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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C10orf140
Full Name:
Protein DLN-1
Alias:
Type:
Mass (Da):
90476
Number AA:
827
UniProt ID:
Q1XH10
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
D
L
K
S
G
F
E
E
V
D
G
Site 2
T34
F
A
L
S
Q
V
F
T
D
L
L
K
N
I
P
Site 3
T43
L
L
K
N
I
P
R
T
T
V
H
K
R
M
D
Site 4
T44
L
K
N
I
P
R
T
T
V
H
K
R
M
D
H
Site 5
S72
R
K
L
K
A
I
N
S
I
A
F
H
A
A
K
Site 6
Y92
R
E
D
V
E
A
L
Y
T
S
C
K
T
E
R
Site 7
T93
E
D
V
E
A
L
Y
T
S
C
K
T
E
R
V
Site 8
T97
A
L
Y
T
S
C
K
T
E
R
V
L
K
T
K
Site 9
T103
K
T
E
R
V
L
K
T
K
R
R
R
V
G
R
Site 10
T114
R
V
G
R
A
L
A
T
K
A
P
P
P
E
R
Site 11
S126
P
E
R
A
A
A
A
S
P
R
P
G
F
W
K
Site 12
S143
H
Q
L
W
R
G
L
S
G
A
A
R
P
L
P
Site 13
S152
A
A
R
P
L
P
I
S
A
Q
S
Q
R
P
G
Site 14
S155
P
L
P
I
S
A
Q
S
Q
R
P
G
A
A
A
Site 15
Y176
L
P
Q
I
F
S
K
Y
P
G
S
H
Y
P
E
Site 16
S179
I
F
S
K
Y
P
G
S
H
Y
P
E
I
V
R
Site 17
Y181
S
K
Y
P
G
S
H
Y
P
E
I
V
R
S
P
Site 18
S187
H
Y
P
E
I
V
R
S
P
C
K
P
P
L
N
Site 19
Y204
T
A
P
L
Q
G
N
Y
V
A
F
P
S
D
P
Site 20
S209
G
N
Y
V
A
F
P
S
D
P
A
Y
F
R
S
Site 21
S216
S
D
P
A
Y
F
R
S
L
L
C
S
K
H
P
Site 22
S293
R
P
Q
P
H
L
G
S
F
P
E
S
C
S
S
Site 23
S297
H
L
G
S
F
P
E
S
C
S
S
D
S
E
S
Site 24
S299
G
S
F
P
E
S
C
S
S
D
S
E
S
S
S
Site 25
S300
S
F
P
E
S
C
S
S
D
S
E
S
S
S
Y
Site 26
S302
P
E
S
C
S
S
D
S
E
S
S
S
Y
S
D
Site 27
S304
S
C
S
S
D
S
E
S
S
S
Y
S
D
H
A
Site 28
S306
S
S
D
S
E
S
S
S
Y
S
D
H
A
A
N
Site 29
Y307
S
D
S
E
S
S
S
Y
S
D
H
A
A
N
D
Site 30
S308
D
S
E
S
S
S
Y
S
D
H
A
A
N
D
S
Site 31
S315
S
D
H
A
A
N
D
S
D
F
G
S
S
L
S
Site 32
S319
A
N
D
S
D
F
G
S
S
L
S
S
S
S
N
Site 33
S320
N
D
S
D
F
G
S
S
L
S
S
S
S
N
S
Site 34
S322
S
D
F
G
S
S
L
S
S
S
S
N
S
V
S
Site 35
S323
D
F
G
S
S
L
S
S
S
S
N
S
V
S
S
Site 36
S324
F
G
S
S
L
S
S
S
S
N
S
V
S
S
E
Site 37
S325
G
S
S
L
S
S
S
S
N
S
V
S
S
E
E
Site 38
S327
S
L
S
S
S
S
N
S
V
S
S
E
E
E
E
Site 39
S329
S
S
S
S
N
S
V
S
S
E
E
E
E
E
E
Site 40
S330
S
S
S
N
S
V
S
S
E
E
E
E
E
E
G
Site 41
S350
E
E
E
E
E
G
G
S
G
A
S
D
S
S
E
Site 42
S353
E
E
G
G
S
G
A
S
D
S
S
E
V
S
S
Site 43
S355
G
G
S
G
A
S
D
S
S
E
V
S
S
E
E
Site 44
S356
G
S
G
A
S
D
S
S
E
V
S
S
E
E
E
Site 45
S359
A
S
D
S
S
E
V
S
S
E
E
E
D
S
S
Site 46
S360
S
D
S
S
E
V
S
S
E
E
E
D
S
S
T
Site 47
S365
V
S
S
E
E
E
D
S
S
T
E
S
D
S
S
Site 48
S366
S
S
E
E
E
D
S
S
T
E
S
D
S
S
S
Site 49
T367
S
E
E
E
D
S
S
T
E
S
D
S
S
S
G
Site 50
S369
E
E
D
S
S
T
E
S
D
S
S
S
G
S
S
Site 51
S371
D
S
S
T
E
S
D
S
S
S
G
S
S
Q
V
Site 52
S372
S
S
T
E
S
D
S
S
S
G
S
S
Q
V
S
Site 53
S373
S
T
E
S
D
S
S
S
G
S
S
Q
V
S
V
Site 54
S375
E
S
D
S
S
S
G
S
S
Q
V
S
V
Q
S
Site 55
S376
S
D
S
S
S
G
S
S
Q
V
S
V
Q
S
I
Site 56
S379
S
S
G
S
S
Q
V
S
V
Q
S
I
R
F
R
Site 57
S382
S
S
Q
V
S
V
Q
S
I
R
F
R
R
T
S
Site 58
T388
Q
S
I
R
F
R
R
T
S
F
C
K
P
P
S
Site 59
S389
S
I
R
F
R
R
T
S
F
C
K
P
P
S
V
Site 60
S395
T
S
F
C
K
P
P
S
V
Q
A
Q
A
N
F
Site 61
S429
G
R
L
P
D
L
K
S
S
V
K
A
E
S
P
Site 62
S430
R
L
P
D
L
K
S
S
V
K
A
E
S
P
A
Site 63
S435
K
S
S
V
K
A
E
S
P
A
E
W
N
L
Q
Site 64
S443
P
A
E
W
N
L
Q
S
W
A
P
K
A
S
P
Site 65
S449
Q
S
W
A
P
K
A
S
P
V
Y
C
P
A
S
Site 66
S470
E
I
R
N
D
R
V
S
E
I
T
F
P
H
S
Site 67
T473
N
D
R
V
S
E
I
T
F
P
H
S
E
I
S
Site 68
S477
S
E
I
T
F
P
H
S
E
I
S
N
A
V
K
Site 69
S499
C
L
A
E
G
A
S
S
P
S
P
K
T
N
N
Site 70
S501
A
E
G
A
S
S
P
S
P
K
T
N
N
A
F
Site 71
T504
A
S
S
P
S
P
K
T
N
N
A
F
P
Q
Q
Site 72
T523
E
A
R
K
C
L
Q
T
T
P
T
T
H
C
A
Site 73
T524
A
R
K
C
L
Q
T
T
P
T
T
H
C
A
D
Site 74
S545
R
F
L
N
N
D
S
S
G
A
E
A
N
S
E
Site 75
S551
S
S
G
A
E
A
N
S
E
K
Y
S
K
I
L
Site 76
S555
E
A
N
S
E
K
Y
S
K
I
L
H
C
P
E
Site 77
T565
L
H
C
P
E
F
A
T
D
L
P
S
S
Q
T
Site 78
S569
E
F
A
T
D
L
P
S
S
Q
T
D
P
E
V
Site 79
S570
F
A
T
D
L
P
S
S
Q
T
D
P
E
V
N
Site 80
T591
T
K
A
E
N
P
C
T
D
T
G
D
K
T
L
Site 81
T593
A
E
N
P
C
T
D
T
G
D
K
T
L
P
F
Site 82
T597
C
T
D
T
G
D
K
T
L
P
F
L
H
N
I
Site 83
S611
I
K
I
K
V
E
D
S
S
A
N
E
E
Y
E
Site 84
S612
K
I
K
V
E
D
S
S
A
N
E
E
Y
E
P
Site 85
T633
L
K
C
E
C
N
D
T
K
G
E
F
Y
S
V
Site 86
S639
D
T
K
G
E
F
Y
S
V
T
E
S
K
E
E
Site 87
T641
K
G
E
F
Y
S
V
T
E
S
K
E
E
D
A
Site 88
S643
E
F
Y
S
V
T
E
S
K
E
E
D
A
L
L
Site 89
T664
F
A
C
P
E
K
E
T
P
S
L
N
P
L
A
Site 90
S666
C
P
E
K
E
T
P
S
L
N
P
L
A
Q
S
Site 91
S677
L
A
Q
S
Q
G
L
S
C
T
L
G
S
P
K
Site 92
S682
G
L
S
C
T
L
G
S
P
K
P
E
D
G
E
Site 93
Y690
P
K
P
E
D
G
E
Y
K
F
G
A
R
V
R
Site 94
Y700
G
A
R
V
R
K
N
Y
R
T
L
V
L
G
K
Site 95
T702
R
V
R
K
N
Y
R
T
L
V
L
G
K
R
P
Site 96
T713
G
K
R
P
V
L
Q
T
P
P
V
K
P
N
L
Site 97
S722
P
V
K
P
N
L
K
S
A
R
S
P
R
P
T
Site 98
S725
P
N
L
K
S
A
R
S
P
R
P
T
G
K
T
Site 99
T729
S
A
R
S
P
R
P
T
G
K
T
E
T
N
E
Site 100
T732
S
P
R
P
T
G
K
T
E
T
N
E
G
T
L
Site 101
T743
E
G
T
L
D
D
F
T
V
I
N
R
R
K
K
Site 102
S753
N
R
R
K
K
V
A
S
N
V
A
S
A
V
K
Site 103
S757
K
V
A
S
N
V
A
S
A
V
K
R
P
F
H
Site 104
Y787
D
G
D
L
W
P
A
Y
S
L
N
T
T
K
D
Site 105
S788
G
D
L
W
P
A
Y
S
L
N
T
T
K
D
S
Site 106
T792
P
A
Y
S
L
N
T
T
K
D
S
Q
T
P
H
Site 107
S795
S
L
N
T
T
K
D
S
Q
T
P
H
K
A
H
Site 108
T797
N
T
T
K
D
S
Q
T
P
H
K
A
H
P
I
Site 109
S819
S
A
I
P
L
P
P
S
H
K
F
R
K
F
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation