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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LONRF2
Full Name:
LON peptidase N-terminal domain and RING finger protein 2
Alias:
Neuroblastoma apoptosis-related protease;RING finger protein 192
Type:
Mass (Da):
83638
Number AA:
754
UniProt ID:
Q1L5Z9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
E
A
F
R
A
G
D
Y
E
M
A
A
E
L
F
Site 2
S114
G
L
R
D
R
P
L
S
A
E
N
P
G
G
E
Site 3
S206
R
L
A
G
Q
A
R
S
L
Q
R
Q
Q
Q
P
Site 4
S232
E
L
A
P
D
D
N
S
L
L
L
L
R
A
E
Site 5
Y241
L
L
L
R
A
E
L
Y
L
T
M
K
N
Y
E
Site 6
T243
L
R
A
E
L
Y
L
T
M
K
N
Y
E
Q
A
Site 7
S326
N
V
H
E
N
L
T
S
S
I
Q
S
R
L
K
Site 8
S330
N
L
T
S
S
I
Q
S
R
L
K
A
Q
G
H
Site 9
S353
L
E
E
G
D
A
G
S
S
E
N
S
S
E
K
Site 10
S354
E
E
G
D
A
G
S
S
E
N
S
S
E
K
S
Site 11
S357
D
A
G
S
S
E
N
S
S
E
K
S
D
M
L
Site 12
S358
A
G
S
S
E
N
S
S
E
K
S
D
M
L
G
Site 13
S361
S
E
N
S
S
E
K
S
D
M
L
G
N
T
N
Site 14
T367
K
S
D
M
L
G
N
T
N
S
S
V
L
Y
F
Site 15
S396
S
I
L
P
T
A
P
S
A
G
L
K
R
Q
F
Site 16
S425
K
I
P
K
K
D
L
S
P
Q
R
S
P
N
S
Site 17
S429
K
D
L
S
P
Q
R
S
P
N
S
E
T
E
E
Site 18
S432
S
P
Q
R
S
P
N
S
E
T
E
E
S
Q
G
Site 19
S437
P
N
S
E
T
E
E
S
Q
G
L
S
L
D
V
Site 20
S441
T
E
E
S
Q
G
L
S
L
D
V
T
D
F
E
Site 21
S491
P
L
C
K
D
K
L
S
E
L
L
A
S
R
N
Site 22
Y512
A
E
E
L
I
F
R
Y
L
P
D
E
L
S
D
Site 23
S518
R
Y
L
P
D
E
L
S
D
R
K
R
I
Y
D
Site 24
Y524
L
S
D
R
K
R
I
Y
D
E
E
M
S
E
L
Site 25
Y561
L
H
V
F
E
P
R
Y
R
L
M
I
R
R
C
Site 26
T571
M
I
R
R
C
M
E
T
G
T
K
R
F
G
M
Site 27
S581
K
R
F
G
M
C
L
S
A
E
H
A
G
L
S
Site 28
S588
S
A
E
H
A
G
L
S
E
Y
G
C
M
L
E
Site 29
Y590
E
H
A
G
L
S
E
Y
G
C
M
L
E
I
K
Site 30
T601
L
E
I
K
D
V
R
T
F
P
D
G
S
S
V
Site 31
S606
V
R
T
F
P
D
G
S
S
V
V
D
A
I
G
Site 32
S621
I
S
R
F
R
V
L
S
H
R
H
R
D
G
Y
Site 33
Y628
S
H
R
H
R
D
G
Y
N
T
A
D
I
E
Y
Site 34
T630
R
H
R
D
G
Y
N
T
A
D
I
E
Y
L
E
Site 35
Y635
Y
N
T
A
D
I
E
Y
L
E
D
E
K
V
E
Site 36
Y646
E
K
V
E
G
P
E
Y
E
E
L
A
A
L
H
Site 37
S655
E
L
A
A
L
H
D
S
V
H
Q
Q
S
V
S
Site 38
S660
H
D
S
V
H
Q
Q
S
V
S
W
F
A
S
L
Site 39
S662
S
V
H
Q
Q
S
V
S
W
F
A
S
L
Q
D
Site 40
S666
Q
S
V
S
W
F
A
S
L
Q
D
R
M
K
E
Site 41
S691
D
R
E
P
E
P
Q
S
N
P
S
G
P
A
W
Site 42
S694
P
E
P
Q
S
N
P
S
G
P
A
W
S
W
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation