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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INTS4L2
Full Name:
Integrator complex subunit 4-like protein 2
Alias:
Type:
Mass (Da):
48884
Number AA:
439
UniProt ID:
Q2T9F4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
P
R
P
A
R
G
C
S
S
A
D
S
S
R
S
Site 2
S19
R
P
A
R
G
C
S
S
A
D
S
S
R
S
S
Site 3
S22
R
G
C
S
S
A
D
S
S
R
S
S
S
A
S
Site 4
S23
G
C
S
S
A
D
S
S
R
S
S
S
A
S
P
Site 5
S25
S
S
A
D
S
S
R
S
S
S
A
S
P
L
A
Site 6
S26
S
A
D
S
S
R
S
S
S
A
S
P
L
A
A
Site 7
S27
A
D
S
S
R
S
S
S
A
S
P
L
A
A
C
Site 8
S29
S
S
R
S
S
S
A
S
P
L
A
A
C
A
G
Site 9
T45
A
P
S
A
L
C
P
T
T
S
P
S
R
R
Y
Site 10
T46
P
S
A
L
C
P
T
T
S
P
S
R
R
Y
G
Site 11
S47
S
A
L
C
P
T
T
S
P
S
R
R
Y
G
P
Site 12
S49
L
C
P
T
T
S
P
S
R
R
Y
G
P
W
S
Site 13
Y52
T
T
S
P
S
R
R
Y
G
P
W
S
I
V
P
Site 14
S56
S
R
R
Y
G
P
W
S
I
V
P
I
P
S
S
Site 15
S104
G
S
M
E
Q
V
S
S
H
F
L
E
Q
T
L
Site 16
T110
S
S
H
F
L
E
Q
T
L
D
K
K
L
M
S
Site 17
S117
T
L
D
K
K
L
M
S
D
L
R
R
K
R
T
Site 18
T124
S
D
L
R
R
K
R
T
A
H
E
R
A
K
E
Site 19
Y133
H
E
R
A
K
E
L
Y
S
S
G
E
F
S
S
Site 20
S134
E
R
A
K
E
L
Y
S
S
G
E
F
S
S
G
Site 21
S135
R
A
K
E
L
Y
S
S
G
E
F
S
S
G
R
Site 22
S139
L
Y
S
S
G
E
F
S
S
G
R
K
W
E
D
Site 23
S140
Y
S
S
G
E
F
S
S
G
R
K
W
E
D
D
Site 24
T155
A
P
K
E
E
V
D
T
G
A
V
N
L
I
E
Site 25
Y178
H
G
L
E
D
E
M
Y
E
V
R
I
A
A
V
Site 26
S197
M
L
A
Q
S
S
P
S
F
A
E
K
C
L
D
Site 27
S221
I
E
E
V
R
L
Q
S
I
H
T
M
R
K
I
Site 28
T224
V
R
L
Q
S
I
H
T
M
R
K
I
S
N
N
Site 29
S229
I
H
T
M
R
K
I
S
N
N
I
T
L
R
E
Site 30
T233
R
K
I
S
N
N
I
T
L
R
E
D
Q
L
D
Site 31
T241
L
R
E
D
Q
L
D
T
V
L
A
V
L
E
D
Site 32
T284
V
E
L
L
K
N
L
T
K
Y
P
T
D
R
D
Site 33
Y286
L
L
K
N
L
T
K
Y
P
T
D
R
D
S
I
Site 34
T288
K
N
L
T
K
Y
P
T
D
R
D
S
I
W
K
Site 35
T324
S
T
H
P
F
F
D
T
A
E
P
D
M
D
D
Site 36
T350
N
A
A
K
T
C
P
T
M
R
A
L
F
S
D
Site 37
T359
R
A
L
F
S
D
H
T
V
R
H
Y
A
Y
L
Site 38
Y363
S
D
H
T
V
R
H
Y
A
Y
L
R
D
S
L
Site 39
Y365
H
T
V
R
H
Y
A
Y
L
R
D
S
L
S
H
Site 40
S369
H
Y
A
Y
L
R
D
S
L
S
H
L
V
P
A
Site 41
S392
V
S
S
A
V
S
P
S
I
I
P
Q
E
D
P
Site 42
S400
I
I
P
Q
E
D
P
S
Q
Q
F
L
Q
Q
S
Site 43
S407
S
Q
Q
F
L
Q
Q
S
L
E
R
V
Y
S
L
Site 44
Y412
Q
Q
S
L
E
R
V
Y
S
L
Q
H
L
D
P
Site 45
S413
Q
S
L
E
R
V
Y
S
L
Q
H
L
D
P
Q
Site 46
T429
A
Q
E
L
L
E
F
T
I
R
P
C
R
K
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation