KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF181
Full Name:
Zinc finger protein 181
Alias:
HHZ181
Type:
Mass (Da):
65842
Number AA:
571
UniProt ID:
Q2M3W8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
E
E
W
G
W
L
S
S
A
Q
R
D
L
Y
K
Site 2
Y29
S
S
A
Q
R
D
L
Y
K
D
V
M
V
Q
N
Site 3
Y37
K
D
V
M
V
Q
N
Y
E
N
L
V
S
V
A
Site 4
S88
R
W
E
N
K
E
L
S
T
K
K
D
N
Y
D
Site 5
Y94
L
S
T
K
K
D
N
Y
D
E
D
S
P
Q
T
Site 6
S98
K
D
N
Y
D
E
D
S
P
Q
T
V
I
I
E
Site 7
S111
I
E
K
V
V
K
Q
S
Y
E
F
S
N
S
K
Site 8
Y112
E
K
V
V
K
Q
S
Y
E
F
S
N
S
K
K
Site 9
S115
V
K
Q
S
Y
E
F
S
N
S
K
K
N
L
E
Site 10
S117
Q
S
Y
E
F
S
N
S
K
K
N
L
E
Y
I
Site 11
S133
K
L
E
G
K
H
G
S
Q
V
D
H
F
R
P
Site 12
T144
H
F
R
P
A
I
L
T
S
R
E
S
P
T
A
Site 13
S145
F
R
P
A
I
L
T
S
R
E
S
P
T
A
D
Site 14
S148
A
I
L
T
S
R
E
S
P
T
A
D
S
V
Y
Site 15
S153
R
E
S
P
T
A
D
S
V
Y
K
Y
N
I
F
Site 16
Y155
S
P
T
A
D
S
V
Y
K
Y
N
I
F
R
S
Site 17
Y157
T
A
D
S
V
Y
K
Y
N
I
F
R
S
T
F
Site 18
T163
K
Y
N
I
F
R
S
T
F
H
S
K
S
T
L
Site 19
S166
I
F
R
S
T
F
H
S
K
S
T
L
S
E
P
Site 20
S168
R
S
T
F
H
S
K
S
T
L
S
E
P
Q
K
Site 21
S171
F
H
S
K
S
T
L
S
E
P
Q
K
I
S
A
Site 22
Y185
A
E
G
N
S
H
K
Y
D
I
L
K
K
N
L
Site 23
S196
K
K
N
L
P
K
K
S
V
I
K
N
E
K
V
Site 24
S212
G
G
K
K
L
L
N
S
N
K
S
G
A
A
F
Site 25
S215
K
L
L
N
S
N
K
S
G
A
A
F
S
Q
G
Site 26
S220
N
K
S
G
A
A
F
S
Q
G
K
S
L
T
L
Site 27
S224
A
A
F
S
Q
G
K
S
L
T
L
P
Q
T
C
Site 28
T226
F
S
Q
G
K
S
L
T
L
P
Q
T
C
N
R
Site 29
T230
K
S
L
T
L
P
Q
T
C
N
R
E
K
I
Y
Site 30
Y237
T
C
N
R
E
K
I
Y
T
C
S
E
C
G
K
Site 31
T260
N
R
H
W
R
I
H
T
G
E
K
P
Y
E
C
Site 32
Y265
I
H
T
G
E
K
P
Y
E
C
R
E
C
G
K
Site 33
T273
E
C
R
E
C
G
K
T
F
S
H
G
S
S
L
Site 34
S275
R
E
C
G
K
T
F
S
H
G
S
S
L
T
R
Site 35
S279
K
T
F
S
H
G
S
S
L
T
R
H
L
I
S
Site 36
T281
F
S
H
G
S
S
L
T
R
H
L
I
S
H
S
Site 37
S286
S
L
T
R
H
L
I
S
H
S
G
E
K
P
Y
Site 38
S288
T
R
H
L
I
S
H
S
G
E
K
P
Y
K
C
Site 39
Y293
S
H
S
G
E
K
P
Y
K
C
I
E
C
G
K
Site 40
S303
I
E
C
G
K
A
F
S
H
V
S
S
L
T
N
Site 41
S307
K
A
F
S
H
V
S
S
L
T
N
H
Q
S
T
Site 42
T309
F
S
H
V
S
S
L
T
N
H
Q
S
T
H
T
Site 43
Y321
T
H
T
G
E
K
P
Y
E
C
M
N
C
G
K
Site 44
S329
E
C
M
N
C
G
K
S
F
S
R
V
S
H
L
Site 45
S331
M
N
C
G
K
S
F
S
R
V
S
H
L
I
E
Site 46
S334
G
K
S
F
S
R
V
S
H
L
I
E
H
L
R
Site 47
T344
I
E
H
L
R
I
H
T
Q
E
K
L
Y
E
C
Site 48
Y349
I
H
T
Q
E
K
L
Y
E
C
R
I
C
G
K
Site 49
S362
G
K
A
F
I
H
R
S
S
L
I
H
H
Q
K
Site 50
S363
K
A
F
I
H
R
S
S
L
I
H
H
Q
K
I
Site 51
T372
I
H
H
Q
K
I
H
T
G
E
K
P
Y
E
C
Site 52
T400
T
R
H
Q
R
I
H
T
M
E
K
Q
Y
E
C
Site 53
Y405
I
H
T
M
E
K
Q
Y
E
C
N
K
C
L
K
Site 54
S425
S
F
L
V
Q
H
Q
S
I
H
T
E
E
K
P
Site 55
S441
E
C
Q
K
C
R
K
S
F
N
Q
L
E
S
L
Site 56
S447
K
S
F
N
Q
L
E
S
L
N
M
H
L
R
N
Site 57
Y461
N
H
I
R
L
K
P
Y
E
C
S
I
C
G
K
Site 58
S464
R
L
K
P
Y
E
C
S
I
C
G
K
A
F
S
Site 59
S471
S
I
C
G
K
A
F
S
H
R
S
S
L
L
Q
Site 60
S474
G
K
A
F
S
H
R
S
S
L
L
Q
H
H
R
Site 61
S475
K
A
F
S
H
R
S
S
L
L
Q
H
H
R
I
Site 62
T484
L
Q
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 63
Y489
I
H
T
G
E
K
P
Y
E
C
I
K
C
G
K
Site 64
T497
E
C
I
K
C
G
K
T
F
S
C
S
S
N
L
Site 65
S501
C
G
K
T
F
S
C
S
S
N
L
T
V
H
Q
Site 66
S502
G
K
T
F
S
C
S
S
N
L
T
V
H
Q
R
Site 67
T505
F
S
C
S
S
N
L
T
V
H
Q
R
I
H
T
Site 68
T512
T
V
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 69
Y517
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 70
S546
H
N
G
E
K
P
N
S
V
V
S
V
E
K
P
Site 71
S549
E
K
P
N
S
V
V
S
V
E
K
P
L
D
Y
Site 72
Y556
S
V
E
K
P
L
D
Y
M
N
H
Y
T
C
E
Site 73
Y560
P
L
D
Y
M
N
H
Y
T
C
E
K
S
Y
R
Site 74
T561
L
D
Y
M
N
H
Y
T
C
E
K
S
Y
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation