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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYT16
Full Name:
Synaptotagmin-16
Alias:
Chr14Syt;Synaptotagmin 14-like protein;Synaptotagmin XIV-related protein
Type:
Mass (Da):
72246
Number AA:
645
UniProt ID:
Q17RD7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
Q
P
F
S
S
W
I
S
R
V
Y
E
A
L
Q
Site 2
Y25
S
S
W
I
S
R
V
Y
E
A
L
Q
Q
A
G
Site 3
S43
S
A
S
L
V
N
I
S
K
Q
D
S
K
L
S
Site 4
S47
V
N
I
S
K
Q
D
S
K
L
S
D
K
L
D
Site 5
Y66
N
I
Q
I
Q
E
T
Y
F
E
D
E
E
Q
D
Site 6
S77
E
E
Q
D
N
D
W
S
Q
E
D
A
N
S
L
Site 7
S83
W
S
Q
E
D
A
N
S
L
F
L
E
V
D
H
Site 8
S101
C
N
S
D
L
Q
D
S
A
Q
N
S
S
P
S
Site 9
S105
L
Q
D
S
A
Q
N
S
S
P
S
L
S
Q
H
Site 10
S106
Q
D
S
A
Q
N
S
S
P
S
L
S
Q
H
A
Site 11
S108
S
A
Q
N
S
S
P
S
L
S
Q
H
A
K
D
Site 12
S110
Q
N
S
S
P
S
L
S
Q
H
A
K
D
S
C
Site 13
S116
L
S
Q
H
A
K
D
S
C
S
T
M
S
Q
W
Site 14
S138
R
K
L
P
H
V
L
S
S
I
A
E
E
E
H
Site 15
S139
K
L
P
H
V
L
S
S
I
A
E
E
E
H
H
Site 16
S152
H
H
L
E
K
Q
R
S
G
L
Q
H
G
F
D
Site 17
S160
G
L
Q
H
G
F
D
S
Q
L
P
G
T
L
E
Site 18
T165
F
D
S
Q
L
P
G
T
L
E
T
V
N
G
K
Site 19
T168
Q
L
P
G
T
L
E
T
V
N
G
K
K
Q
V
Site 20
S177
N
G
K
K
Q
V
N
S
F
G
D
D
E
E
L
Site 21
S185
F
G
D
D
E
E
L
S
T
S
S
D
S
D
E
Site 22
T186
G
D
D
E
E
L
S
T
S
S
D
S
D
E
E
Site 23
S187
D
D
E
E
L
S
T
S
S
D
S
D
E
E
V
Site 24
S190
E
L
S
T
S
S
D
S
D
E
E
V
I
K
Q
Site 25
S201
V
I
K
Q
F
E
I
S
V
S
R
S
Q
S
F
Site 26
S203
K
Q
F
E
I
S
V
S
R
S
Q
S
F
R
S
Site 27
S205
F
E
I
S
V
S
R
S
Q
S
F
R
S
V
T
Site 28
S207
I
S
V
S
R
S
Q
S
F
R
S
V
T
S
E
Site 29
S210
S
R
S
Q
S
F
R
S
V
T
S
E
K
G
K
Site 30
T212
S
Q
S
F
R
S
V
T
S
E
K
G
K
Q
T
Site 31
S213
Q
S
F
R
S
V
T
S
E
K
G
K
Q
T
G
Site 32
S230
Q
K
P
K
F
S
R
S
L
L
T
H
G
E
D
Site 33
T239
L
T
H
G
E
D
G
T
E
V
S
A
C
E
D
Site 34
S242
G
E
D
G
T
E
V
S
A
C
E
D
L
D
G
Site 35
S251
C
E
D
L
D
G
A
S
Q
R
R
Y
S
E
N
Site 36
Y255
D
G
A
S
Q
R
R
Y
S
E
N
L
S
Y
G
Site 37
S256
G
A
S
Q
R
R
Y
S
E
N
L
S
Y
G
E
Site 38
S260
R
R
Y
S
E
N
L
S
Y
G
E
D
D
H
I
Site 39
Y261
R
Y
S
E
N
L
S
Y
G
E
D
D
H
I
P
Site 40
S271
D
D
H
I
P
A
H
S
Q
S
P
C
E
R
G
Site 41
S273
H
I
P
A
H
S
Q
S
P
C
E
R
G
D
A
Site 42
S286
D
A
K
H
H
G
T
S
H
Q
E
S
S
V
V
Site 43
S290
H
G
T
S
H
Q
E
S
S
V
V
Q
S
L
R
Site 44
S291
G
T
S
H
Q
E
S
S
V
V
Q
S
L
R
R
Site 45
S295
Q
E
S
S
V
V
Q
S
L
R
R
Q
S
T
E
Site 46
S300
V
Q
S
L
R
R
Q
S
T
E
G
S
L
E
M
Site 47
T301
Q
S
L
R
R
Q
S
T
E
G
S
L
E
M
E
Site 48
S304
R
R
Q
S
T
E
G
S
L
E
M
E
T
A
F
Site 49
T309
E
G
S
L
E
M
E
T
A
F
N
S
R
G
F
Site 50
S319
N
S
R
G
F
E
D
S
Y
A
T
D
S
S
S
Site 51
Y320
S
R
G
F
E
D
S
Y
A
T
D
S
S
S
M
Site 52
T322
G
F
E
D
S
Y
A
T
D
S
S
S
M
W
S
Site 53
S324
E
D
S
Y
A
T
D
S
S
S
M
W
S
P
E
Site 54
S325
D
S
Y
A
T
D
S
S
S
M
W
S
P
E
E
Site 55
S326
S
Y
A
T
D
S
S
S
M
W
S
P
E
E
Q
Site 56
S329
T
D
S
S
S
M
W
S
P
E
E
Q
D
R
T
Site 57
T336
S
P
E
E
Q
D
R
T
N
L
Q
V
P
S
G
Site 58
S342
R
T
N
L
Q
V
P
S
G
V
S
E
P
I
S
Site 59
S345
L
Q
V
P
S
G
V
S
E
P
I
S
K
C
G
Site 60
S349
S
G
V
S
E
P
I
S
K
C
G
D
L
D
V
Site 61
Y360
D
L
D
V
I
F
E
Y
R
A
A
S
Q
K
L
Site 62
T368
R
A
A
S
Q
K
L
T
V
T
I
V
R
A
Q
Site 63
S383
G
L
P
D
K
D
R
S
G
V
N
S
W
Q
V
Site 64
S387
K
D
R
S
G
V
N
S
W
Q
V
H
V
V
L
Site 65
T404
G
K
K
H
R
G
R
T
N
I
Q
R
G
P
N
Site 66
T419
P
V
F
R
E
K
V
T
F
A
K
L
E
P
R
Site 67
Y438
C
A
V
R
F
R
L
Y
A
A
R
K
M
T
R
Site 68
T444
L
Y
A
A
R
K
M
T
R
E
R
M
M
G
E
Site 69
Y455
M
M
G
E
K
L
F
Y
L
S
H
L
H
P
E
Site 70
S457
G
E
K
L
F
Y
L
S
H
L
H
P
E
G
E
Site 71
T468
P
E
G
E
M
K
V
T
L
V
L
E
P
R
S
Site 72
S475
T
L
V
L
E
P
R
S
N
I
S
S
G
G
S
Site 73
S478
L
E
P
R
S
N
I
S
S
G
G
S
P
L
S
Site 74
S479
E
P
R
S
N
I
S
S
G
G
S
P
L
S
P
Site 75
S482
S
N
I
S
S
G
G
S
P
L
S
P
S
A
V
Site 76
S485
S
S
G
G
S
P
L
S
P
S
A
V
S
H
S
Site 77
S487
G
G
S
P
L
S
P
S
A
V
S
H
S
D
S
Site 78
S490
P
L
S
P
S
A
V
S
H
S
D
S
T
S
S
Site 79
S492
S
P
S
A
V
S
H
S
D
S
T
S
S
T
Q
Site 80
S494
S
A
V
S
H
S
D
S
T
S
S
T
Q
S
L
Site 81
S496
V
S
H
S
D
S
T
S
S
T
Q
S
L
S
H
Site 82
S497
S
H
S
D
S
T
S
S
T
Q
S
L
S
H
G
Site 83
T498
H
S
D
S
T
S
S
T
Q
S
L
S
H
G
G
Site 84
S500
D
S
T
S
S
T
Q
S
L
S
H
G
G
A
P
Site 85
S502
T
S
S
T
Q
S
L
S
H
G
G
A
P
E
L
Site 86
S514
P
E
L
L
V
G
L
S
Y
N
A
T
T
G
R
Site 87
T518
V
G
L
S
Y
N
A
T
T
G
R
L
S
V
E
Site 88
T519
G
L
S
Y
N
A
T
T
G
R
L
S
V
E
M
Site 89
S523
N
A
T
T
G
R
L
S
V
E
M
I
K
G
S
Site 90
Y544
V
N
R
A
P
D
T
Y
G
K
L
F
L
L
N
Site 91
S552
G
K
L
F
L
L
N
S
V
G
Q
E
M
S
R
Site 92
S558
N
S
V
G
Q
E
M
S
R
C
K
T
S
I
R
Site 93
T562
Q
E
M
S
R
C
K
T
S
I
R
R
G
Q
P
Site 94
S563
E
M
S
R
C
K
T
S
I
R
R
G
Q
P
N
Site 95
Y573
R
G
Q
P
N
P
V
Y
K
E
T
F
V
F
Q
Site 96
S594
S
D
V
T
L
M
I
S
V
Y
N
R
R
T
M
Site 97
Y596
V
T
L
M
I
S
V
Y
N
R
R
T
M
K
R
Site 98
T600
I
S
V
Y
N
R
R
T
M
K
R
K
E
M
I
Site 99
S617
I
A
L
G
Q
N
S
S
G
E
E
E
Q
D
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation