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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LETM2
Full Name:
LETM1 domain-containing protein LETM2, mitochondrial
Alias:
LETM1 and EF-hand domain-containing protein 2;Leucine zipper-EF-hand-containing transmembrane protein 1-like
Type:
Mass (Da):
55921
Number AA:
491
UniProt ID:
Q2VYF4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
P
S
H
F
V
H
P
T
C
S
S
Y
S
P
S
Site 2
S30
H
P
T
C
S
S
Y
S
P
S
C
A
F
L
H
Site 3
T46
P
D
S
H
L
N
K
T
C
M
K
N
Y
E
S
Site 4
Y51
N
K
T
C
M
K
N
Y
E
S
K
K
Y
S
D
Site 5
S53
T
C
M
K
N
Y
E
S
K
K
Y
S
D
P
S
Site 6
Y56
K
N
Y
E
S
K
K
Y
S
D
P
S
Q
P
G
Site 7
S57
N
Y
E
S
K
K
Y
S
D
P
S
Q
P
G
N
Site 8
S60
S
K
K
Y
S
D
P
S
Q
P
G
N
T
V
L
Site 9
T65
D
P
S
Q
P
G
N
T
V
L
H
P
G
T
R
Site 10
T71
N
T
V
L
H
P
G
T
R
L
I
Q
K
L
H
Site 11
S104
T
K
H
P
Q
V
T
S
P
Q
A
T
K
E
T
Site 12
S121
E
I
K
E
G
K
Q
S
Y
R
Q
K
I
M
D
Site 13
Y132
K
I
M
D
E
L
K
Y
Y
Y
N
G
F
Y
L
Site 14
Y134
M
D
E
L
K
Y
Y
Y
N
G
F
Y
L
L
W
Site 15
Y138
K
Y
Y
Y
N
G
F
Y
L
L
W
I
D
A
K
Site 16
T171
E
R
R
R
L
L
R
T
C
V
D
F
F
R
L
Site 17
S207
L
F
P
E
M
L
P
S
T
F
E
S
E
S
K
Site 18
T208
F
P
E
M
L
P
S
T
F
E
S
E
S
K
K
Site 19
S211
M
L
P
S
T
F
E
S
E
S
K
K
E
E
K
Site 20
T238
K
F
L
Q
E
T
M
T
E
M
A
R
R
N
R
Site 21
S252
R
A
K
M
G
D
A
S
T
Q
L
S
S
Y
V
Site 22
T253
A
K
M
G
D
A
S
T
Q
L
S
S
Y
V
K
Site 23
S256
G
D
A
S
T
Q
L
S
S
Y
V
K
Q
V
Q
Site 24
S257
D
A
S
T
Q
L
S
S
Y
V
K
Q
V
Q
T
Site 25
Y258
A
S
T
Q
L
S
S
Y
V
K
Q
V
Q
T
G
Site 26
T270
Q
T
G
H
K
P
S
T
K
E
I
V
R
F
S
Site 27
S277
T
K
E
I
V
R
F
S
K
L
F
E
D
Q
L
Site 28
S322
Q
L
L
M
K
L
K
S
I
K
A
D
D
E
I
Site 29
S354
C
R
A
R
G
M
R
S
L
G
L
T
E
E
Q
Site 30
T358
G
M
R
S
L
G
L
T
E
E
Q
L
R
Q
Q
Site 31
T367
E
Q
L
R
Q
Q
L
T
E
W
Q
D
L
H
L
Site 32
S404
K
P
I
E
I
P
L
S
G
E
A
P
K
T
D
Site 33
T418
D
I
L
V
E
L
P
T
F
T
E
S
K
E
N
Site 34
T448
F
I
Q
P
P
P
V
T
S
S
P
I
T
P
S
Site 35
S449
I
Q
P
P
P
V
T
S
S
P
I
T
P
S
T
Site 36
S450
Q
P
P
P
V
T
S
S
P
I
T
P
S
T
P
Site 37
S455
T
S
S
P
I
T
P
S
T
P
I
S
L
P
K
Site 38
T456
S
S
P
I
T
P
S
T
P
I
S
L
P
K
G
Site 39
T466
S
L
P
K
G
P
I
T
S
S
E
E
P
T
L
Site 40
S468
P
K
G
P
I
T
S
S
E
E
P
T
L
Q
A
Site 41
T472
I
T
S
S
E
E
P
T
L
Q
A
K
S
Q
M
Site 42
S477
E
P
T
L
Q
A
K
S
Q
M
T
A
Q
N
S
Site 43
S484
S
Q
M
T
A
Q
N
S
K
A
S
S
K
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation