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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF674
Full Name:
Zinc finger protein 674
Alias:
Type:
Mass (Da):
67199
Number AA:
581
UniProt ID:
Q2M3X9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
M
S
Q
E
S
L
T
F
K
D
V
F
V
D
Site 2
T18
K
D
V
F
V
D
F
T
L
E
E
W
Q
Q
L
Site 3
S27
E
E
W
Q
Q
L
D
S
A
Q
K
N
L
Y
R
Site 4
Y33
D
S
A
Q
K
N
L
Y
R
D
V
M
L
E
N
Site 5
Y41
R
D
V
M
L
E
N
Y
S
H
L
V
S
V
G
Site 6
S42
D
V
M
L
E
N
Y
S
H
L
V
S
V
G
H
Site 7
S46
E
N
Y
S
H
L
V
S
V
G
H
L
V
G
K
Site 8
S66
R
L
G
P
G
D
E
S
W
M
A
D
G
G
T
Site 9
T73
S
W
M
A
D
G
G
T
P
V
R
T
C
A
G
Site 10
Y96
V
D
E
Q
I
D
H
Y
K
E
S
Q
D
K
F
Site 11
T114
A
A
F
I
G
K
E
T
L
K
D
E
S
G
Q
Site 12
T134
R
K
I
I
Y
L
N
T
D
F
V
S
V
K
Q
Site 13
S138
Y
L
N
T
D
F
V
S
V
K
Q
R
L
P
K
Site 14
Y146
V
K
Q
R
L
P
K
Y
Y
S
W
E
R
C
S
Site 15
Y147
K
Q
R
L
P
K
Y
Y
S
W
E
R
C
S
K
Site 16
S165
N
F
L
G
Q
N
R
S
Y
V
R
K
K
D
D
Site 17
Y166
F
L
G
Q
N
R
S
Y
V
R
K
K
D
D
G
Site 18
S214
Q
K
Q
A
L
R
K
S
Q
R
S
Q
T
G
E
Site 19
S217
A
L
R
K
S
Q
R
S
Q
T
G
E
K
L
Y
Site 20
T219
R
K
S
Q
R
S
Q
T
G
E
K
L
Y
K
C
Site 21
Y224
S
Q
T
G
E
K
L
Y
K
C
T
E
C
G
K
Site 22
T245
N
L
V
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 23
T247
V
V
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 24
Y252
T
H
T
G
E
K
P
Y
E
C
C
E
C
A
K
Site 25
S265
A
K
A
F
S
Q
K
S
T
L
I
A
H
Q
R
Site 26
T266
K
A
F
S
Q
K
S
T
L
I
A
H
Q
R
T
Site 27
T273
T
L
I
A
H
Q
R
T
H
T
G
E
K
P
Y
Site 28
T275
I
A
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 29
Y280
T
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 30
T288
E
C
S
E
C
G
K
T
F
I
Q
K
S
T
L
Site 31
S293
G
K
T
F
I
Q
K
S
T
L
I
K
H
Q
R
Site 32
T301
T
L
I
K
H
Q
R
T
H
T
G
E
K
P
F
Site 33
T303
I
K
H
Q
R
T
H
T
G
E
K
P
F
V
C
Site 34
Y321
P
K
A
F
K
S
S
Y
H
L
I
R
H
E
K
Site 35
T329
H
L
I
R
H
E
K
T
H
I
R
Q
A
F
Y
Site 36
Y348
C
T
T
S
S
L
I
Y
Q
R
I
H
T
S
E
Site 37
T353
L
I
Y
Q
R
I
H
T
S
E
K
P
Q
C
S
Site 38
S354
I
Y
Q
R
I
H
T
S
E
K
P
Q
C
S
E
Site 39
S360
T
S
E
K
P
Q
C
S
E
H
G
K
A
S
D
Site 40
S366
C
S
E
H
G
K
A
S
D
E
K
P
S
P
T
Site 41
S371
K
A
S
D
E
K
P
S
P
T
K
H
W
R
T
Site 42
T373
S
D
E
K
P
S
P
T
K
H
W
R
T
H
T
Site 43
T378
S
P
T
K
H
W
R
T
H
T
K
E
N
I
Y
Site 44
T380
T
K
H
W
R
T
H
T
K
E
N
I
Y
E
C
Site 45
Y385
T
H
T
K
E
N
I
Y
E
C
S
K
C
G
K
Site 46
S393
E
C
S
K
C
G
K
S
F
R
G
K
S
H
L
Site 47
S398
G
K
S
F
R
G
K
S
H
L
S
V
H
Q
R
Site 48
S401
F
R
G
K
S
H
L
S
V
H
Q
R
I
H
T
Site 49
T408
S
V
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 50
Y413
I
H
T
G
E
K
P
Y
E
C
S
I
C
G
K
Site 51
S416
G
E
K
P
Y
E
C
S
I
C
G
K
T
F
S
Site 52
T421
E
C
S
I
C
G
K
T
F
S
G
K
S
H
L
Site 53
S423
S
I
C
G
K
T
F
S
G
K
S
H
L
S
V
Site 54
S426
G
K
T
F
S
G
K
S
H
L
S
V
H
H
R
Site 55
S429
F
S
G
K
S
H
L
S
V
H
H
R
T
H
T
Site 56
T434
H
L
S
V
H
H
R
T
H
T
G
E
K
P
Y
Site 57
T436
S
V
H
H
R
T
H
T
G
E
K
P
Y
E
C
Site 58
Y441
T
H
T
G
E
K
P
Y
E
C
R
R
C
G
K
Site 59
S454
G
K
A
F
G
E
K
S
T
L
I
V
H
Q
R
Site 60
T464
I
V
H
Q
R
M
H
T
G
E
K
P
Y
K
C
Site 61
Y469
M
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 62
S482
G
K
A
F
S
E
K
S
P
L
I
K
H
Q
R
Site 63
T492
I
K
H
Q
R
I
H
T
G
E
R
P
Y
E
C
Site 64
Y497
I
H
T
G
E
R
P
Y
E
C
T
D
C
K
K
Site 65
T500
G
E
R
P
Y
E
C
T
D
C
K
K
A
F
S
Site 66
S510
K
K
A
F
S
R
K
S
T
L
I
K
H
Q
R
Site 67
T511
K
A
F
S
R
K
S
T
L
I
K
H
Q
R
I
Site 68
T520
I
K
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 69
Y525
I
H
T
G
E
K
P
Y
K
C
S
E
C
G
K
Site 70
S528
G
E
K
P
Y
K
C
S
E
C
G
K
A
F
S
Site 71
S538
G
K
A
F
S
V
K
S
T
L
I
V
H
H
R
Site 72
T539
K
A
F
S
V
K
S
T
L
I
V
H
H
R
T
Site 73
T546
T
L
I
V
H
H
R
T
H
T
G
E
K
P
Y
Site 74
T548
I
V
H
H
R
T
H
T
G
E
K
P
Y
E
C
Site 75
Y553
T
H
T
G
E
K
P
Y
E
C
R
D
C
G
K
Site 76
S563
R
D
C
G
K
A
F
S
G
K
S
T
L
I
K
Site 77
S566
G
K
A
F
S
G
K
S
T
L
I
K
H
Q
R
Site 78
T567
K
A
F
S
G
K
S
T
L
I
K
H
Q
R
S
Site 79
T576
I
K
H
Q
R
S
H
T
G
D
K
N
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation