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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRFIP1
Full Name:
Leucine-rich repeat flightless-interacting protein 1
Alias:
FLAP-1; FLIIAP1; GC-binding factor 2; GCF2; GCF-2; HUFI-1; Leucine rich repeat (in FLII) interacting protein 1; Leucine-rich repeat flightless-interacting protein 1: LRR FLII-interacting protein 1: TAR RNA-interacting protein: GC-binding factor 2: Leucine-rich repeat flightless-interacting protein 1: LRR FLII-interacting protein 1: TAR RNA-interacting protein: GC-binding factor 2: Leucine-rich repeat flightless-interacting protein 1: LRR FLII-interacting protein 1: TAR RNA-interacting protein: GC-binding factor 2: LRRFIP1 protein: Putative uncharacterized protein tmplocus7; LRRF1; TAR RNA-interacting protein; TRIP
Type:
RNA binding protein
Mass (Da):
89253
Number AA:
808
UniProt ID:
Q32MZ4
International Prot ID:
IPI00006207
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003725
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016481
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
S
R
E
I
D
C
L
S
P
E
A
Q
K
L
A
Site 2
S54
R
Q
Q
K
E
E
D
S
E
R
Y
S
R
R
S
Site 3
Y57
K
E
E
D
S
E
R
Y
S
R
R
S
R
R
N
Site 4
S58
E
E
D
S
E
R
Y
S
R
R
S
R
R
N
T
Site 5
S61
S
E
R
Y
S
R
R
S
R
R
N
T
S
A
S
Site 6
T65
S
R
R
S
R
R
N
T
S
A
S
D
E
D
E
Site 7
S66
R
R
S
R
R
N
T
S
A
S
D
E
D
E
R
Site 8
S68
S
R
R
N
T
S
A
S
D
E
D
E
R
M
S
Site 9
S75
S
D
E
D
E
R
M
S
V
G
S
R
G
S
L
Site 10
S78
D
E
R
M
S
V
G
S
R
G
S
L
R
V
E
Site 11
S81
M
S
V
G
S
R
G
S
L
R
V
E
E
R
P
Site 12
T93
E
R
P
E
K
D
F
T
E
K
G
S
R
N
M
Site 13
S104
S
R
N
M
P
G
L
S
A
A
T
L
A
S
L
Site 14
T107
M
P
G
L
S
A
A
T
L
A
S
L
G
G
T
Site 15
S110
L
S
A
A
T
L
A
S
L
G
G
T
S
S
R
Site 16
T114
T
L
A
S
L
G
G
T
S
S
R
R
G
S
G
Site 17
S115
L
A
S
L
G
G
T
S
S
R
R
G
S
G
D
Site 18
S116
A
S
L
G
G
T
S
S
R
R
G
S
G
D
T
Site 19
S120
G
T
S
S
R
R
G
S
G
D
T
S
I
S
I
Site 20
T123
S
R
R
G
S
G
D
T
S
I
S
I
D
T
E
Site 21
S124
R
R
G
S
G
D
T
S
I
S
I
D
T
E
A
Site 22
S126
G
S
G
D
T
S
I
S
I
D
T
E
A
S
I
Site 23
S132
I
S
I
D
T
E
A
S
I
R
E
I
K
E
L
Site 24
Y153
I
Q
D
V
E
G
K
Y
M
Q
G
L
K
E
M
Site 25
S163
G
L
K
E
M
K
D
S
L
A
E
V
E
E
K
Site 26
Y190
N
E
K
T
N
F
M
Y
Q
V
D
T
L
K
D
Site 27
T194
N
F
M
Y
Q
V
D
T
L
K
D
M
L
L
E
Site 28
Y213
L
A
E
S
R
R
Q
Y
E
E
K
N
K
E
F
Site 29
T268
T
N
G
E
T
S
D
T
L
N
N
V
G
Y
Q
Site 30
Y274
D
T
L
N
N
V
G
Y
Q
G
P
T
K
M
T
Site 31
S290
E
E
L
N
A
L
K
S
T
G
D
G
T
L
G
Site 32
T295
L
K
S
T
G
D
G
T
L
G
R
A
S
E
V
Site 33
S300
D
G
T
L
G
R
A
S
E
V
E
V
K
N
E
Site 34
T330
K
E
Q
H
T
E
D
T
V
K
D
C
V
D
I
Site 35
S351
E
N
T
E
D
Q
K
S
S
E
D
T
A
P
F
Site 36
T355
D
Q
K
S
S
E
D
T
A
P
F
L
G
T
L
Site 37
Y367
G
T
L
A
G
A
T
Y
E
E
Q
V
Q
S
Q
Site 38
S373
T
Y
E
E
Q
V
Q
S
Q
I
L
E
S
S
S
Site 39
S380
S
Q
I
L
E
S
S
S
L
P
E
N
T
V
Q
Site 40
T385
S
S
S
L
P
E
N
T
V
Q
V
E
S
N
E
Site 41
T401
M
G
A
P
D
D
R
T
R
T
P
L
E
P
S
Site 42
T403
A
P
D
D
R
T
R
T
P
L
E
P
S
N
C
Site 43
S408
T
R
T
P
L
E
P
S
N
C
W
S
D
L
D
Site 44
S412
L
E
P
S
N
C
W
S
D
L
D
G
G
N
H
Site 45
T429
N
V
G
E
A
A
V
T
Q
V
E
E
Q
A
G
Site 46
T437
Q
V
E
E
Q
A
G
T
V
A
S
C
P
L
G
Site 47
S440
E
Q
A
G
T
V
A
S
C
P
L
G
H
S
D
Site 48
S446
A
S
C
P
L
G
H
S
D
D
T
V
Y
H
D
Site 49
T449
P
L
G
H
S
D
D
T
V
Y
H
D
D
K
C
Site 50
Y451
G
H
S
D
D
T
V
Y
H
D
D
K
C
M
V
Site 51
S467
V
P
Q
E
L
E
T
S
T
G
H
S
L
E
K
Site 52
S471
L
E
T
S
T
G
H
S
L
E
K
E
F
T
N
Site 53
T477
H
S
L
E
K
E
F
T
N
Q
E
A
A
E
P
Site 54
S491
P
K
E
V
P
A
H
S
T
E
V
G
R
D
H
Site 55
T516
R
D
E
K
P
I
K
T
E
V
P
G
S
P
A
Site 56
S521
I
K
T
E
V
P
G
S
P
A
G
T
E
G
N
Site 57
T525
V
P
G
S
P
A
G
T
E
G
N
C
Q
E
A
Site 58
T537
Q
E
A
T
G
P
S
T
V
D
T
Q
N
E
P
Site 59
T540
T
G
P
S
T
V
D
T
Q
N
E
P
L
D
M
Site 60
S555
K
E
P
D
E
E
K
S
D
Q
Q
G
E
A
L
Site 61
S564
Q
Q
G
E
A
L
D
S
S
Q
K
K
T
K
N
Site 62
S565
Q
G
E
A
L
D
S
S
Q
K
K
T
K
N
K
Site 63
T569
L
D
S
S
Q
K
K
T
K
N
K
K
K
K
N
Site 64
S581
K
K
N
K
K
K
K
S
P
V
P
V
E
T
L
Site 65
T596
K
D
V
K
K
E
L
T
Y
Q
N
T
D
L
S
Site 66
Y597
D
V
K
K
E
L
T
Y
Q
N
T
D
L
S
E
Site 67
S603
T
Y
Q
N
T
D
L
S
E
I
K
E
E
E
Q
Site 68
S613
K
E
E
E
Q
V
K
S
T
D
R
K
S
A
V
Site 69
T614
E
E
E
Q
V
K
S
T
D
R
K
S
A
V
E
Site 70
S618
V
K
S
T
D
R
K
S
A
V
E
A
Q
N
E
Site 71
S638
K
Q
K
I
A
A
E
S
S
E
N
V
D
C
P
Site 72
T676
E
V
L
A
D
G
D
T
L
D
F
E
D
D
T
Site 73
T683
T
L
D
F
E
D
D
T
V
Q
S
S
G
P
R
Site 74
S686
F
E
D
D
T
V
Q
S
S
G
P
R
A
G
G
Site 75
S687
E
D
D
T
V
Q
S
S
G
P
R
A
G
G
E
Site 76
T711
N
A
K
I
D
G
A
T
Q
S
S
P
A
E
P
Site 77
S713
K
I
D
G
A
T
Q
S
S
P
A
E
P
K
S
Site 78
S714
I
D
G
A
T
Q
S
S
P
A
E
P
K
S
E
Site 79
S720
S
S
P
A
E
P
K
S
E
D
A
D
R
C
T
Site 80
T727
S
E
D
A
D
R
C
T
L
P
E
H
E
S
P
Site 81
S733
C
T
L
P
E
H
E
S
P
S
Q
D
I
S
D
Site 82
S735
L
P
E
H
E
S
P
S
Q
D
I
S
D
A
C
Site 83
S739
E
S
P
S
Q
D
I
S
D
A
C
E
A
E
S
Site 84
T747
D
A
C
E
A
E
S
T
E
R
C
E
M
S
E
Site 85
S753
S
T
E
R
C
E
M
S
E
H
P
S
Q
T
V
Site 86
S757
C
E
M
S
E
H
P
S
Q
T
V
R
K
A
L
Site 87
T759
M
S
E
H
P
S
Q
T
V
R
K
A
L
D
S
Site 88
S766
T
V
R
K
A
L
D
S
N
S
L
E
N
D
D
Site 89
S768
R
K
A
L
D
S
N
S
L
E
N
D
D
L
S
Site 90
S775
S
L
E
N
D
D
L
S
A
P
G
R
E
P
G
Site 91
S788
P
G
H
F
N
P
E
S
R
E
D
T
R
G
G
Site 92
T792
N
P
E
S
R
E
D
T
R
G
G
N
E
K
G
Site 93
S801
G
G
N
E
K
G
K
S
K
E
D
C
T
M
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation