KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CTC1
Full Name:
CST complex subunit CTC1
Alias:
Conserved telomere maintenance component 1;HBV DNAPTP1-transactivated protein B
Type:
Mass (Da):
134609
Number AA:
1217
UniProt ID:
Q2NKJ3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
G
R
A
Q
V
P
S
S
E
Q
A
W
L
E
Site 2
S11
G
R
A
Q
V
P
S
S
E
Q
A
W
L
E
D
Site 3
S52
C
V
K
T
V
W
L
S
Q
G
R
N
Q
G
S
Site 4
S59
S
Q
G
R
N
Q
G
S
T
L
P
L
S
Y
S
Site 5
T60
Q
G
R
N
Q
G
S
T
L
P
L
S
Y
S
F
Site 6
S69
P
L
S
Y
S
F
V
S
V
Q
D
L
K
T
H
Site 7
T75
V
S
V
Q
D
L
K
T
H
Q
R
L
P
C
C
Site 8
S83
H
Q
R
L
P
C
C
S
H
L
S
W
S
S
S
Site 9
S86
L
P
C
C
S
H
L
S
W
S
S
S
A
Y
Q
Site 10
S90
S
H
L
S
W
S
S
S
A
Y
Q
A
W
A
Q
Site 11
Y92
L
S
W
S
S
S
A
Y
Q
A
W
A
Q
E
A
Site 12
S121
L
G
T
L
T
D
L
S
A
D
L
E
Q
E
C
Site 13
S132
E
Q
E
C
R
N
G
S
L
Y
V
R
D
N
T
Site 14
Y134
E
C
R
N
G
S
L
Y
V
R
D
N
T
G
V
Site 15
Y165
F
L
F
P
R
W
S
Y
L
P
P
A
R
W
N
Site 16
S173
L
P
P
A
R
W
N
S
S
G
E
G
H
L
E
Site 17
Y244
V
K
S
K
Q
K
A
Y
F
I
L
S
L
G
R
Site 18
S248
Q
K
A
Y
F
I
L
S
L
G
R
S
H
P
A
Site 19
T279
H
R
A
L
R
P
G
T
A
Y
V
L
T
E
L
Site 20
S289
V
L
T
E
L
R
V
S
K
I
R
G
Q
R
Q
Site 21
S302
R
Q
H
V
W
M
T
S
Q
S
S
R
L
L
L
Site 22
S304
H
V
W
M
T
S
Q
S
S
R
L
L
L
L
K
Site 23
S338
P
K
P
L
P
M
P
S
N
S
E
D
K
K
D
Site 24
S340
P
L
P
M
P
S
N
S
E
D
K
K
D
P
E
Site 25
S348
E
D
K
K
D
P
E
S
L
V
R
Y
S
R
L
Site 26
Y352
D
P
E
S
L
V
R
Y
S
R
L
L
S
Y
S
Site 27
S353
P
E
S
L
V
R
Y
S
R
L
L
S
Y
S
G
Site 28
S357
V
R
Y
S
R
L
L
S
Y
S
G
A
V
T
G
Site 29
Y373
L
N
E
P
A
G
L
Y
E
L
D
G
Q
L
G
Site 30
S411
Q
D
V
H
L
L
Q
S
V
G
G
G
T
R
R
Site 31
S433
R
G
A
V
L
L
Q
S
F
S
R
Q
K
P
G
Site 32
S435
A
V
L
L
Q
S
F
S
R
Q
K
P
G
A
H
Site 33
S444
Q
K
P
G
A
H
S
S
R
Q
A
Y
G
A
S
Site 34
Y448
A
H
S
S
R
Q
A
Y
G
A
S
L
Y
E
Q
Site 35
S451
S
R
Q
A
Y
G
A
S
L
Y
E
Q
L
V
W
Site 36
Y453
Q
A
Y
G
A
S
L
Y
E
Q
L
V
W
E
R
Site 37
S495
H
H
Q
F
L
Q
H
S
S
P
G
S
P
S
L
Site 38
S496
H
Q
F
L
Q
H
S
S
P
G
S
P
S
L
G
Site 39
S499
L
Q
H
S
S
P
G
S
P
S
L
G
L
Q
L
Site 40
S501
H
S
S
P
G
S
P
S
L
G
L
Q
L
L
A
Site 41
S519
D
L
L
A
P
P
G
S
P
V
R
N
A
H
N
Site 42
Y540
H
H
C
P
L
Q
K
Y
T
R
L
Q
T
P
S
Site 43
T545
Q
K
Y
T
R
L
Q
T
P
S
S
F
P
T
L
Site 44
S547
Y
T
R
L
Q
T
P
S
S
F
P
T
L
A
T
Site 45
S548
T
R
L
Q
T
P
S
S
F
P
T
L
A
T
L
Site 46
T551
Q
T
P
S
S
F
P
T
L
A
T
L
K
E
E
Site 47
T554
S
S
F
P
T
L
A
T
L
K
E
E
G
Q
R
Site 48
S566
G
Q
R
K
A
W
A
S
F
D
P
K
A
L
L
Site 49
Y580
L
P
L
P
E
A
S
Y
L
P
S
C
Q
L
N
Site 50
S583
P
E
A
S
Y
L
P
S
C
Q
L
N
R
R
L
Site 51
S639
C
L
L
L
A
K
H
S
Q
P
L
S
D
P
R
Site 52
S643
A
K
H
S
Q
P
L
S
D
P
R
L
I
G
C
Site 53
S667
I
V
E
R
D
V
R
S
S
F
P
S
W
K
E
Site 54
S668
V
E
R
D
V
R
S
S
F
P
S
W
K
E
L
Site 55
S671
D
V
R
S
S
F
P
S
W
K
E
L
S
M
P
Site 56
S676
F
P
S
W
K
E
L
S
M
P
G
F
I
Q
K
Site 57
Y689
Q
K
Q
Q
A
R
V
Y
V
Q
F
F
L
A
D
Site 58
S709
V
P
R
P
C
L
H
S
A
T
P
S
T
P
Q
Site 59
T711
R
P
C
L
H
S
A
T
P
S
T
P
Q
T
D
Site 60
S713
C
L
H
S
A
T
P
S
T
P
Q
T
D
P
T
Site 61
T714
L
H
S
A
T
P
S
T
P
Q
T
D
P
T
G
Site 62
T717
A
T
P
S
T
P
Q
T
D
P
T
G
P
E
G
Site 63
T720
S
T
P
Q
T
D
P
T
G
P
E
G
P
H
L
Site 64
S753
F
C
V
P
P
G
A
S
P
E
V
P
K
P
A
Site 65
T773
L
G
S
W
L
G
G
T
Q
R
K
E
G
T
G
Site 66
S835
M
L
F
E
K
D
G
S
S
C
I
S
R
R
P
Site 67
S836
L
F
E
K
D
G
S
S
C
I
S
R
R
P
L
Site 68
S839
K
D
G
S
S
C
I
S
R
R
P
L
E
L
A
Site 69
T859
L
T
V
Q
D
N
W
T
L
E
L
E
S
S
Q
Site 70
S865
W
T
L
E
L
E
S
S
Q
D
I
Q
D
V
L
Site 71
S877
D
V
L
D
A
N
K
S
L
P
E
S
S
L
T
Site 72
S881
A
N
K
S
L
P
E
S
S
L
T
D
L
L
S
Site 73
S882
N
K
S
L
P
E
S
S
L
T
D
L
L
S
D
Site 74
T884
S
L
P
E
S
S
L
T
D
L
L
S
D
N
F
Site 75
S888
S
S
L
T
D
L
L
S
D
N
F
T
D
S
L
Site 76
T892
D
L
L
S
D
N
F
T
D
S
L
V
S
F
S
Site 77
S894
L
S
D
N
F
T
D
S
L
V
S
F
S
A
E
Site 78
Y949
F
P
P
H
L
D
V
Y
I
E
D
P
H
L
P
Site 79
S958
E
D
P
H
L
P
P
S
L
G
L
L
P
G
A
Site 80
S970
P
G
A
R
V
H
F
S
Q
L
E
K
R
V
S
Site 81
S977
S
Q
L
E
K
R
V
S
R
S
H
N
V
Y
C
Site 82
Y983
V
S
R
S
H
N
V
Y
C
C
F
R
S
S
T
Site 83
S1021
E
L
L
Q
G
G
Q
S
P
F
Q
A
T
A
S
Site 84
T1056
I
C
R
Q
G
K
C
T
R
L
G
S
T
C
P
Site 85
S1060
G
K
C
T
R
L
G
S
T
C
P
T
Q
T
A
Site 86
T1064
R
L
G
S
T
C
P
T
Q
T
A
I
S
Q
A
Site 87
T1066
G
S
T
C
P
T
Q
T
A
I
S
Q
A
I
I
Site 88
S1131
P
G
A
Q
L
E
S
S
A
R
V
D
E
P
M
Site 89
S1166
F
E
L
E
R
K
P
S
K
I
V
P
L
E
P
Site 90
T1188
C
G
E
L
P
F
L
T
H
V
N
P
R
L
R
Site 91
S1197
V
N
P
R
L
R
L
S
C
L
S
I
R
E
S
Site 92
S1200
R
L
R
L
S
C
L
S
I
R
E
S
E
Y
S
Site 93
S1204
S
C
L
S
I
R
E
S
E
Y
S
S
S
L
G
Site 94
Y1206
L
S
I
R
E
S
E
Y
S
S
S
L
G
I
L
Site 95
S1207
S
I
R
E
S
E
Y
S
S
S
L
G
I
L
A
Site 96
S1208
I
R
E
S
E
Y
S
S
S
L
G
I
L
A
S
Site 97
S1209
R
E
S
E
Y
S
S
S
L
G
I
L
A
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation