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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPEB4
Full Name:
Cytoplasmic polyadenylation element-binding protein 4
Alias:
CPEB-4; CPE-binding 4; CPE-BP4; Cytoplasmic polyadenylation element binding protein 4; KIAA1673
Type:
Unknown function
Mass (Da):
80152
Number AA:
729
UniProt ID:
Q17RY0
International Prot ID:
IPI00375652
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
F
G
V
L
V
Q
S
N
T
G
N
K
S
A
Site 2
T14
G
V
L
V
Q
S
N
T
G
N
K
S
A
F
P
Site 3
S18
Q
S
N
T
G
N
K
S
A
F
P
V
R
F
H
Site 4
T38
P
H
H
H
Q
N
A
T
P
S
P
A
A
F
I
Site 5
S40
H
H
Q
N
A
T
P
S
P
A
A
F
I
N
N
Site 6
S77
I
Q
D
E
I
L
G
S
E
K
A
K
S
Q
Q
Site 7
S82
L
G
S
E
K
A
K
S
Q
Q
Q
E
Q
Q
D
Site 8
S97
P
L
E
K
Q
Q
L
S
P
S
P
G
Q
E
A
Site 9
S99
E
K
Q
Q
L
S
P
S
P
G
Q
E
A
G
I
Site 10
T110
E
A
G
I
L
P
E
T
E
K
A
K
S
E
E
Site 11
S115
P
E
T
E
K
A
K
S
E
E
N
Q
G
D
N
Site 12
S123
E
E
N
Q
G
D
N
S
S
E
N
G
N
G
K
Site 13
S124
E
N
Q
G
D
N
S
S
E
N
G
N
G
K
E
Site 14
S137
K
E
K
I
R
I
E
S
P
V
L
T
G
F
D
Site 15
T141
R
I
E
S
P
V
L
T
G
F
D
Y
Q
E
A
Site 16
Y145
P
V
L
T
G
F
D
Y
Q
E
A
T
G
L
G
Site 17
S154
E
A
T
G
L
G
T
S
T
Q
P
L
T
S
S
Site 18
T155
A
T
G
L
G
T
S
T
Q
P
L
T
S
S
A
Site 19
T159
G
T
S
T
Q
P
L
T
S
S
A
S
S
L
T
Site 20
S160
T
S
T
Q
P
L
T
S
S
A
S
S
L
T
G
Site 21
S161
S
T
Q
P
L
T
S
S
A
S
S
L
T
G
F
Site 22
S163
Q
P
L
T
S
S
A
S
S
L
T
G
F
S
N
Site 23
S164
P
L
T
S
S
A
S
S
L
T
G
F
S
N
W
Site 24
S179
S
A
A
I
A
P
S
S
S
T
I
I
N
E
D
Site 25
S215
Q
N
F
P
H
H
V
S
P
G
F
G
G
S
F
Site 26
S221
V
S
P
G
F
G
G
S
F
S
P
Q
I
G
P
Site 27
S223
P
G
F
G
G
S
F
S
P
Q
I
G
P
L
S
Site 28
S230
S
P
Q
I
G
P
L
S
Q
H
H
P
H
H
P
Site 29
S252
Q
H
Q
Q
Q
R
R
S
P
A
S
P
H
P
P
Site 30
S255
Q
Q
R
R
S
P
A
S
P
H
P
P
P
F
T
Site 31
T262
S
P
H
P
P
P
F
T
H
R
N
A
A
F
N
Site 32
S283
N
N
L
N
K
P
P
S
P
W
S
S
Y
Q
S
Site 33
S286
N
K
P
P
S
P
W
S
S
Y
Q
S
P
S
P
Site 34
S287
K
P
P
S
P
W
S
S
Y
Q
S
P
S
P
T
Site 35
Y288
P
P
S
P
W
S
S
Y
Q
S
P
S
P
T
P
Site 36
S290
S
P
W
S
S
Y
Q
S
P
S
P
T
P
S
S
Site 37
S292
W
S
S
Y
Q
S
P
S
P
T
P
S
S
S
W
Site 38
T294
S
Y
Q
S
P
S
P
T
P
S
S
S
W
S
P
Site 39
S296
Q
S
P
S
P
T
P
S
S
S
W
S
P
G
G
Site 40
S297
S
P
S
P
T
P
S
S
S
W
S
P
G
G
G
Site 41
S298
P
S
P
T
P
S
S
S
W
S
P
G
G
G
G
Site 42
S300
P
T
P
S
S
S
W
S
P
G
G
G
G
Y
G
Site 43
Y306
W
S
P
G
G
G
G
Y
G
G
W
G
G
S
Q
Site 44
S312
G
Y
G
G
W
G
G
S
Q
G
R
D
H
R
R
Site 45
T326
R
G
L
N
G
G
I
T
P
L
N
S
I
S
P
Site 46
S330
G
G
I
T
P
L
N
S
I
S
P
L
K
K
N
Site 47
S332
I
T
P
L
N
S
I
S
P
L
K
K
N
F
A
Site 48
Y348
N
H
I
Q
L
Q
K
Y
A
R
P
S
S
A
F
Site 49
S352
L
Q
K
Y
A
R
P
S
S
A
F
A
P
K
S
Site 50
S353
Q
K
Y
A
R
P
S
S
A
F
A
P
K
S
W
Site 51
S359
S
S
A
F
A
P
K
S
W
M
E
D
S
L
N
Site 52
S364
P
K
S
W
M
E
D
S
L
N
R
A
D
N
I
Site 53
T380
P
F
P
D
R
P
R
T
F
D
M
H
S
L
E
Site 54
S385
P
R
T
F
D
M
H
S
L
E
S
S
L
I
D
Site 55
S389
D
M
H
S
L
E
S
S
L
I
D
I
M
R
A
Site 56
T400
I
M
R
A
E
N
D
T
I
K
G
R
L
N
Y
Site 57
Y407
T
I
K
G
R
L
N
Y
S
Y
P
G
S
D
S
Site 58
S408
I
K
G
R
L
N
Y
S
Y
P
G
S
D
S
S
Site 59
Y409
K
G
R
L
N
Y
S
Y
P
G
S
D
S
S
L
Site 60
S412
L
N
Y
S
Y
P
G
S
D
S
S
L
L
I
N
Site 61
S415
S
Y
P
G
S
D
S
S
L
L
I
N
A
R
T
Site 62
T422
S
L
L
I
N
A
R
T
Y
G
R
R
R
G
Q
Site 63
Y423
L
L
I
N
A
R
T
Y
G
R
R
R
G
Q
S
Site 64
S430
Y
G
R
R
R
G
Q
S
S
L
F
P
M
E
D
Site 65
S431
G
R
R
R
G
Q
S
S
L
F
P
M
E
D
G
Site 66
S451
R
G
D
Q
P
L
H
S
G
L
G
S
P
H
C
Site 67
S455
P
L
H
S
G
L
G
S
P
H
C
F
S
H
Q
Site 68
S460
L
G
S
P
H
C
F
S
H
Q
N
G
E
R
V
Site 69
Y470
N
G
E
R
V
E
R
Y
S
R
K
V
F
V
G
Site 70
S471
G
E
R
V
E
R
Y
S
R
K
V
F
V
G
G
Site 71
T489
D
I
D
E
D
E
I
T
A
S
F
R
R
F
G
Site 72
S491
D
E
D
E
I
T
A
S
F
R
R
F
G
P
L
Site 73
S508
D
W
P
H
K
A
E
S
K
S
Y
F
P
P
K
Site 74
S510
P
H
K
A
E
S
K
S
Y
F
P
P
K
G
Y
Site 75
Y511
H
K
A
E
S
K
S
Y
F
P
P
K
G
Y
A
Site 76
Y543
I
E
E
D
G
K
L
Y
L
C
V
S
S
P
T
Site 77
S547
G
K
L
Y
L
C
V
S
S
P
T
I
K
D
K
Site 78
S548
K
L
Y
L
C
V
S
S
P
T
I
K
D
K
P
Site 79
S564
Q
I
R
P
W
N
L
S
D
S
D
F
V
M
D
Site 80
S566
R
P
W
N
L
S
D
S
D
F
V
M
D
G
S
Site 81
S573
S
D
F
V
M
D
G
S
Q
P
L
D
P
R
K
Site 82
T581
Q
P
L
D
P
R
K
T
I
F
V
G
G
V
P
Site 83
Y604
A
M
I
M
D
R
L
Y
G
G
V
C
Y
A
G
Site 84
Y609
R
L
Y
G
G
V
C
Y
A
G
I
D
T
D
P
Site 85
T614
V
C
Y
A
G
I
D
T
D
P
E
L
K
Y
P
Site 86
Y620
D
T
D
P
E
L
K
Y
P
K
G
A
G
R
V
Site 87
S630
G
A
G
R
V
A
F
S
N
Q
Q
S
Y
I
A
Site 88
Y635
A
F
S
N
Q
Q
S
Y
I
A
A
I
S
A
R
Site 89
Y660
K
R
V
E
V
K
P
Y
V
L
D
D
Q
L
C
Site 90
S725
G
D
R
P
R
H
I
S
F
R
W
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation