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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INF2
Full Name:
Inverted formin-2
Alias:
C14orf151; C14orf173; Chromosome 14 open reading frame 173 isoform 1; HBEBP2-binding protein C; Inverted formin 2; Inverted formin, FH2 and WH2 domain containing; MGC13251
Type:
Unknown function
Mass (Da):
135624
Number AA:
1249
UniProt ID:
Q27J81
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0017048
GO:0003779
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0016043
GO:0030029
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
K
L
G
P
Q
D
S
D
P
T
E
A
N
L
Site 2
T26
G
P
Q
D
S
D
P
T
E
A
N
L
E
S
A
Site 3
S93
G
R
G
V
A
R
I
S
D
A
L
L
Q
L
T
Site 4
T100
S
D
A
L
L
Q
L
T
C
V
S
C
V
R
A
Site 5
Y117
N
S
R
Q
G
I
E
Y
I
L
S
N
Q
G
Y
Site 6
Y124
Y
I
L
S
N
Q
G
Y
V
R
Q
L
S
Q
A
Site 7
S129
Q
G
Y
V
R
Q
L
S
Q
A
L
D
T
S
N
Site 8
T134
Q
L
S
Q
A
L
D
T
S
N
V
M
V
K
K
Site 9
S135
L
S
Q
A
L
D
T
S
N
V
M
V
K
K
Q
Site 10
T161
S
P
E
G
H
V
L
T
L
D
A
L
D
H
Y
Site 11
Y168
T
L
D
A
L
D
H
Y
K
T
V
C
S
Q
Q
Site 12
T170
D
A
L
D
H
Y
K
T
V
C
S
Q
Q
Y
R
Site 13
S186
S
I
V
M
N
E
L
S
G
S
D
N
V
P
Y
Site 14
T215
P
E
D
L
R
A
R
T
Q
L
R
N
E
F
I
Site 15
S263
E
E
E
L
L
R
V
S
G
G
V
D
M
S
S
Site 16
S269
V
S
G
G
V
D
M
S
S
H
Q
E
V
F
A
Site 17
S270
S
G
G
V
D
M
S
S
H
Q
E
V
F
A
S
Site 18
S277
S
H
Q
E
V
F
A
S
L
F
H
K
V
S
C
Site 19
S308
L
E
P
T
L
R
S
S
Q
L
L
W
E
A
L
Site 20
S343
E
V
V
E
R
L
L
S
V
K
G
R
P
R
P
Site 21
S351
V
K
G
R
P
R
P
S
P
L
V
K
A
H
K
Site 22
S359
P
L
V
K
A
H
K
S
V
Q
A
N
L
D
Q
Site 23
S367
V
Q
A
N
L
D
Q
S
Q
R
G
S
S
P
Q
Site 24
S371
L
D
Q
S
Q
R
G
S
S
P
Q
N
T
T
T
Site 25
S372
D
Q
S
Q
R
G
S
S
P
Q
N
T
T
T
P
Site 26
T376
R
G
S
S
P
Q
N
T
T
T
P
K
P
S
V
Site 27
T378
S
S
P
Q
N
T
T
T
P
K
P
S
V
E
G
Site 28
S409
S
E
S
I
L
K
V
S
Q
P
R
A
L
E
Q
Site 29
S419
Q
A
E
A
D
S
T
S
E
G
L
E
D
A
V
Site 30
T420
A
L
E
Q
Q
A
S
T
P
P
P
P
P
P
P
Site 31
S433
P
P
P
L
L
P
G
S
S
A
E
P
P
P
P
Site 32
S434
P
P
L
L
P
G
S
S
A
E
P
P
P
P
P
Site 33
S448
P
P
P
P
P
L
P
S
V
G
A
K
A
L
P
Site 34
S483
L
P
P
P
L
P
G
S
C
E
F
L
P
P
P
Site 35
S527
P
L
L
P
C
T
C
S
P
P
V
A
G
G
M
Site 36
S548
Q
V
D
H
G
L
G
S
A
W
V
P
S
H
R
Site 37
S553
L
G
S
A
W
V
P
S
H
R
R
V
N
P
P
Site 38
T561
H
R
R
V
N
P
P
T
L
R
M
K
K
L
N
Site 39
S582
N
V
A
R
E
H
N
S
M
W
A
S
L
S
S
Site 40
S586
E
H
N
S
M
W
A
S
L
S
S
P
D
A
E
Site 41
S588
N
S
M
W
A
S
L
S
S
P
D
A
E
A
V
Site 42
S589
S
M
W
A
S
L
S
S
P
D
A
E
A
V
E
Site 43
S600
E
A
V
E
P
D
F
S
S
I
E
R
L
F
S
Site 44
S607
S
S
I
E
R
L
F
S
F
P
A
A
K
P
K
Site 45
T617
A
A
K
P
K
E
P
T
M
V
A
P
R
A
R
Site 46
T631
R
K
E
P
K
E
I
T
F
L
D
A
K
K
S
Site 47
T692
I
E
N
L
R
A
F
T
E
E
R
A
K
L
A
Site 48
S700
E
E
R
A
K
L
A
S
A
D
H
F
Y
L
L
Site 49
Y770
R
I
G
N
F
L
N
Y
G
S
H
T
G
D
A
Site 50
S772
G
N
F
L
N
Y
G
S
H
T
G
D
A
D
G
Site 51
S783
D
A
D
G
F
K
I
S
T
L
L
K
L
T
E
Site 52
T789
I
S
T
L
L
K
L
T
E
T
K
S
Q
Q
N
Site 53
S793
L
K
L
T
E
T
K
S
Q
Q
N
R
V
T
L
Site 54
T799
K
S
Q
Q
N
R
V
T
L
L
H
H
V
L
E
Site 55
S811
V
L
E
E
A
E
K
S
H
P
D
L
L
Q
L
Site 56
S826
P
R
D
L
E
Q
P
S
Q
A
A
G
I
N
L
Site 57
S838
I
N
L
E
I
I
R
S
E
A
S
S
N
L
K
Site 58
S842
I
I
R
S
E
A
S
S
N
L
K
K
L
L
E
Site 59
T850
Q
L
S
Q
A
L
D
T
S
N
V
M
V
K
K
Site 60
S855
L
E
T
E
R
K
V
S
A
S
V
A
E
V
Q
Site 61
S857
T
E
R
K
V
S
A
S
V
A
E
V
Q
E
Q
Site 62
S874
E
R
L
Q
A
S
I
S
A
F
R
A
L
D
E
Site 63
Y896
K
Q
R
E
L
A
D
Y
L
C
E
D
A
Q
Q
Site 64
S905
C
E
D
A
Q
Q
L
S
L
E
D
T
F
S
T
Site 65
T909
Q
Q
L
S
L
E
D
T
F
S
T
M
K
A
F
Site 66
S911
L
S
L
E
D
T
F
S
T
M
K
A
F
R
D
Site 67
T989
K
G
F
Q
L
R
K
T
A
R
G
R
G
D
T
Site 68
T996
T
A
R
G
R
G
D
T
D
G
G
S
K
A
A
Site 69
S1000
R
G
D
T
D
G
G
S
K
A
A
S
M
D
P
Site 70
S1004
D
G
G
S
K
A
A
S
M
D
P
P
R
A
T
Site 71
T1011
S
M
D
P
P
R
A
T
E
P
V
A
T
S
N
Site 72
T1016
R
A
T
E
P
V
A
T
S
N
P
A
G
D
P
Site 73
S1026
P
A
G
D
P
V
G
S
T
R
C
P
A
S
E
Site 74
T1027
A
G
D
P
V
G
S
T
R
C
P
A
S
E
P
Site 75
S1032
G
S
T
R
C
P
A
S
E
P
G
L
D
A
T
Site 76
T1039
S
E
P
G
L
D
A
T
T
A
S
E
S
R
G
Site 77
T1040
E
P
G
L
D
A
T
T
A
S
E
S
R
G
W
Site 78
S1042
G
L
D
A
T
T
A
S
E
S
R
G
W
D
L
Site 79
T1054
W
D
L
V
D
A
V
T
P
G
P
Q
P
T
L
Site 80
S1076
P
R
P
L
E
R
R
S
S
W
Y
V
D
A
S
Site 81
S1077
R
P
L
E
R
R
S
S
W
Y
V
D
A
S
D
Site 82
Y1079
L
E
R
R
S
S
W
Y
V
D
A
S
D
V
L
Site 83
S1083
S
S
W
Y
V
D
A
S
D
V
L
T
T
E
D
Site 84
T1087
V
D
A
S
D
V
L
T
T
E
D
P
Q
C
P
Site 85
S1118
L
K
P
L
K
F
S
S
N
Q
P
P
A
A
G
Site 86
S1126
N
Q
P
P
A
A
G
S
S
R
Q
D
A
K
D
Site 87
S1136
Q
D
A
K
D
P
T
S
L
L
G
V
L
Q
A
Site 88
S1147
V
L
Q
A
E
A
D
S
T
S
E
G
L
E
D
Site 89
T1148
L
Q
A
E
A
D
S
T
S
E
G
L
E
D
A
Site 90
S1149
Q
A
E
A
D
S
T
S
E
G
L
E
D
A
V
Site 91
S1158
G
L
E
D
A
V
H
S
R
G
A
R
P
P
A
Site 92
T1179
E
D
E
D
E
E
D
T
A
P
E
S
A
L
D
Site 93
S1183
E
E
D
T
A
P
E
S
A
L
D
T
S
L
D
Site 94
T1187
A
P
E
S
A
L
D
T
S
L
D
K
S
F
S
Site 95
S1188
P
E
S
A
L
D
T
S
L
D
K
S
F
S
E
Site 96
S1192
L
D
T
S
L
D
K
S
F
S
E
D
A
V
T
Site 97
S1194
T
S
L
D
K
S
F
S
E
D
A
V
T
D
S
Site 98
T1199
S
F
S
E
D
A
V
T
D
S
S
G
S
G
T
Site 99
S1201
S
E
D
A
V
T
D
S
S
G
S
G
T
L
P
Site 100
S1202
E
D
A
V
T
D
S
S
G
S
G
T
L
P
R
Site 101
S1204
A
V
T
D
S
S
G
S
G
T
L
P
R
A
R
Site 102
T1206
T
D
S
S
G
S
G
T
L
P
R
A
R
G
R
Site 103
S1215
P
R
A
R
G
R
A
S
K
G
T
G
K
R
R
Site 104
T1218
R
G
R
A
S
K
G
T
G
K
R
R
K
K
R
Site 105
S1227
K
R
R
K
K
R
P
S
R
S
Q
E
E
V
P
Site 106
S1229
R
K
K
R
P
S
R
S
Q
E
G
L
R
P
R
Site 107
S1237
Q
E
E
V
P
P
D
S
D
D
N
K
T
K
K
Site 108
T1242
P
D
S
D
D
N
K
T
K
K
L
C
V
I
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation