KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KCTD19
Full Name:
BTB/POZ domain-containing protein KCTD19
Alias:
FLJ40162; KCD19; potassium channel tetramerisation domain containing 19
Type:
Mass (Da):
104919
Number AA:
926
UniProt ID:
Q17RG1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005249
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
N
V
G
G
W
H
F
S
V
P
R
S
K
L
S
Site 2
S29
W
H
F
S
V
P
R
S
K
L
S
Q
F
P
D
Site 3
S32
S
V
P
R
S
K
L
S
Q
F
P
D
S
L
L
Site 4
S37
K
L
S
Q
F
P
D
S
L
L
W
K
E
A
S
Site 5
S44
S
L
L
W
K
E
A
S
A
L
T
S
S
E
S
Site 6
S48
K
E
A
S
A
L
T
S
S
E
S
Q
R
L
F
Site 7
S49
E
A
S
A
L
T
S
S
E
S
Q
R
L
F
I
Site 8
S51
S
A
L
T
S
S
E
S
Q
R
L
F
I
D
R
Site 9
Y68
S
T
F
R
H
V
H
Y
Y
L
Y
T
S
K
L
Site 10
Y69
T
F
R
H
V
H
Y
Y
L
Y
T
S
K
L
S
Site 11
Y71
R
H
V
H
Y
Y
L
Y
T
S
K
L
S
F
S
Site 12
Y129
A
E
R
A
S
L
N
Y
W
R
T
W
K
C
I
Site 13
S140
W
K
C
I
S
K
P
S
E
F
P
I
K
S
P
Site 14
S146
P
S
E
F
P
I
K
S
P
A
F
T
G
L
H
Site 15
T163
A
P
L
G
L
M
D
T
P
L
L
D
T
E
E
Site 16
T168
M
D
T
P
L
L
D
T
E
E
E
V
H
Y
C
Site 17
Y174
D
T
E
E
E
V
H
Y
C
F
L
P
L
D
L
Site 18
Y185
P
L
D
L
V
A
K
Y
P
S
L
V
T
E
D
Site 19
S262
R
M
N
M
G
G
C
S
P
T
T
C
S
P
L
Site 20
T264
N
M
G
G
C
S
P
T
T
C
S
P
L
S
P
Site 21
T265
M
G
G
C
S
P
T
T
C
S
P
L
S
P
G
Site 22
S267
G
C
S
P
T
T
C
S
P
L
S
P
G
K
G
Site 23
S270
P
T
T
C
S
P
L
S
P
G
K
G
A
R
T
Site 24
T277
S
P
G
K
G
A
R
T
A
S
L
E
S
V
K
Site 25
S279
G
K
G
A
R
T
A
S
L
E
S
V
K
P
L
Site 26
S282
A
R
T
A
S
L
E
S
V
K
P
L
Y
T
M
Site 27
Y287
L
E
S
V
K
P
L
Y
T
M
A
L
G
L
L
Site 28
Y297
A
L
G
L
L
V
K
Y
P
D
S
A
L
G
Q
Site 29
S309
L
G
Q
L
R
I
E
S
T
L
D
G
S
R
L
Site 30
T310
G
Q
L
R
I
E
S
T
L
D
G
S
R
L
Y
Site 31
S314
I
E
S
T
L
D
G
S
R
L
Y
I
T
G
N
Site 32
T319
D
G
S
R
L
Y
I
T
G
N
G
V
L
F
Q
Site 33
T340
G
T
C
R
L
P
L
T
E
T
I
S
E
V
Y
Site 34
T359
F
L
D
K
R
D
I
T
Y
E
P
I
K
V
A
Site 35
Y360
L
D
K
R
D
I
T
Y
E
P
I
K
V
A
L
Site 36
T375
K
T
H
L
E
P
R
T
L
A
P
M
D
V
L
Site 37
Y392
W
T
A
E
I
T
V
Y
S
P
Q
Q
I
I
K
Site 38
Y401
P
Q
Q
I
I
K
V
Y
V
G
S
H
W
Y
A
Site 39
T410
G
S
H
W
Y
A
T
T
L
Q
T
L
L
K
Y
Site 40
Y417
T
L
Q
T
L
L
K
Y
P
E
L
L
S
N
P
Site 41
S422
L
K
Y
P
E
L
L
S
N
P
Q
R
V
Y
W
Site 42
Y428
L
S
N
P
Q
R
V
Y
W
I
T
Y
G
Q
T
Site 43
Y476
F
C
Q
E
V
E
E
Y
H
I
P
S
L
S
E
Site 44
S480
V
E
E
Y
H
I
P
S
L
S
E
A
L
A
Q
Site 45
S482
E
Y
H
I
P
S
L
S
E
A
L
A
Q
C
E
Site 46
S493
A
Q
C
E
A
Y
K
S
W
T
Q
E
K
E
S
Site 47
S500
S
W
T
Q
E
K
E
S
E
N
E
E
A
F
S
Site 48
S507
S
E
N
E
E
A
F
S
I
R
R
L
H
V
V
Site 49
S520
V
V
T
E
G
P
G
S
L
V
E
F
S
R
D
Site 50
T528
L
V
E
F
S
R
D
T
K
E
T
T
A
Y
M
Site 51
T531
F
S
R
D
T
K
E
T
T
A
Y
M
P
V
D
Site 52
Y534
D
T
K
E
T
T
A
Y
M
P
V
D
F
E
D
Site 53
T546
F
E
D
C
S
D
R
T
P
W
N
K
A
K
G
Site 54
Y567
Q
M
D
E
A
E
Q
Y
T
R
P
I
Q
V
S
Site 55
S574
Y
T
R
P
I
Q
V
S
L
C
R
N
A
K
R
Site 56
S586
A
K
R
A
G
N
P
S
T
Y
S
H
C
R
G
Site 57
T587
K
R
A
G
N
P
S
T
Y
S
H
C
R
G
L
Site 58
Y588
R
A
G
N
P
S
T
Y
S
H
C
R
G
L
C
Site 59
S603
T
N
P
G
H
W
G
S
H
P
E
S
P
P
K
Site 60
S607
H
W
G
S
H
P
E
S
P
P
K
K
K
C
T
Site 61
S622
T
I
N
L
T
Q
K
S
E
T
K
D
P
P
A
Site 62
T630
E
T
K
D
P
P
A
T
P
M
Q
K
L
I
S
Site 63
S637
T
P
M
Q
K
L
I
S
L
V
R
E
W
D
M
Site 64
T656
Q
W
E
F
Q
P
L
T
A
T
R
S
S
P
L
Site 65
S660
Q
P
L
T
A
T
R
S
S
P
L
E
E
A
T
Site 66
S661
P
L
T
A
T
R
S
S
P
L
E
E
A
T
L
Site 67
T667
S
S
P
L
E
E
A
T
L
Q
L
P
L
G
S
Site 68
S674
T
L
Q
L
P
L
G
S
E
A
A
S
Q
P
S
Site 69
S678
P
L
G
S
E
A
A
S
Q
P
S
T
S
A
A
Site 70
T682
E
A
A
S
Q
P
S
T
S
A
A
W
K
A
H
Site 71
S683
A
A
S
Q
P
S
T
S
A
A
W
K
A
H
S
Site 72
S690
S
A
A
W
K
A
H
S
T
A
S
E
K
D
P
Site 73
T715
K
D
K
G
P
E
P
T
F
K
P
Y
L
P
P
Site 74
Y719
P
E
P
T
F
K
P
Y
L
P
P
K
R
A
G
Site 75
T727
L
P
P
K
R
A
G
T
L
K
D
W
S
K
Q
Site 76
S732
A
G
T
L
K
D
W
S
K
Q
R
T
K
E
R
Site 77
T736
K
D
W
S
K
Q
R
T
K
E
R
E
S
P
A
Site 78
S741
Q
R
T
K
E
R
E
S
P
A
P
E
Q
P
L
Site 79
S752
E
Q
P
L
P
E
A
S
E
V
D
S
L
G
V
Site 80
T785
F
E
D
S
I
I
Y
T
T
E
M
D
N
L
R
Site 81
T794
E
M
D
N
L
R
H
T
T
P
T
A
S
P
Q
Site 82
T795
M
D
N
L
R
H
T
T
P
T
A
S
P
Q
P
Site 83
T797
N
L
R
H
T
T
P
T
A
S
P
Q
P
Q
E
Site 84
S799
R
H
T
T
P
T
A
S
P
Q
P
Q
E
V
T
Site 85
T806
S
P
Q
P
Q
E
V
T
F
L
S
F
S
L
S
Site 86
S809
P
Q
E
V
T
F
L
S
F
S
L
S
W
E
E
Site 87
S834
L
A
D
I
I
M
D
S
I
R
Q
K
D
P
K
Site 88
T856
S
L
A
N
R
L
W
T
L
H
I
S
P
K
Q
Site 89
S860
R
L
W
T
L
H
I
S
P
K
Q
F
V
V
D
Site 90
T880
G
F
K
D
D
R
H
T
Q
E
R
L
Y
S
W
Site 91
Y885
R
H
T
Q
E
R
L
Y
S
W
V
E
L
T
L
Site 92
S886
H
T
Q
E
R
L
Y
S
W
V
E
L
T
L
P
Site 93
Y898
T
L
P
F
A
R
K
Y
G
R
C
M
D
L
L
Site 94
S913
I
Q
R
G
L
S
R
S
V
S
Y
S
I
L
G
Site 95
S915
R
G
L
S
R
S
V
S
Y
S
I
L
G
K
Y
Site 96
S917
L
S
R
S
V
S
Y
S
I
L
G
K
Y
L
Q
Site 97
Y922
S
Y
S
I
L
G
K
Y
L
Q
E
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation