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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF630
Full Name:
Zinc finger protein 630
Alias:
BC037316; dJ54B20.2; FLJ20573; MGC138344; ZN630
Type:
Unknown function
Mass (Da):
76094
Number AA:
657
UniProt ID:
Q2M218
International Prot ID:
IPI00719191
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
I
E
S
Q
E
P
V
T
F
E
D
V
A
V
D
Site 2
T18
E
D
V
A
V
D
F
T
Q
E
E
W
Q
Q
L
Site 3
T31
Q
L
N
P
A
Q
K
T
L
H
R
D
V
M
L
Site 4
Y41
R
D
V
M
L
E
T
Y
N
H
L
V
S
V
G
Site 5
S46
E
T
Y
N
H
L
V
S
V
G
C
S
G
I
K
Site 6
Y78
S
E
L
S
R
W
I
Y
P
D
R
V
K
G
L
Site 7
S88
R
V
K
G
L
E
S
S
Q
Q
I
I
S
G
E
Site 8
S111
E
R
A
P
K
D
N
S
L
Y
S
V
L
K
I
Site 9
Y113
A
P
K
D
N
S
L
Y
S
V
L
K
I
W
H
Site 10
Y128
I
D
N
Q
M
D
R
Y
Q
G
N
Q
D
R
V
Site 11
T140
D
R
V
L
R
Q
V
T
V
I
S
R
E
T
L
Site 12
T146
V
T
V
I
S
R
E
T
L
T
D
E
M
G
S
Site 13
T148
V
I
S
R
E
T
L
T
D
E
M
G
S
K
Y
Site 14
Y155
T
D
E
M
G
S
K
Y
S
A
F
G
K
M
F
Site 15
T166
G
K
M
F
N
R
C
T
D
L
A
P
L
S
Q
Site 16
S172
C
T
D
L
A
P
L
S
Q
K
F
H
K
F
D
Site 17
S180
Q
K
F
H
K
F
D
S
C
E
N
S
L
K
S
Site 18
S184
K
F
D
S
C
E
N
S
L
K
S
N
S
D
L
Site 19
S187
S
C
E
N
S
L
K
S
N
S
D
L
L
N
Y
Site 20
Y194
S
N
S
D
L
L
N
Y
N
R
S
Y
A
R
K
Site 21
S197
D
L
L
N
Y
N
R
S
Y
A
R
K
N
P
T
Site 22
Y198
L
L
N
Y
N
R
S
Y
A
R
K
N
P
T
K
Site 23
T204
S
Y
A
R
K
N
P
T
K
R
F
R
C
G
R
Site 24
Y215
R
C
G
R
P
P
K
Y
N
A
S
C
S
V
P
Site 25
S218
R
P
P
K
Y
N
A
S
C
S
V
P
E
K
E
Site 26
S220
P
K
Y
N
A
S
C
S
V
P
E
K
E
G
F
Site 27
S238
G
M
E
P
Y
G
D
S
Q
C
E
K
V
L
S
Site 28
S245
S
Q
C
E
K
V
L
S
H
K
Q
A
H
V
Q
Site 29
S276
G
K
A
F
I
K
K
S
Q
L
I
I
H
Q
R
Site 30
T286
I
I
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 31
Y291
I
H
T
G
E
K
P
Y
V
C
G
D
C
R
K
Site 32
S301
G
D
C
R
K
A
F
S
E
K
S
H
L
I
V
Site 33
S304
R
K
A
F
S
E
K
S
H
L
I
V
H
Q
R
Site 34
T314
I
V
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 35
Y319
I
H
T
G
E
K
P
Y
E
C
T
K
Y
G
R
Site 36
Y324
K
P
Y
E
C
T
K
Y
G
R
A
F
S
R
K
Site 37
S329
T
K
Y
G
R
A
F
S
R
K
S
P
F
T
V
Site 38
S332
G
R
A
F
S
R
K
S
P
F
T
V
H
Q
R
Site 39
T335
F
S
R
K
S
P
F
T
V
H
Q
R
V
H
T
Site 40
T342
T
V
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 41
Y347
V
H
T
G
E
K
P
Y
E
C
F
E
C
P
K
Site 42
S357
F
E
C
P
K
A
F
S
Q
K
S
H
L
I
I
Site 43
S360
P
K
A
F
S
Q
K
S
H
L
I
I
H
Q
R
Site 44
T370
I
I
H
Q
R
V
H
T
R
E
K
P
F
E
C
Site 45
Y403
T
H
T
G
K
K
P
Y
E
C
T
E
C
G
K
Site 46
T406
G
K
K
P
Y
E
C
T
E
C
G
K
T
F
P
Site 47
T411
E
C
T
E
C
G
K
T
F
P
R
K
T
Q
L
Site 48
T416
G
K
T
F
P
R
K
T
Q
L
I
I
H
Q
R
Site 49
T424
Q
L
I
I
H
Q
R
T
H
T
G
E
K
P
Y
Site 50
T426
I
I
H
Q
R
T
H
T
G
E
K
P
Y
K
C
Site 51
Y431
T
H
T
G
E
K
P
Y
K
C
G
E
C
G
K
Site 52
T454
I
G
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 53
Y459
I
H
T
G
E
K
P
Y
V
C
T
D
C
G
K
Site 54
S469
T
D
C
G
K
A
F
S
Q
K
S
H
L
T
G
Site 55
S472
G
K
A
F
S
Q
K
S
H
L
T
G
H
Q
R
Site 56
T482
T
G
H
Q
R
L
H
T
G
E
K
P
Y
M
C
Site 57
Y487
L
H
T
G
E
K
P
Y
M
C
T
E
C
G
K
Site 58
T490
G
E
K
P
Y
M
C
T
E
C
G
K
S
F
S
Site 59
S495
M
C
T
E
C
G
K
S
F
S
Q
K
S
P
L
Site 60
S497
T
E
C
G
K
S
F
S
Q
K
S
P
L
I
I
Site 61
S500
G
K
S
F
S
Q
K
S
P
L
I
I
H
Q
R
Site 62
T510
I
I
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 63
Y515
I
H
T
G
E
K
P
Y
Q
C
G
E
C
G
K
Site 64
T523
Q
C
G
E
C
G
K
T
F
S
Q
K
S
L
L
Site 65
S528
G
K
T
F
S
Q
K
S
L
L
I
I
H
L
R
Site 66
T538
I
I
H
L
R
V
H
T
G
E
K
P
Y
E
C
Site 67
Y543
V
H
T
G
E
K
P
Y
E
C
T
E
C
G
R
Site 68
S556
G
R
A
F
S
L
K
S
H
L
I
L
H
Q
R
Site 69
T566
I
L
H
Q
R
G
H
T
G
E
K
P
Y
E
C
Site 70
Y571
G
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 71
S584
G
K
A
F
C
G
K
S
P
L
I
I
H
Q
K
Site 72
T592
P
L
I
I
H
Q
K
T
H
P
R
E
K
T
P
Site 73
T598
K
T
H
P
R
E
K
T
P
E
C
A
E
S
G
Site 74
Y617
W
K
S
Q
M
I
T
Y
Q
R
R
H
T
G
E
Site 75
T622
I
T
Y
Q
R
R
H
T
G
E
K
P
S
R
C
Site 76
S627
R
H
T
G
E
K
P
S
R
C
S
D
C
G
K
Site 77
S630
G
E
K
P
S
R
C
S
D
C
G
K
A
F
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation