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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LONRF1
Full Name:
LON peptidase N-terminal domain and RING finger protein 1
Alias:
RING finger protein 191
Type:
Mass (Da):
86725
Number AA:
773
UniProt ID:
Q17RB8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
S
P
A
V
A
R
T
Site 2
T9
S
S
P
A
V
A
R
T
S
P
G
G
S
R
E
Site 3
S10
S
P
A
V
A
R
T
S
P
G
G
S
R
E
M
Site 4
S14
A
R
T
S
P
G
G
S
R
E
M
A
P
A
P
Site 5
S45
L
E
R
A
A
A
E
S
E
R
W
E
L
L
L
Site 6
Y142
T
V
P
C
G
H
S
Y
C
R
R
C
L
R
R
Site 7
T166
R
D
R
L
P
P
A
T
A
S
A
T
D
A
E
Site 8
S168
R
L
P
P
A
T
A
S
A
T
D
A
E
G
T
Site 9
Y250
S
D
L
I
V
K
I
Y
R
A
E
S
Y
A
G
Site 10
S254
V
K
I
Y
R
A
E
S
Y
A
G
L
Q
E
F
Site 11
Y282
L
P
D
W
P
E
V
Y
F
R
K
G
K
V
L
Site 12
S339
L
K
E
G
L
K
E
S
S
W
S
S
L
P
C
Site 13
S340
K
E
G
L
K
E
S
S
W
S
S
L
P
C
T
Site 14
S342
G
L
K
E
S
S
W
S
S
L
P
C
T
K
N
Site 15
S343
L
K
E
S
S
W
S
S
L
P
C
T
K
N
R
Site 16
T347
S
W
S
S
L
P
C
T
K
N
R
P
F
D
F
Site 17
S356
N
R
P
F
D
F
H
S
V
M
E
E
S
Q
S
Site 18
S361
F
H
S
V
M
E
E
S
Q
S
L
N
E
P
S
Site 19
S363
S
V
M
E
E
S
Q
S
L
N
E
P
S
P
K
Site 20
S368
S
Q
S
L
N
E
P
S
P
K
Q
S
E
E
I
Site 21
S372
N
E
P
S
P
K
Q
S
E
E
I
P
E
V
T
Site 22
T379
S
E
E
I
P
E
V
T
S
E
P
V
K
G
S
Site 23
S386
T
S
E
P
V
K
G
S
L
N
R
A
Q
S
A
Site 24
S392
G
S
L
N
R
A
Q
S
A
Q
S
I
N
S
T
Site 25
T399
S
A
Q
S
I
N
S
T
E
M
P
A
R
E
D
Site 26
S412
E
D
C
L
K
R
V
S
S
E
P
V
L
S
V
Site 27
S413
D
C
L
K
R
V
S
S
E
P
V
L
S
V
Q
Site 28
T453
K
L
K
K
Q
G
E
T
P
N
E
V
C
M
F
Site 29
Y512
R
C
L
D
H
A
P
Y
C
P
L
C
K
E
S
Site 30
S519
Y
C
P
L
C
K
E
S
L
K
E
Y
L
A
D
Site 31
Y523
C
K
E
S
L
K
E
Y
L
A
D
R
R
Y
C
Site 32
Y529
E
Y
L
A
D
R
R
Y
C
V
T
Q
L
L
E
Site 33
T532
A
D
R
R
Y
C
V
T
Q
L
L
E
E
L
I
Site 34
Y542
L
E
E
L
I
V
K
Y
L
P
D
E
L
S
E
Site 35
S548
K
Y
L
P
D
E
L
S
E
R
K
K
I
Y
D
Site 36
T558
K
K
I
Y
D
E
E
T
A
E
L
S
H
L
T
Site 37
Y591
L
H
V
F
E
P
R
Y
R
L
M
I
R
R
S
Site 38
S598
Y
R
L
M
I
R
R
S
I
Q
T
G
T
K
Q
Site 39
T601
M
I
R
R
S
I
Q
T
G
T
K
Q
F
G
M
Site 40
Y620
T
Q
N
S
F
A
D
Y
G
C
M
L
Q
I
R
Site 41
S637
H
F
L
P
D
G
R
S
V
V
D
T
V
G
G
Site 42
T641
D
G
R
S
V
V
D
T
V
G
G
K
R
F
R
Site 43
Y658
K
R
G
M
K
D
G
Y
C
T
A
D
I
E
Y
Site 44
Y665
Y
C
T
A
D
I
E
Y
L
E
D
V
K
V
E
Site 45
Y688
R
E
L
H
D
L
V
Y
S
Q
A
C
S
W
F
Site 46
S704
N
L
R
D
R
F
R
S
Q
I
L
Q
H
F
G
Site 47
S712
Q
I
L
Q
H
F
G
S
M
P
E
R
E
E
N
Site 48
S746
V
D
P
R
Y
Q
L
S
V
L
S
M
K
S
L
Site 49
S749
R
Y
Q
L
S
V
L
S
M
K
S
L
K
E
R
Site 50
S752
L
S
V
L
S
M
K
S
L
K
E
R
L
T
K
Site 51
T758
K
S
L
K
E
R
L
T
K
I
Q
H
I
L
T
Site 52
T765
T
K
I
Q
H
I
L
T
Y
F
S
R
D
Q
S
Site 53
Y766
K
I
Q
H
I
L
T
Y
F
S
R
D
Q
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation