PhosphoNET

           
Protein Info 
   
Short Name:  SPHK1IP
Full Name:  A-kinase anchor protein SPHKAP
Alias:  SKIP; Sphingosine kinase type 1-interacting; Sphingosine kinase type 1-interacting protein; SPHK1 (sphingosine kinase type 1) interacting; SPHK1 interactor, AKAP domain containing; SPHK1-interactor and AKAP domain-containing protein
Type: 
Mass (Da):  186456
Number AA:  1700
UniProt ID:  Q2M3C7
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MDGNSLLSVPSNLES
Site 2S11NSLLSVPSNLESSRM
Site 3S15SVPSNLESSRMYDVL
Site 4Y19NLESSRMYDVLEPQQ
Site 5S32QQGRGCGSSGSGPGN
Site 6S33QGRGCGSSGSGPGNS
Site 7S35RGCGSSGSGPGNSIT
Site 8S40SGSGPGNSITACKKV
Site 9T42SGPGNSITACKKVLR
Site 10S52KKVLRSNSLLESTDY
Site 11S56RSNSLLESTDYWLQN
Site 12Y59SLLESTDYWLQNQRM
Site 13S96DVNKDECSTEHLQQK
Site 14S108QQKLVNVSPDLPKLI
Site 15S116PDLPKLISSMNVQQP
Site 16S167ARGNRPNSTNCIIFE
Site 17T168RGNRPNSTNCIIFEI
Site 18T203ILKLEDDTNCSLSSI
Site 19S206LEDDTNCSLSSIEED
Site 20S208DDTNCSLSSIEEDFL
Site 21T216SIEEDFLTASEHLEE
Site 22S218EEDFLTASEHLEEES
Site 23S225SEHLEEESEVDESRN
Site 24S230EESEVDESRNDYENI
Site 25Y234VDESRNDYENINVSA
Site 26Y266CNKEKWLYALEDKYI
Site 27Y272LYALEDKYINKYPTP
Site 28Y276EDKYINKYPTPLIKT
Site 29T278KYINKYPTPLIKTER
Site 30T283YPTPLIKTERSPENL
Site 31S286PLIKTERSPENLTKN
Site 32T291ERSPENLTKNTALQS
Site 33S298TKNTALQSLDPSAKP
Site 34S302ALQSLDPSAKPSQWK
Site 35S306LDPSAKPSQWKREAV
Site 36T320VGNGRQATHYYHSEA
Site 37Y322NGRQATHYYHSEAFK
Site 38Y323GRQATHYYHSEAFKG
Site 39S335FKGQMEKSQALYIPK
Site 40Y339MEKSQALYIPKDAYF
Site 41Y345LYIPKDAYFSMMDKD
Site 42T374NPGDHEDTRNALPPR
Site 43S398YATNLAESVLQDAFI
Site 44S408QDAFIRLSQSQSTLP
Site 45S410AFIRLSQSQSTLPQE
Site 46S412IRLSQSQSTLPQESA
Site 47S418QSTLPQESAVSVSVG
Site 48S431VGSSLLPSCYSTKDT
Site 49S434SLLPSCYSTKDTVVS
Site 50T435LLPSCYSTKDTVVSR
Site 51T438SCYSTKDTVVSRSWN
Site 52S443KDTVVSRSWNELPKI
Site 53S455PKIVVVQSPDGSDAA
Site 54S459VVQSPDGSDAAPQPG
Site 55S468AAPQPGISSWPEMEV
Site 56S469APQPGISSWPEMEVS
Site 57S476SWPEMEVSVETSSIL
Site 58S480MEVSVETSSILSGEN
Site 59S484VETSSILSGENSSRQ
Site 60S488SILSGENSSRQPQSA
Site 61S489ILSGENSSRQPQSAL
Site 62S494NSSRQPQSALEVALA
Site 63T509CAATVIGTISSPQAT
Site 64S512TVIGTISSPQATERL
Site 65T516TISSPQATERLKMEQ
Site 66S526LKMEQVVSNFPPGSS
Site 67S532VSNFPPGSSGALQTQ
Site 68T538GSSGALQTQAPQGLK
Site 69Y552KEPSINEYSFPSALC
Site 70S553EPSINEYSFPSALCG
Site 71T580LGEREEVTCSVAPSG
Site 72S582EREEVTCSVAPSGSL
Site 73T632LVLTRPNTYSSIGDF
Site 74S634LTRPNTYSSIGDFLD
Site 75S635TRPNTYSSIGDFLDS
Site 76S642SIGDFLDSMNRRIME
Site 77T650MNRRIMETASKSQTL
Site 78S652RRIMETASKSQTLCS
Site 79S654IMETASKSQTLCSEN
Site 80T656ETASKSQTLCSENVV
Site 81S672NELAHTLSNVILRHS
Site 82S679SNVILRHSIDEVHHK
Site 83S698DPNDNRHSSEILDTL
Site 84S699PNDNRHSSEILDTLM
Site 85T704HSSEILDTLMESTNQ
Site 86T747ETIRRRETEPSCQPS
Site 87S750RRRETEPSCQPSDPG
Site 88S754TEPSCQPSDPGASQA
Site 89T763PGASQAWTKATESSS
Site 90T766SQAWTKATESSSSSP
Site 91S768AWTKATESSSSSPLS
Site 92S769WTKATESSSSSPLSN
Site 93S770TKATESSSSSPLSNS
Site 94S771KATESSSSSPLSNSH
Site 95S772ATESSSSSPLSNSHN
Site 96S775SSSSSPLSNSHNTSL
Site 97S777SSSPLSNSHNTSLVI
Site 98Y792NNLVDGMYSKQDKGG
Site 99S793NLVDGMYSKQDKGGV
Site 100T809PGLFKNPTLQSQLSR
Site 101S812FKNPTLQSQLSRSHR
Site 102S815PTLQSQLSRSHRVPD
Site 103S817LQSQLSRSHRVPDSS
Site 104S823RSHRVPDSSTATTSS
Site 105S824SHRVPDSSTATTSSK
Site 106T825HRVPDSSTATTSSKE
Site 107T827VPDSSTATTSSKEIY
Site 108T828PDSSTATTSSKEIYL
Site 109S830SSTATTSSKEIYLKG
Site 110Y834TTSSKEIYLKGIAGE
Site 111T843KGIAGEDTKSPHHSE
Site 112S845IAGEDTKSPHHSENE
Site 113S849DTKSPHHSENECRAS
Site 114S856SENECRASSEGQRSP
Site 115S857ENECRASSEGQRSPT
Site 116S862ASSEGQRSPTVSQSR
Site 117T864SEGQRSPTVSQSRSG
Site 118S866GQRSPTVSQSRSGSQ
Site 119S868RSPTVSQSRSGSQEA
Site 120S870PTVSQSRSGSQEAEE
Site 121S872VSQSRSGSQEAEESI
Site 122S878GSQEAEESIHPNTQE
Site 123T883EESIHPNTQEKYNCA
Site 124Y887HPNTQEKYNCATSRI
Site 125S914DLLLPAQSTLQTKHP
Site 126T915LLLPAQSTLQTKHPD
Site 127T918PAQSTLQTKHPDIYC
Site 128Y924QTKHPDIYCITDFAE
Site 129T971RGSEFLMTPNVPCRS
Site 130S978TPNVPCRSLKRKKES
Site 131S985SLKRKKESQGSGTAV
Site 132S988RKKESQGSGTAVRKH
Site 133S1001KHKPPRLSEIKRKTD
Site 134T1007LSEIKRKTDEHPELK
Site 135S1025MNRVVDESMNLEDVP
Site 136S1034NLEDVPDSVNLFANE
Site 137Y1064GMWQAQGYPRNRLLS
Site 138S1071YPRNRLLSGDRWSRL
Site 139S1076LLSGDRWSRLKASSC
Site 140S1081RWSRLKASSCESIPE
Site 141S1082WSRLKASSCESIPEE
Site 142S1085LKASSCESIPEEDSE
Site 143S1091ESIPEEDSEARAYVN
Site 144Y1096EDSEARAYVNSLGLM
Site 145T1105NSLGLMSTLSQPVSR
Site 146S1111STLSQPVSRASSVSK
Site 147S1114SQPVSRASSVSKQSS
Site 148S1115QPVSRASSVSKQSSC
Site 149S1117VSRASSVSKQSSCES
Site 150S1120ASSVSKQSSCESITD
Site 151S1121SSVSKQSSCESITDE
Site 152S1124SKQSSCESITDEFSR
Site 153T1126QSSCESITDEFSRFM
Site 154Y1150GFELLLDYYAGKNAS
Site 155Y1151FELLLDYYAGKNASS
Site 156S1158YAGKNASSILNSAMQ
Site 157S1162NASSILNSAMQQACR
Site 158S1171MQQACRKSDHLSVRP
Site 159S1175CRKSDHLSVRPSCPS
Site 160S1179DHLSVRPSCPSKQSS
Site 161S1182SVRPSCPSKQSSTES
Site 162S1185PSCPSKQSSTESITE
Site 163S1186SCPSKQSSTESITEE
Site 164S1189SKQSSTESITEEFYR
Site 165T1191QSSTESITEEFYRYM
Site 166Y1197ITEEFYRYMLRDIER
Site 167S1206LRDIERDSRESASSR
Site 168S1209IERDSRESASSRRSS
Site 169S1211RDSRESASSRRSSQD
Site 170S1212DSRESASSRRSSQDW
Site 171S1215ESASSRRSSQDWTAG
Site 172S1216SASSRRSSQDWTAGL
Site 173T1220RRSSQDWTAGLLSPS
Site 174S1225DWTAGLLSPSLRSPV
Site 175S1230LLSPSLRSPVCHRQS
Site 176S1237SPVCHRQSSMPDSRS
Site 177S1238PVCHRQSSMPDSRSP
Site 178S1242RQSSMPDSRSPCSRL
Site 179S1244SSMPDSRSPCSRLTV
Site 180S1247PDSRSPCSRLTVNVP
Site 181T1250RSPCSRLTVNVPIKA
Site 182S1259NVPIKANSLDGFAQN
Site 183S1273NCPQDFLSVQPVSSA
Site 184S1281VQPVSSASSSGLCKS
Site 185S1282QPVSSASSSGLCKSD
Site 186S1283PVSSASSSGLCKSDS
Site 187S1288SSSGLCKSDSCLYRR
Site 188S1290SGLCKSDSCLYRRGG
Site 189Y1293CKSDSCLYRRGGTDH
Site 190T1333DDAEEADTEPVSGGS
Site 191S1337EADTEPVSGGSPSQA
Site 192S1340TEPVSGGSPSQAEKC
Site 193S1342PVSGGSPSQAEKCAN
Site 194S1367PTLLVQESLDCPRKD
Site 195S1375LDCPRKDSVTECKQP
Site 196T1377CPRKDSVTECKQPPV
Site 197S1385ECKQPPVSSLSKTAS
Site 198S1386CKQPPVSSLSKTASL
Site 199S1388QPPVSSLSKTASLTN
Site 200T1390PVSSLSKTASLTNHS
Site 201S1392SSLSKTASLTNHSPL
Site 202T1394LSKTASLTNHSPLDS
Site 203S1397TASLTNHSPLDSKKE
Site 204S1401TNHSPLDSKKETSSC
Site 205T1405PLDSKKETSSCQDPV
Site 206S1406LDSKKETSSCQDPVP
Site 207S1407DSKKETSSCQDPVPI
Site 208S1420PINHKRRSLCSREVP
Site 209S1423HKRRSLCSREVPLIQ
Site 210S1448GEPEPFLSKSSLLEE
Site 211S1450PEPFLSKSSLLEEAE
Site 212S1477RGGDTAVSACQIHSD
Site 213S1485ACQIHSDSLDTRDVP
Site 214S1497DVPEAEASTEARAPD
Site 215S1511DEAPNPPSSSEESTG
Site 216S1512EAPNPPSSSEESTGS
Site 217S1513APNPPSSSEESTGSW
Site 218S1516PPSSSEESTGSWTQL
Site 219T1517PSSSEESTGSWTQLA
Site 220S1519SSEESTGSWTQLANE
Site 221T1533EEDNPDDTSSFLQLS
Site 222S1534EDNPDDTSSFLQLSE
Site 223S1535DNPDDTSSFLQLSER
Site 224S1540TSSFLQLSERSMSNG
Site 225S1543FLQLSERSMSNGNSS
Site 226S1545QLSERSMSNGNSSAT
Site 227S1549RSMSNGNSSATSSLG
Site 228S1550SMSNGNSSATSSLGI
Site 229S1553NGNSSATSSLGIMDL
Site 230S1554GNSSATSSLGIMDLD
Site 231Y1563GIMDLDIYQESMPSS
Site 232S1566DLDIYQESMPSSPMI
Site 233S1570YQESMPSSPMINELV
Site 234S1587KKILKGQSESTEAPA
Site 235T1590LKGQSESTEAPASGP
Site 236S1595ESTEAPASGPPTGTA
Site 237T1599APASGPPTGTASPQR
Site 238T1601ASGPPTGTASPQRSL
Site 239S1603GPPTGTASPQRSLLV
Site 240S1607GTASPQRSLLVINFD
Site 241T1627PDAELRATLQWIAAS
Site 242Y1642ELGIPTIYFKKSQEN
Site 243S1646PTIYFKKSQENRIEK
Site 244Y1678IFHAVVQYCKMHEEQ
Site 245S1691EQKDGRLSLFDWLLE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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