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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C16orf84
Full Name:
Cytoplasmic tRNA 2-thiolation protein 2
Alias:
Chromosome 16 open reading frame 84; CP084; Cytosolic thiouridylase subunit 2; NCS2
Type:
Mass (Da):
56110
Number AA:
UniProt ID:
Q2VPK5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0034227
GO:0002098
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
C
Q
V
G
E
D
Y
G
E
P
A
P
E
E
Site 2
S23
P
P
P
A
P
R
P
S
R
E
Q
K
C
V
K
Site 3
Y55
R
D
C
F
K
A
F
Y
V
H
K
F
R
A
M
Site 4
S80
E
K
V
L
L
A
W
S
G
G
P
S
S
S
S
Site 5
S84
L
A
W
S
G
G
P
S
S
S
S
M
V
W
Q
Site 6
S85
A
W
S
G
G
P
S
S
S
S
M
V
W
Q
V
Site 7
S87
S
G
G
P
S
S
S
S
M
V
W
Q
V
L
E
Site 8
S122
E
G
A
A
C
G
Q
S
L
E
E
R
S
K
T
Site 9
T129
S
L
E
E
R
S
K
T
L
A
E
V
K
P
I
Site 10
S170
S
A
Q
E
L
V
G
S
E
G
A
Y
K
A
A
Site 11
S180
A
Y
K
A
A
V
D
S
F
L
Q
Q
Q
H
V
Site 12
T222
R
P
P
A
P
A
Q
T
E
A
L
S
Q
L
F
Site 13
S226
P
A
Q
T
E
A
L
S
Q
L
F
C
S
V
R
Site 14
S260
M
A
R
A
H
G
Y
S
K
V
M
T
G
D
S
Site 15
T264
H
G
Y
S
K
V
M
T
G
D
S
C
T
R
L
Site 16
S267
S
K
V
M
T
G
D
S
C
T
R
L
A
I
K
Site 17
S294
L
A
W
D
T
G
F
S
D
E
R
H
G
D
V
Site 18
T311
V
R
P
M
R
D
H
T
L
K
E
V
A
F
Y
Site 19
T334
V
F
T
P
A
V
D
T
K
A
P
E
K
A
S
Site 20
S341
T
K
A
P
E
K
A
S
I
H
R
L
M
E
A
Site 21
T360
L
Q
T
Q
F
P
S
T
V
S
T
V
Y
R
T
Site 22
T363
Q
F
P
S
T
V
S
T
V
Y
R
T
S
E
K
Site 23
S368
V
S
T
V
Y
R
T
S
E
K
L
V
K
G
P
Site 24
S384
D
G
P
A
A
G
D
S
G
P
R
C
L
L
C
Site 25
T410
A
T
A
F
G
A
Q
T
S
S
R
L
S
Q
M
Site 26
S411
T
A
F
G
A
Q
T
S
S
R
L
S
Q
M
Q
Site 27
S412
A
F
G
A
Q
T
S
S
R
L
S
Q
M
Q
S
Site 28
S415
A
Q
T
S
S
R
L
S
Q
M
Q
S
P
I
P
Site 29
S419
S
R
L
S
Q
M
Q
S
P
I
P
L
T
E
T
Site 30
T424
M
Q
S
P
I
P
L
T
E
T
R
T
P
P
G
Site 31
T426
S
P
I
P
L
T
E
T
R
T
P
P
G
P
C
Site 32
T428
I
P
L
T
E
T
R
T
P
P
G
P
C
C
S
Site 33
S435
T
P
P
G
P
C
C
S
P
G
V
G
W
A
Q
Site 34
Y464
C
I
E
E
Q
L
C
Y
S
C
R
V
N
M
K
Site 35
S475
V
N
M
K
D
L
P
S
L
D
P
L
P
P
Y
Site 36
S508
R
D
C
L
I
E
D
S
D
D
E
A
G
Q
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation