P
F
T
S
N
S
K
E
L
L
Site 121
S775
F
R
Q
S
P
F
T
S
N
S
K
E
L
L
P
Site 122
S777
Q
S
P
F
T
S
N
S
K
E
L
L
P
S
D
Site 123
S783
N
S
K
E
L
L
P
S
D
S
V
L
H
G
R
Site 124
S785
K
E
L
L
P
S
D
S
V
L
H
G
R
I
S
Site 125
S792
S
V
L
H
G
R
I
S
A
P
E
T
E
K
I
Site 126
T796
G
R
I
S
A
P
E
T
E
K
I
V
L
E
A
Site 127
T831
K
V
F
G
R
Q
Q
T
L
S
R
H
L
S
L
Site 128
S833
F
G
R
Q
Q
T
L
S
R
H
L
S
L
H
T
Site 129
S837
Q
T
L
S
R
H
L
S
L
H
T
E
E
R
K
Site 130
Y845
L
H
T
E
E
R
K
Y
K
C
H
L
C
P
Y
Site 131
S881
T
D
T
E
D
I
V
S
A
V
T
S
E
G
S
Site 132
S885
D
I
V
S
A
V
T
S
E
G
S
D
G
K
K
Site 133
S888
S
A
V
T
S
E
G
S
D
G
K
K
H
P
Y
Site 134
Y895
S
D
G
K
K
H
P
Y
Y
Y
S
C
H
V
C
Site 135
Y896
D
G
K
K
H
P
Y
Y
Y
S
C
H
V
C
G
Site 136
Y897
G
K
K
H
P
Y
Y
Y
S
C
H
V
C
G
F
Site 137
T959
H
T
G
E
D
R
K
T
P
S
E
S
N
S
P
Site 138
S961
G
E
D
R
K
T
P
S
E
S
N
S
P
S
S
Site 139
S963
D
R
K
T
P
S
E
S
N
S
P
S
S
S
S
Site 140
S965
K
T
P
S
E
S
N
S
P
S
S
S
S
L
S
Site 141
S967
P
S
E
S
N
S
P
S
S
S
S
L
S
A
L
Site 142
S968
S
E
S
N
S
P
S
S
S
S
L
S
A
L
S
Site 143
S969
E
S
N
S
P
S
S
S
S
L
S
A
L
S
D
Site 144
S970
S
N
S
P
S
S
S
S
L
S
A
L
S
D
S
Site 145
S972
S
P
S
S
S
S
L
S
A
L
S
D
S
A
N
Site 146
S975
S
S
S
L
S
A
L
S
D
S
A
N
S
K
D
Site 147
S977
S
L
S
A
L
S
D
S
A
N
S
K
D
D
S
Site 148
S980
A
L
S
D
S
A
N
S
K
D
D
S
D
G
S
Site 149
S984
S
A
N
S
K
D
D
S
D
G
S
Q
K
N
K
Site 150
S987
S
K
D
D
S
D
G
S
Q
K
N
K
G
G
N
Site 151
S1005
V
I
S
V
M
P
G
S
Q
P
S
L
N
S
E
Site 152
S1008
V
M
P
G
S
Q
P
S
L
N
S
E
E
K
P
Site 153
S1011
G
S
Q
P
S
L
N
S
E
E
K
P
E
K
G
Site 154
T1058
V
C
H
K
F
M
K
T
P
E
Q
L
L
E
H
Site 155
T1070
L
E
H
K
K
C
H
T
V
P
T
G
G
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation