KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TCTN1
Full Name:
Tectonic-1
Alias:
Type:
Mass (Da):
63570
Number AA:
587
UniProt ID:
Q2MV58
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
V
S
A
Q
T
D
A
T
P
A
V
T
T
E
G
Site 2
S50
A
T
F
G
T
F
P
S
T
R
P
P
G
T
P
Site 3
T51
T
F
G
T
F
P
S
T
R
P
P
G
T
P
R
Site 4
T56
P
S
T
R
P
P
G
T
P
R
A
P
G
P
S
Site 5
S63
T
P
R
A
P
G
P
S
S
G
P
R
P
T
P
Site 6
S64
P
R
A
P
G
P
S
S
G
P
R
P
T
P
V
Site 7
T69
P
S
S
G
P
R
P
T
P
V
T
D
V
A
V
Site 8
S117
V
P
V
V
T
G
D
S
Q
F
C
S
Q
K
A
Site 9
S121
T
G
D
S
Q
F
C
S
Q
K
A
V
I
Y
S
Site 10
S128
S
Q
K
A
V
I
Y
S
L
N
F
T
A
N
P
Site 11
T132
V
I
Y
S
L
N
F
T
A
N
P
P
Q
R
V
Site 12
S163
T
N
Y
K
P
A
L
S
F
I
N
P
E
V
P
Site 13
T177
P
D
E
N
N
F
D
T
L
M
K
T
S
D
G
Site 14
T181
N
F
D
T
L
M
K
T
S
D
G
F
T
L
N
Site 15
T186
M
K
T
S
D
G
F
T
L
N
A
E
S
Y
V
Site 16
S191
G
F
T
L
N
A
E
S
Y
V
S
F
T
T
K
Site 17
Y207
D
I
P
T
A
A
K
Y
E
Y
G
V
P
L
Q
Site 18
Y209
P
T
A
A
K
Y
E
Y
G
V
P
L
Q
T
S
Site 19
S218
V
P
L
Q
T
S
D
S
F
L
R
F
P
S
S
Site 20
S228
R
F
P
S
S
L
T
S
S
L
C
T
D
N
N
Site 21
S229
F
P
S
S
L
T
S
S
L
C
T
D
N
N
P
Site 22
T232
S
L
T
S
S
L
C
T
D
N
N
P
A
A
F
Site 23
S278
E
I
L
R
V
P
D
S
R
K
K
V
P
I
T
Site 24
T297
V
I
Q
S
L
N
K
T
L
T
R
R
E
D
T
Site 25
T299
Q
S
L
N
K
T
L
T
R
R
E
D
T
D
V
Site 26
T304
T
L
T
R
R
E
D
T
D
V
L
Q
P
T
L
Site 27
T310
D
T
D
V
L
Q
P
T
L
V
N
A
G
H
F
Site 28
T334
V
K
Y
S
L
T
Y
T
D
A
G
E
V
T
K
Site 29
S377
N
T
Q
P
V
P
L
S
G
N
P
G
Y
V
V
Site 30
T403
K
G
S
G
I
I
Q
T
T
N
R
Y
G
Q
L
Site 31
T411
T
N
R
Y
G
Q
L
T
I
L
H
S
T
T
E
Site 32
Y435
R
T
P
V
L
F
G
Y
T
M
Q
S
G
C
K
Site 33
Y470
W
G
Q
G
F
P
D
Y
V
A
P
F
G
N
S
Site 34
S500
Q
S
F
N
R
K
D
S
C
Q
L
P
G
A
L
Site 35
Y516
I
E
V
K
W
T
K
Y
G
S
L
L
N
P
Q
Site 36
S537
T
A
N
L
I
S
S
S
F
P
E
A
N
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation