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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CORL2
Full Name:
SKI family transcriptional corepressor 2
Alias:
Functional Smad-suppressing element on chromosome 18;LBX1 corepressor 1-like protein;Ladybird homeobox corepressor 1-like protein
Type:
Mass (Da):
104235
Number AA:
1001
UniProt ID:
Q2VWA4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
P
N
D
I
L
L
A
S
P
S
S
A
F
Q
P
Site 2
S18
D
I
L
L
A
S
P
S
S
A
F
Q
P
D
T
Site 3
T25
S
S
A
F
Q
P
D
T
L
S
Q
P
R
P
G
Site 4
S27
A
F
Q
P
D
T
L
S
Q
P
R
P
G
H
A
Site 5
S76
N
T
L
L
K
N
F
S
Y
N
E
I
H
N
R
Site 6
Y77
T
L
L
K
N
F
S
Y
N
E
I
H
N
R
R
Site 7
S111
R
A
G
A
M
P
I
S
S
R
R
C
G
M
I
Site 8
T119
S
R
R
C
G
M
I
T
K
R
E
A
E
R
L
Site 9
S129
E
A
E
R
L
C
K
S
F
L
G
E
N
R
P
Site 10
Y164
G
S
F
I
P
A
R
Y
N
S
S
R
A
K
C
Site 11
S166
F
I
P
A
R
Y
N
S
S
R
A
K
C
I
K
Site 12
S190
P
N
K
F
I
F
H
S
H
R
T
P
D
A
K
Site 13
T193
F
I
F
H
S
H
R
T
P
D
A
K
Y
T
Q
Site 14
Y198
H
R
T
P
D
A
K
Y
T
Q
P
D
A
A
N
Site 15
S208
P
D
A
A
N
F
N
S
W
R
R
H
L
K
L
Site 16
T216
W
R
R
H
L
K
L
T
D
K
S
P
Q
D
E
Site 17
S219
H
L
K
L
T
D
K
S
P
Q
D
E
L
V
F
Site 18
S317
R
F
D
D
D
D
D
S
L
Q
E
A
A
V
V
Site 19
S379
A
G
A
K
G
P
R
S
Y
P
V
I
P
V
P
Site 20
Y380
G
A
K
G
P
R
S
Y
P
V
I
P
V
P
S
Site 21
S419
P
A
A
A
A
A
F
S
L
C
H
K
K
E
D
Site 22
T475
C
M
F
W
P
P
R
T
P
G
G
L
P
V
P
Site 23
T483
P
G
G
L
P
V
P
T
Y
L
Q
P
P
P
Q
Site 24
Y484
G
G
L
P
V
P
T
Y
L
Q
P
P
P
Q
P
Site 25
S493
Q
P
P
P
Q
P
P
S
A
L
G
C
A
L
G
Site 26
S522
E
P
G
G
A
A
G
S
A
E
A
A
P
P
P
Site 27
S542
V
V
A
N
G
P
G
S
G
P
P
P
P
A
G
Site 28
S560
S
R
D
A
L
F
E
S
P
P
G
G
S
G
G
Site 29
S570
G
G
S
G
G
D
C
S
A
G
S
T
P
P
A
Site 30
S573
G
G
D
C
S
A
G
S
T
P
P
A
D
S
V
Site 31
T574
G
D
C
S
A
G
S
T
P
P
A
D
S
V
A
Site 32
S597
A
G
S
G
P
A
G
S
R
V
P
A
P
H
H
Site 33
S617
G
R
K
A
G
G
G
S
Y
H
H
S
S
A
F
Site 34
Y618
R
K
A
G
G
G
S
Y
H
H
S
S
A
F
R
Site 35
S621
G
G
G
S
Y
H
H
S
S
A
F
R
P
V
G
Site 36
S622
G
G
S
Y
H
H
S
S
A
F
R
P
V
G
G
Site 37
S635
G
G
K
D
D
A
E
S
L
A
K
L
H
G
A
Site 38
S649
A
S
A
G
A
P
H
S
A
Q
T
H
P
H
H
Site 39
S674
H
H
P
P
Q
P
P
S
P
L
L
L
L
P
P
Site 40
S688
P
Q
P
D
E
P
G
S
E
R
H
H
P
A
P
Site 41
S718
P
H
H
R
G
L
L
S
P
G
G
T
S
C
C
Site 42
T722
G
L
L
S
P
G
G
T
S
C
C
Y
P
S
E
Site 43
Y726
P
G
G
T
S
C
C
Y
P
S
E
D
S
S
E
Site 44
S728
G
T
S
C
C
Y
P
S
E
D
S
S
E
D
E
Site 45
S732
C
Y
P
S
E
D
S
S
E
D
E
D
D
E
E
Site 46
T773
D
E
E
E
D
E
E
T
E
V
L
L
G
D
P
Site 47
S794
F
L
Q
G
R
G
P
S
E
K
G
S
S
R
D
Site 48
S798
R
G
P
S
E
K
G
S
S
R
D
R
A
P
A
Site 49
S799
G
P
S
E
K
G
S
S
R
D
R
A
P
A
V
Site 50
S816
A
F
P
L
G
L
N
S
S
R
L
L
Q
E
D
Site 51
S831
G
K
L
G
D
P
G
S
D
L
P
P
P
P
P
Site 52
S847
P
L
A
P
Q
K
A
S
G
G
G
S
S
S
P
Site 53
S851
Q
K
A
S
G
G
G
S
S
S
P
G
S
P
V
Site 54
S852
K
A
S
G
G
G
S
S
S
P
G
S
P
V
H
Site 55
S853
A
S
G
G
G
S
S
S
P
G
S
P
V
H
H
Site 56
S856
G
G
S
S
S
P
G
S
P
V
H
H
P
S
L
Site 57
S862
G
S
P
V
H
H
P
S
L
E
E
Q
P
S
Y
Site 58
S868
P
S
L
E
E
Q
P
S
Y
K
D
S
Q
K
T
Site 59
Y869
S
L
E
E
Q
P
S
Y
K
D
S
Q
K
T
K
Site 60
S872
E
Q
P
S
Y
K
D
S
Q
K
T
K
E
N
N
Site 61
S890
V
S
T
K
D
D
N
S
F
S
D
K
N
K
E
Site 62
S892
T
K
D
D
N
S
F
S
D
K
N
K
E
H
S
Site 63
S899
S
D
K
N
K
E
H
S
F
F
I
T
D
S
D
Site 64
T903
K
E
H
S
F
F
I
T
D
S
D
A
S
G
G
Site 65
S905
H
S
F
F
I
T
D
S
D
A
S
G
G
D
F
Site 66
S917
G
D
F
W
R
E
R
S
G
E
H
T
Q
E
T
Site 67
T921
R
E
R
S
G
E
H
T
Q
E
T
N
S
P
H
Site 68
T924
S
G
E
H
T
Q
E
T
N
S
P
H
S
L
K
Site 69
S926
E
H
T
Q
E
T
N
S
P
H
S
L
K
K
D
Site 70
S929
Q
E
T
N
S
P
H
S
L
K
K
D
V
E
N
Site 71
S968
Q
V
L
K
G
N
T
S
F
P
V
F
N
N
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation