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Updated November 2019
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Protein Info
Short Name:
CCDC142
Full Name:
Coiled-coil domain-containing protein 142
Alias:
Type:
Mass (Da):
81643
Number AA:
750
UniProt ID:
Q17RM4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
Q
A
S
R
S
G
S
L
P
P
Site 2
T36
E
Q
W
E
R
S
R
T
G
G
L
R
W
E
V
Site 3
T54
P
S
G
T
S
G
G
T
P
W
W
P
T
P
A
Site 4
T59
G
G
T
P
W
W
P
T
P
A
D
V
S
E
D
Site 5
Y67
P
A
D
V
S
E
D
Y
E
A
D
A
A
A
W
Site 6
Y113
L
Q
A
R
D
C
A
Y
H
L
Q
S
A
V
R
Site 7
T124
S
A
V
R
L
M
K
T
L
S
P
G
S
P
S
Site 8
S126
V
R
L
M
K
T
L
S
P
G
S
P
S
G
G
Site 9
S129
M
K
T
L
S
P
G
S
P
S
G
G
P
S
P
Site 10
S131
T
L
S
P
G
S
P
S
G
G
P
S
P
L
P
Site 11
S135
G
S
P
S
G
G
P
S
P
L
P
Q
W
C
R
Site 12
S149
R
D
L
Q
L
H
P
S
Q
G
A
V
L
R
I
Site 13
S195
A
L
G
R
E
P
A
S
P
G
L
S
S
Q
L
Site 14
S199
E
P
A
S
P
G
L
S
S
Q
L
A
E
L
L
Site 15
T214
F
A
L
P
A
Y
H
T
L
Q
R
K
A
L
S
Site 16
S221
T
L
Q
R
K
A
L
S
H
V
P
G
A
A
R
Site 17
T240
S
R
V
L
R
L
L
T
G
E
R
G
C
Q
V
Site 18
T330
P
W
R
D
P
R
A
T
A
Q
Q
L
S
Q
A
Site 19
S335
R
A
T
A
Q
Q
L
S
Q
A
L
G
Q
A
S
Site 20
S342
S
Q
A
L
G
Q
A
S
L
P
Q
E
C
E
K
Site 21
S353
E
C
E
K
E
L
A
S
L
C
H
R
L
L
H
Site 22
S383
G
S
A
L
G
G
Q
S
S
L
P
T
S
S
G
Site 23
S384
S
A
L
G
G
Q
S
S
L
P
T
S
S
G
T
Site 24
T387
G
G
Q
S
S
L
P
T
S
S
G
T
A
E
L
Site 25
S388
G
Q
S
S
L
P
T
S
S
G
T
A
E
L
L
Site 26
S389
Q
S
S
L
P
T
S
S
G
T
A
E
L
L
Q
Site 27
S474
H
E
A
E
A
L
Y
S
L
A
S
E
E
S
L
Site 28
S477
E
A
L
Y
S
L
A
S
E
E
S
L
A
L
E
Site 29
S480
Y
S
L
A
S
E
E
S
L
A
L
E
V
E
Q
Site 30
S507
I
Q
L
L
P
E
E
S
L
S
V
F
S
Q
E
Site 31
S509
L
L
P
E
E
S
L
S
V
F
S
Q
E
C
H
Site 32
Y526
A
M
Q
G
F
K
L
Y
M
P
R
G
R
Y
W
Site 33
Y532
L
Y
M
P
R
G
R
Y
W
R
L
R
L
C
P
Site 34
S543
R
L
C
P
E
P
P
S
A
P
S
E
Y
A
G
Site 35
S546
P
E
P
P
S
A
P
S
E
Y
A
G
L
V
V
Site 36
S623
L
L
E
E
E
Q
W
S
L
S
P
D
L
R
Q
Site 37
S625
E
E
E
Q
W
S
L
S
P
D
L
R
Q
T
L
Site 38
S656
L
Q
Q
P
L
P
K
S
Q
V
H
R
R
P
P
Site 39
T674
A
C
Q
E
V
Q
T
T
K
L
P
S
S
C
L
Site 40
S679
Q
T
T
K
L
P
S
S
C
L
N
S
L
E
S
Site 41
S683
L
P
S
S
C
L
N
S
L
E
S
L
E
P
P
Site 42
S686
S
C
L
N
S
L
E
S
L
E
P
P
L
Q
P
Site 43
S696
P
P
L
Q
P
G
T
S
P
A
Q
T
G
Q
L
Site 44
T700
P
G
T
S
P
A
Q
T
G
Q
L
Q
S
T
L
Site 45
T706
Q
T
G
Q
L
Q
S
T
L
G
G
R
G
P
S
Site 46
S713
T
L
G
G
R
G
P
S
P
E
G
Y
L
V
G
Site 47
Y717
R
G
P
S
P
E
G
Y
L
V
G
N
Q
Q
A
Site 48
S742
R
W
H
L
P
F
F
S
C
L
G
T
S
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation