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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATG2A
Full Name:
Autophagy-related protein 2 homolog A
Alias:
ATG2 autophagy related 2 A; KIAA0404
Type:
Autophagy
Mass (Da):
212901
Number AA:
1938
UniProt ID:
Q2TAZ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Autophagy-related protein 2 homologue A pan-specific antibody AB-NN209-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN209-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
V
K
E
R
V
C
R
Y
L
L
H
H
Y
L
G
Site 2
Y24
C
R
Y
L
L
H
H
Y
L
G
H
F
F
Q
E
Site 3
S34
H
F
F
Q
E
H
L
S
L
D
Q
L
S
L
D
Site 4
S39
H
L
S
L
D
Q
L
S
L
D
L
Y
K
G
S
Site 5
Y43
D
Q
L
S
L
D
L
Y
K
G
S
V
A
L
R
Site 6
S58
D
I
H
L
E
I
W
S
V
N
E
V
L
E
S
Site 7
S65
S
V
N
E
V
L
E
S
M
E
S
P
L
E
L
Site 8
S68
E
V
L
E
S
M
E
S
P
L
E
L
V
E
G
Site 9
T104
R
V
S
G
L
Q
L
T
L
Q
P
R
R
G
P
Site 10
S118
P
A
P
G
A
A
D
S
Q
S
W
A
S
C
M
Site 11
S120
P
G
A
A
D
S
Q
S
W
A
S
C
M
T
T
Site 12
T127
S
W
A
S
C
M
T
T
S
L
Q
L
A
Q
E
Site 13
S144
R
D
G
L
P
E
P
S
E
P
P
Q
P
L
E
Site 14
S181
T
V
V
R
V
E
H
S
P
G
D
G
E
R
G
Site 15
Y200
V
R
V
Q
R
L
E
Y
C
D
E
A
V
R
D
Site 16
S209
D
E
A
V
R
D
P
S
Q
A
P
P
V
D
V
Site 17
Y236
L
A
G
V
R
L
H
Y
E
E
L
P
A
Q
E
Site 18
S254
E
P
P
L
Q
I
G
S
C
S
G
Y
M
E
L
Site 19
Y258
Q
I
G
S
C
S
G
Y
M
E
L
M
V
K
L
Site 20
T290
G
S
L
H
L
L
L
T
P
R
Q
L
Q
Q
L
Site 21
S302
Q
Q
L
Q
E
L
L
S
A
V
S
L
T
D
H
Site 22
S305
Q
E
L
L
S
A
V
S
L
T
D
H
E
G
L
Site 23
S319
L
A
D
K
L
N
K
S
R
P
L
G
A
E
D
Site 24
S348
G
A
V
A
E
P
L
S
P
D
P
L
T
N
P
Site 25
T353
P
L
S
P
D
P
L
T
N
P
L
L
N
L
D
Site 26
S367
D
N
T
D
L
F
F
S
M
A
G
L
T
S
S
Site 27
S391
L
S
D
V
D
L
A
S
S
V
R
S
D
M
A
Site 28
S392
S
D
V
D
L
A
S
S
V
R
S
D
M
A
S
Site 29
S395
D
L
A
S
S
V
R
S
D
M
A
S
R
R
L
Site 30
S399
S
V
R
S
D
M
A
S
R
R
L
S
A
Q
A
Site 31
S403
D
M
A
S
R
R
L
S
A
Q
A
H
P
A
G
Site 32
T420
A
P
N
P
L
L
D
T
M
R
P
D
S
L
L
Site 33
S425
L
D
T
M
R
P
D
S
L
L
K
M
T
L
G
Site 34
S442
T
L
T
L
L
Q
T
S
A
P
S
S
G
P
P
Site 35
S446
L
Q
T
S
A
P
S
S
G
P
P
D
L
A
T
Site 36
T453
S
G
P
P
D
L
A
T
H
F
F
T
E
F
D
Site 37
T462
F
F
T
E
F
D
A
T
K
D
G
P
F
G
S
Site 38
S469
T
K
D
G
P
F
G
S
R
D
F
H
H
L
R
Site 39
T493
S
H
V
R
L
T
G
T
A
V
Q
L
S
W
E
Site 40
S498
T
G
T
A
V
Q
L
S
W
E
L
R
T
G
S
Site 41
S505
S
W
E
L
R
T
G
S
R
G
R
R
T
T
S
Site 42
T510
T
G
S
R
G
R
R
T
T
S
M
E
V
H
F
Site 43
T511
G
S
R
G
R
R
T
T
S
M
E
V
H
F
G
Site 44
S512
S
R
G
R
R
T
T
S
M
E
V
H
F
G
Q
Site 45
T531
E
C
L
W
P
R
G
T
S
E
P
E
Y
T
E
Site 46
S532
C
L
W
P
R
G
T
S
E
P
E
Y
T
E
I
Site 47
Y536
R
G
T
S
E
P
E
Y
T
E
I
L
T
F
P
Site 48
T537
G
T
S
E
P
E
Y
T
E
I
L
T
F
P
G
Site 49
T541
P
E
Y
T
E
I
L
T
F
P
G
T
L
G
S
Site 50
S548
T
F
P
G
T
L
G
S
Q
A
S
A
R
P
C
Site 51
S551
G
T
L
G
S
Q
A
S
A
R
P
C
A
H
L
Site 52
T561
P
C
A
H
L
R
H
T
Q
I
L
R
R
V
P
Site 53
S570
I
L
R
R
V
P
K
S
R
P
R
R
S
V
A
Site 54
S575
P
K
S
R
P
R
R
S
V
A
C
H
C
H
S
Site 55
T632
L
P
A
M
E
Q
Q
T
V
F
R
L
S
A
P
Site 56
S637
Q
Q
T
V
F
R
L
S
A
P
R
A
T
L
R
Site 57
T642
R
L
S
A
P
R
A
T
L
R
L
R
F
P
I
Site 58
S674
E
Q
L
R
L
E
L
S
E
P
Q
F
R
S
E
Site 59
S680
L
S
E
P
Q
F
R
S
E
L
S
S
G
P
G
Site 60
S683
P
Q
F
R
S
E
L
S
S
G
P
G
P
P
V
Site 61
S684
Q
F
R
S
E
L
S
S
G
P
G
P
P
V
P
Site 62
S699
T
H
L
E
L
T
C
S
D
L
H
G
I
Y
E
Site 63
Y705
C
S
D
L
H
G
I
Y
E
D
G
G
K
P
P
Site 64
S719
P
V
P
C
L
R
V
S
K
A
L
D
P
K
S
Site 65
S726
S
K
A
L
D
P
K
S
T
G
R
K
Y
F
L
Site 66
Y731
P
K
S
T
G
R
K
Y
F
L
P
Q
V
V
V
Site 67
S744
V
V
T
V
N
P
Q
S
S
S
T
Q
W
E
V
Site 68
S762
K
G
E
E
L
E
L
S
V
E
S
P
C
E
L
Site 69
S765
E
L
E
L
S
V
E
S
P
C
E
L
R
E
P
Site 70
S775
E
L
R
E
P
E
P
S
P
F
S
S
K
R
T
Site 71
S778
E
P
E
P
S
P
F
S
S
K
R
T
M
Y
E
Site 72
S779
P
E
P
S
P
F
S
S
K
R
T
M
Y
E
T
Site 73
T782
S
P
F
S
S
K
R
T
M
Y
E
T
E
E
M
Site 74
Y784
F
S
S
K
R
T
M
Y
E
T
E
E
M
V
I
Site 75
T786
S
K
R
T
M
Y
E
T
E
E
M
V
I
P
G
Site 76
T800
G
D
P
E
E
M
R
T
F
Q
S
R
T
L
A
Site 77
T805
M
R
T
F
Q
S
R
T
L
A
L
S
R
C
S
Site 78
S809
Q
S
R
T
L
A
L
S
R
C
S
L
E
V
I
Site 79
S812
T
L
A
L
S
R
C
S
L
E
V
I
L
P
S
Site 80
Y830
F
L
P
S
K
E
V
Y
E
S
I
Y
N
R
I
Site 81
Y834
K
E
V
Y
E
S
I
Y
N
R
I
N
N
D
L
Site 82
T852
E
P
A
D
L
L
P
T
P
D
P
A
A
Q
P
Site 83
S860
P
D
P
A
A
Q
P
S
G
F
P
G
P
S
G
Site 84
S866
P
S
G
F
P
G
P
S
G
F
W
H
D
S
F
Site 85
S878
D
S
F
K
M
C
K
S
A
F
K
L
A
N
C
Site 86
T889
L
A
N
C
F
D
L
T
P
D
S
D
S
D
D
Site 87
S892
C
F
D
L
T
P
D
S
D
S
D
D
E
D
A
Site 88
S894
D
L
T
P
D
S
D
S
D
D
E
D
A
H
F
Site 89
S903
D
E
D
A
H
F
F
S
V
G
A
S
G
G
P
Site 90
S919
A
A
A
P
E
A
P
S
L
H
L
Q
S
T
F
Site 91
T938
T
V
L
K
G
R
I
T
A
L
C
E
T
K
D
Site 92
S971
H
G
T
L
F
S
V
S
Q
Y
C
G
Q
P
G
Site 93
Y981
C
G
Q
P
G
L
G
Y
F
C
L
E
A
E
K
Site 94
Y992
E
A
E
K
A
T
L
Y
H
R
A
A
V
D
D
Site 95
Y1000
H
R
A
A
V
D
D
Y
P
L
P
S
H
L
D
Site 96
S1004
V
D
D
Y
P
L
P
S
H
L
D
L
P
S
F
Site 97
S1010
P
S
H
L
D
L
P
S
F
A
P
P
A
Q
L
Site 98
T1020
P
P
A
Q
L
A
P
T
I
Y
P
S
E
E
G
Site 99
Y1022
A
Q
L
A
P
T
I
Y
P
S
E
E
G
V
T
Site 100
S1024
L
A
P
T
I
Y
P
S
E
E
G
V
T
E
R
Site 101
T1029
Y
P
S
E
E
G
V
T
E
R
G
A
S
G
R
Site 102
S1034
G
V
T
E
R
G
A
S
G
R
K
G
Q
G
R
Site 103
S1047
G
R
G
P
H
M
L
S
T
A
V
R
I
H
L
Site 104
T1048
R
G
P
H
M
L
S
T
A
V
R
I
H
L
D
Site 105
T1066
N
V
K
E
F
L
V
T
L
R
L
H
K
A
T
Site 106
T1073
T
L
R
L
H
K
A
T
L
R
H
Y
M
A
L
Site 107
Y1077
H
K
A
T
L
R
H
Y
M
A
L
P
E
Q
S
Site 108
S1166
D
D
S
A
L
Y
L
S
D
K
C
E
V
E
T
Site 109
S1199
V
I
K
T
W
K
G
S
T
E
G
K
L
S
Q
Site 110
S1205
G
S
T
E
G
K
L
S
Q
P
L
F
E
L
R
Site 111
S1239
N
L
L
Q
Y
V
M
S
T
G
D
L
H
P
P
Site 112
S1251
H
P
P
P
R
P
P
S
P
T
E
I
A
G
Q
Site 113
T1253
P
P
R
P
P
S
P
T
E
I
A
G
Q
K
L
Site 114
S1261
E
I
A
G
Q
K
L
S
E
S
P
A
S
L
P
Site 115
S1263
A
G
Q
K
L
S
E
S
P
A
S
L
P
S
C
Site 116
S1266
K
L
S
E
S
P
A
S
L
P
S
C
P
P
V
Site 117
S1269
E
S
P
A
S
L
P
S
C
P
P
V
E
T
A
Site 118
T1290
L
A
D
A
L
L
D
T
E
R
S
L
R
E
L
Site 119
S1293
A
L
L
D
T
E
R
S
L
R
E
L
A
Q
P
Site 120
S1301
L
R
E
L
A
Q
P
S
G
G
H
L
P
Q
A
Site 121
Y1314
Q
A
S
P
I
S
V
Y
L
F
P
G
E
R
S
Site 122
S1321
Y
L
F
P
G
E
R
S
G
A
P
P
P
S
P
Site 123
S1327
R
S
G
A
P
P
P
S
P
P
V
G
G
P
A
Site 124
S1336
P
V
G
G
P
A
G
S
L
G
S
C
S
E
E
Site 125
S1339
G
P
A
G
S
L
G
S
C
S
E
E
K
E
D
Site 126
S1341
A
G
S
L
G
S
C
S
E
E
K
E
D
E
R
Site 127
T1356
E
E
E
G
D
G
D
T
L
D
S
D
E
F
C
Site 128
S1359
G
D
G
D
T
L
D
S
D
E
F
C
I
L
D
Site 129
T1382
R
D
G
E
P
V
V
T
Q
L
H
P
G
P
I
Site 130
Y1395
P
I
V
V
R
D
G
Y
F
S
R
P
I
G
S
Site 131
S1397
V
V
R
D
G
Y
F
S
R
P
I
G
S
T
D
Site 132
S1416
P
A
H
F
P
V
P
S
T
R
V
V
L
R
E
Site 133
T1446
H
P
G
H
R
A
R
T
G
L
S
G
P
R
S
Site 134
S1449
H
R
A
R
T
G
L
S
G
P
R
S
S
P
S
Site 135
S1453
T
G
L
S
G
P
R
S
S
P
S
R
C
S
G
Site 136
S1454
G
L
S
G
P
R
S
S
P
S
R
C
S
G
P
Site 137
S1456
S
G
P
R
S
S
P
S
R
C
S
G
P
N
R
Site 138
S1459
R
S
S
P
S
R
C
S
G
P
N
R
P
Q
N
Site 139
S1467
G
P
N
R
P
Q
N
S
W
R
T
Q
G
G
S
Site 140
T1470
R
P
Q
N
S
W
R
T
Q
G
G
S
G
R
Q
Site 141
S1474
S
W
R
T
Q
G
G
S
G
R
Q
H
H
V
L
Site 142
S1490
E
I
Q
L
S
K
V
S
F
Q
H
E
V
Y
P
Site 143
Y1496
V
S
F
Q
H
E
V
Y
P
A
E
P
A
T
G
Site 144
T1502
V
Y
P
A
E
P
A
T
G
P
A
A
P
S
Q
Site 145
S1517
E
L
E
E
R
P
L
S
R
Q
V
F
I
V
Q
Site 146
S1534
E
V
R
D
R
L
A
S
S
Q
I
N
K
F
L
Site 147
S1535
V
R
D
R
L
A
S
S
Q
I
N
K
F
L
Y
Site 148
Y1542
S
Q
I
N
K
F
L
Y
L
H
T
S
E
R
M
Site 149
S1546
K
F
L
Y
L
H
T
S
E
R
M
P
R
R
A
Site 150
S1555
R
M
P
R
R
A
H
S
N
M
L
T
I
K
A
Site 151
T1624
S
A
E
A
R
P
E
T
R
A
Q
P
S
S
P
Site 152
S1629
P
E
T
R
A
Q
P
S
S
P
L
E
G
Q
A
Site 153
S1630
E
T
R
A
Q
P
S
S
P
L
E
G
Q
A
E
Site 154
T1641
G
Q
A
E
G
V
E
T
T
G
S
Q
E
A
P
Site 155
S1644
E
G
V
E
T
T
G
S
Q
E
A
P
G
G
G
Site 156
S1653
E
A
P
G
G
G
H
S
P
S
P
P
D
Q
Q
Site 157
S1655
P
G
G
G
H
S
P
S
P
P
D
Q
Q
P
I
Site 158
Y1663
P
P
D
Q
Q
P
I
Y
F
R
E
F
R
F
T
Site 159
T1670
Y
F
R
E
F
R
F
T
S
E
V
P
I
W
L
Site 160
S1671
F
R
E
F
R
F
T
S
E
V
P
I
W
L
D
Site 161
Y1772
L
W
L
P
I
E
Q
Y
R
K
D
G
R
L
M
Site 162
S1788
G
L
Q
R
G
A
A
S
F
G
S
S
T
A
S
Site 163
S1795
S
F
G
S
S
T
A
S
A
A
L
E
L
S
N
Site 164
S1820
E
T
V
Y
D
I
L
S
P
A
A
P
V
S
R
Site 165
S1826
L
S
P
A
A
P
V
S
R
S
L
Q
D
K
R
Site 166
S1828
P
A
A
P
V
S
R
S
L
Q
D
K
R
S
A
Site 167
S1834
R
S
L
Q
D
K
R
S
A
R
R
L
R
R
G
Site 168
Y1855
R
E
G
V
A
K
A
Y
D
T
V
R
E
G
I
Site 169
T1857
G
V
A
K
A
Y
D
T
V
R
E
G
I
L
D
Site 170
S1910
L
A
T
E
A
T
S
S
L
L
G
G
M
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation