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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATHL1
Full Name:
Acid trehalase-like protein 1
Alias:
Type:
Mass (Da):
80655
Number AA:
737
UniProt ID:
Q32M88
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
D
A
G
E
D
P
T
T
F
A
A
H
S
L
P
Site 2
S15
P
T
T
F
A
A
H
S
L
P
S
D
P
R
L
Site 3
T39
G
T
R
V
F
H
D
T
L
H
V
S
G
V
Y
Site 4
Y46
T
L
H
V
S
G
V
Y
N
G
A
G
G
D
T
Site 5
T53
Y
N
G
A
G
G
D
T
H
R
A
M
L
P
S
Site 6
S60
T
H
R
A
M
L
P
S
P
L
N
V
R
L
E
Site 7
T77
A
G
M
G
E
Q
L
T
E
T
F
A
L
D
T
Site 8
T79
M
G
E
Q
L
T
E
T
F
A
L
D
T
N
T
Site 9
T84
T
E
T
F
A
L
D
T
N
T
G
S
F
L
H
Site 10
S88
A
L
D
T
N
T
G
S
F
L
H
T
L
E
G
Site 11
T92
N
T
G
S
F
L
H
T
L
E
G
P
R
F
R
Site 12
S101
E
G
P
R
F
R
A
S
Q
C
I
Y
A
H
R
Site 13
Y105
F
R
A
S
Q
C
I
Y
A
H
R
T
L
P
H
Site 14
S139
L
L
L
R
S
A
F
S
P
E
S
P
D
L
D
Site 15
S142
R
S
A
F
S
P
E
S
P
D
L
D
L
H
Q
Site 16
Y158
P
D
F
Q
G
A
R
Y
L
Y
G
H
T
L
T
Site 17
Y160
F
Q
G
A
R
Y
L
Y
G
H
T
L
T
P
E
Site 18
T163
A
R
Y
L
Y
G
H
T
L
T
P
E
Q
P
G
Site 19
T165
Y
L
Y
G
H
T
L
T
P
E
Q
P
G
G
P
Site 20
T181
Q
E
V
H
M
L
W
T
P
A
P
P
D
L
T
Site 21
T188
T
P
A
P
P
D
L
T
L
G
E
G
E
E
A
Site 22
T197
G
E
G
E
E
A
R
T
W
D
F
L
T
A
V
Site 23
T202
A
R
T
W
D
F
L
T
A
V
G
G
S
Q
A
Site 24
Y228
L
Q
A
R
G
A
L
Y
T
A
H
A
Q
A
W
Site 25
T229
Q
A
R
G
A
L
Y
T
A
H
A
Q
A
W
A
Site 26
Y275
P
Q
P
K
A
P
G
Y
I
C
H
G
L
S
P
Site 27
S281
G
Y
I
C
H
G
L
S
P
G
G
L
S
N
G
Site 28
S286
G
L
S
P
G
G
L
S
N
G
S
R
E
E
C
Site 29
S289
P
G
G
L
S
N
G
S
R
E
E
C
Y
W
G
Site 30
Y324
A
A
R
A
I
L
E
Y
R
I
R
T
L
D
G
Site 31
T328
I
L
E
Y
R
I
R
T
L
D
G
A
L
E
N
Site 32
S350
G
A
K
F
A
W
E
S
A
D
S
G
L
E
V
Site 33
S353
F
A
W
E
S
A
D
S
G
L
E
V
C
P
E
Site 34
Y363
E
V
C
P
E
D
I
Y
G
V
Q
E
V
H
V
Site 35
Y420
W
S
P
R
E
E
K
Y
H
L
R
G
V
M
S
Site 36
S427
Y
H
L
R
G
V
M
S
P
D
E
Y
H
S
G
Site 37
Y431
G
V
M
S
P
D
E
Y
H
S
G
V
N
N
S
Site 38
Y440
S
G
V
N
N
S
V
Y
T
N
V
L
V
Q
N
Site 39
Y491
F
H
P
E
F
D
G
Y
E
P
G
E
V
V
K
Site 40
S512
L
G
Y
P
V
P
F
S
L
S
P
D
V
R
R
Site 41
S514
Y
P
V
P
F
S
L
S
P
D
V
R
R
K
N
Site 42
Y525
R
R
K
N
L
E
I
Y
E
A
V
T
S
P
Q
Site 43
S530
E
I
Y
E
A
V
T
S
P
Q
G
P
A
M
T
Site 44
S561
A
R
G
L
L
D
R
S
F
A
N
M
A
E
P
Site 45
S637
Q
G
N
K
L
N
F
S
F
S
E
D
S
V
T
Site 46
S639
N
K
L
N
F
S
F
S
E
D
S
V
T
V
E
Site 47
S642
N
F
S
F
S
E
D
S
V
T
V
E
V
T
A
Site 48
T644
S
F
S
E
D
S
V
T
V
E
V
T
A
R
A
Site 49
S665
L
E
A
E
L
W
P
S
Q
S
R
L
S
L
L
Site 50
S667
A
E
L
W
P
S
Q
S
R
L
S
L
L
P
G
Site 51
S670
W
P
S
Q
S
R
L
S
L
L
P
G
H
K
V
Site 52
S678
L
L
P
G
H
K
V
S
F
P
R
S
A
G
R
Site 53
S682
H
K
V
S
F
P
R
S
A
G
R
I
Q
M
S
Site 54
S689
S
A
G
R
I
Q
M
S
P
P
K
L
P
G
S
Site 55
S696
S
P
P
K
L
P
G
S
S
S
S
E
F
P
G
Site 56
S697
P
P
K
L
P
G
S
S
S
S
E
F
P
G
R
Site 57
S698
P
K
L
P
G
S
S
S
S
E
F
P
G
R
T
Site 58
S699
K
L
P
G
S
S
S
S
E
F
P
G
R
T
F
Site 59
T705
S
S
E
F
P
G
R
T
F
S
D
V
R
D
P
Site 60
S707
E
F
P
G
R
T
F
S
D
V
R
D
P
L
Q
Site 61
S715
D
V
R
D
P
L
Q
S
P
L
W
V
T
L
G
Site 62
T720
L
Q
S
P
L
W
V
T
L
G
S
S
S
P
T
Site 63
S723
P
L
W
V
T
L
G
S
S
S
P
T
E
S
L
Site 64
T727
T
L
G
S
S
S
P
T
E
S
L
T
V
D
P
Site 65
S729
G
S
S
S
P
T
E
S
L
T
V
D
P
A
S
Site 66
T731
S
S
P
T
E
S
L
T
V
D
P
A
S
E
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation