KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
EML3
Full Name:
Echinoderm microtubule-associated protein-like 3
Alias:
Echinoderm microtubule associated like 3; Echinoderm microtubule associated protein like 3; ELP95; EMAL3; EMAP-3; FLJ35827
Type:
Microtubule, Cytoplasm protein
Mass (Da):
95197
Number AA:
896
UniProt ID:
Q32P44
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
P
A
R
E
A
L
Q
S
L
S
Q
R
L
R
V
Site 2
S20
R
E
A
L
Q
S
L
S
Q
R
L
R
V
Q
E
Site 3
S51
L
R
L
Q
V
P
P
S
S
L
Q
G
S
G
T
Site 4
S52
R
L
Q
V
P
P
S
S
L
Q
G
S
G
T
P
Site 5
S56
P
P
S
S
L
Q
G
S
G
T
P
A
P
P
G
Site 6
T58
S
S
L
Q
G
S
G
T
P
A
P
P
G
D
S
Site 7
S65
T
P
A
P
P
G
D
S
L
A
A
P
P
G
L
Site 8
T77
P
G
L
P
P
T
C
T
P
S
L
V
S
R
G
Site 9
S79
L
P
P
T
C
T
P
S
L
V
S
R
G
T
Q
Site 10
T85
P
S
L
V
S
R
G
T
Q
T
E
T
E
V
E
Site 11
S95
E
T
E
V
E
L
K
S
S
P
G
P
P
G
L
Site 12
S96
T
E
V
E
L
K
S
S
P
G
P
P
G
L
S
Site 13
S103
S
P
G
P
P
G
L
S
N
G
P
P
A
P
Q
Site 14
S113
P
P
A
P
Q
G
A
S
E
E
P
S
G
T
Q
Site 15
S117
Q
G
A
S
E
E
P
S
G
T
Q
S
E
G
G
Site 16
T119
A
S
E
E
P
S
G
T
Q
S
E
G
G
G
S
Site 17
S121
E
E
P
S
G
T
Q
S
E
G
G
G
S
S
S
Site 18
S126
T
Q
S
E
G
G
G
S
S
S
S
G
A
G
S
Site 19
S127
Q
S
E
G
G
G
S
S
S
S
G
A
G
S
P
Site 20
S128
S
E
G
G
G
S
S
S
S
G
A
G
S
P
G
Site 21
S129
E
G
G
G
S
S
S
S
G
A
G
S
P
G
P
Site 22
S133
S
S
S
S
G
A
G
S
P
G
P
P
G
I
L
Site 23
T151
Q
P
P
Q
R
A
D
T
P
R
R
N
S
S
S
Site 24
S156
A
D
T
P
R
R
N
S
S
S
S
S
S
P
S
Site 25
S157
D
T
P
R
R
N
S
S
S
S
S
S
P
S
E
Site 26
S158
T
P
R
R
N
S
S
S
S
S
S
P
S
E
R
Site 27
S159
P
R
R
N
S
S
S
S
S
S
P
S
E
R
P
Site 28
S160
R
R
N
S
S
S
S
S
S
P
S
E
R
P
R
Site 29
S161
R
N
S
S
S
S
S
S
P
S
E
R
P
R
Q
Site 30
S163
S
S
S
S
S
S
P
S
E
R
P
R
Q
K
L
Site 31
S171
E
R
P
R
Q
K
L
S
R
K
A
I
S
S
A
Site 32
S176
K
L
S
R
K
A
I
S
S
A
N
L
L
V
R
Site 33
S177
L
S
R
K
A
I
S
S
A
N
L
L
V
R
S
Site 34
S184
S
A
N
L
L
V
R
S
G
S
T
E
S
R
G
Site 35
S186
N
L
L
V
R
S
G
S
T
E
S
R
G
G
K
Site 36
S197
R
G
G
K
D
P
L
S
S
P
G
G
P
G
S
Site 37
S198
G
G
K
D
P
L
S
S
P
G
G
P
G
S
R
Site 38
S204
S
S
P
G
G
P
G
S
R
R
S
N
Y
N
L
Site 39
S207
G
G
P
G
S
R
R
S
N
Y
N
L
E
G
I
Site 40
Y209
P
G
S
R
R
S
N
Y
N
L
E
G
I
S
V
Site 41
S215
N
Y
N
L
E
G
I
S
V
K
M
F
L
R
G
Site 42
Y228
R
G
R
P
I
T
M
Y
I
P
S
G
I
R
S
Site 43
S231
P
I
T
M
Y
I
P
S
G
I
R
S
L
E
E
Site 44
S235
Y
I
P
S
G
I
R
S
L
E
E
L
P
S
G
Site 45
S241
R
S
L
E
E
L
P
S
G
P
P
P
E
T
L
Site 46
T247
P
S
G
P
P
P
E
T
L
S
L
D
W
V
Y
Site 47
S249
G
P
P
P
E
T
L
S
L
D
W
V
Y
G
Y
Site 48
Y254
T
L
S
L
D
W
V
Y
G
Y
R
G
R
D
S
Site 49
Y256
S
L
D
W
V
Y
G
Y
R
G
R
D
S
R
S
Site 50
S261
Y
G
Y
R
G
R
D
S
R
S
N
L
F
V
L
Site 51
S263
Y
R
G
R
D
S
R
S
N
L
F
V
L
R
S
Site 52
Y301
G
G
G
G
Q
R
H
Y
R
G
H
T
D
C
V
Site 53
T305
Q
R
H
Y
R
G
H
T
D
C
V
R
C
L
A
Site 54
S322
P
D
G
V
R
V
A
S
G
Q
T
A
G
V
D
Site 55
T346
V
H
I
W
D
S
E
T
L
L
K
L
Q
E
I
Site 56
S403
M
K
L
A
E
I
K
S
T
N
D
S
V
L
A
Site 57
S407
E
I
K
S
T
N
D
S
V
L
A
V
G
F
N
Site 58
S418
V
G
F
N
P
R
D
S
S
C
I
V
T
S
G
Site 59
S419
G
F
N
P
R
D
S
S
C
I
V
T
S
G
K
Site 60
T423
R
D
S
S
C
I
V
T
S
G
K
S
H
V
H
Site 61
S424
D
S
S
C
I
V
T
S
G
K
S
H
V
H
F
Site 62
T445
V
G
V
P
G
N
G
T
L
T
R
K
Q
G
V
Site 63
Y456
K
Q
G
V
F
G
K
Y
K
K
P
K
F
I
P
Site 64
T475
L
P
D
G
D
I
L
T
G
D
S
E
G
N
I
Site 65
T484
D
S
E
G
N
I
L
T
W
G
R
S
P
S
D
Site 66
S488
N
I
L
T
W
G
R
S
P
S
D
S
K
T
P
Site 67
S490
L
T
W
G
R
S
P
S
D
S
K
T
P
G
R
Site 68
S492
W
G
R
S
P
S
D
S
K
T
P
G
R
G
G
Site 69
T494
R
S
P
S
D
S
K
T
P
G
R
G
G
A
K
Site 70
Y504
R
G
G
A
K
E
T
Y
G
I
V
A
Q
A
H
Site 71
T527
L
C
L
R
R
D
G
T
V
L
S
G
G
G
R
Site 72
S530
R
R
D
G
T
V
L
S
G
G
G
R
D
R
R
Site 73
S590
G
D
L
A
Q
G
F
S
P
V
I
Q
G
H
T
Site 74
T614
P
S
Q
N
R
F
L
T
C
G
H
D
R
Q
L
Site 75
T667
G
R
W
L
V
L
D
T
E
T
R
E
I
V
S
Site 76
S684
I
D
G
N
E
Q
L
S
V
V
R
Y
S
P
D
Site 77
Y688
E
Q
L
S
V
V
R
Y
S
P
D
G
L
Y
L
Site 78
Y694
R
Y
S
P
D
G
L
Y
L
A
I
G
S
H
D
Site 79
Y705
G
S
H
D
N
V
I
Y
I
Y
S
V
S
S
D
Site 80
Y707
H
D
N
V
I
Y
I
Y
S
V
S
S
D
G
A
Site 81
S708
D
N
V
I
Y
I
Y
S
V
S
S
D
G
A
K
Site 82
S711
I
Y
I
Y
S
V
S
S
D
G
A
K
S
S
R
Site 83
S716
V
S
S
D
G
A
K
S
S
R
F
G
R
C
M
Site 84
S717
S
S
D
G
A
K
S
S
R
F
G
R
C
M
G
Site 85
T730
M
G
H
S
S
F
I
T
H
L
D
W
S
K
D
Site 86
S743
K
D
G
N
F
I
M
S
N
S
G
D
Y
E
I
Site 87
Y748
I
M
S
N
S
G
D
Y
E
I
L
Y
W
D
V
Site 88
Y752
S
G
D
Y
E
I
L
Y
W
D
V
A
G
G
C
Site 89
S768
Q
L
K
N
R
Y
E
S
R
D
R
E
W
A
T
Site 90
Y776
R
D
R
E
W
A
T
Y
T
C
V
L
G
F
H
Site 91
S792
Y
G
V
W
P
D
G
S
D
G
T
D
I
N
S
Site 92
T795
W
P
D
G
S
D
G
T
D
I
N
S
L
C
R
Site 93
S799
S
D
G
T
D
I
N
S
L
C
R
S
H
N
E
Site 94
S803
D
I
N
S
L
C
R
S
H
N
E
R
V
V
A
Site 95
Y823
C
K
V
H
L
F
Q
Y
P
C
A
R
A
K
A
Site 96
S832
C
A
R
A
K
A
P
S
R
M
Y
G
G
H
G
Site 97
Y835
A
K
A
P
S
R
M
Y
G
G
H
G
S
H
V
Site 98
S840
R
M
Y
G
G
H
G
S
H
V
T
S
V
R
F
Site 99
T843
G
G
H
G
S
H
V
T
S
V
R
F
T
H
D
Site 100
S844
G
H
G
S
H
V
T
S
V
R
F
T
H
D
D
Site 101
T848
H
V
T
S
V
R
F
T
H
D
D
S
H
L
V
Site 102
S852
V
R
F
T
H
D
D
S
H
L
V
S
L
G
G
Site 103
S856
H
D
D
S
H
L
V
S
L
G
G
K
D
A
S
Site 104
T881
G
A
G
P
A
P
A
T
P
S
R
T
P
S
L
Site 105
S883
G
P
A
P
A
T
P
S
R
T
P
S
L
S
P
Site 106
T885
A
P
A
T
P
S
R
T
P
S
L
S
P
A
S
Site 107
S887
A
T
P
S
R
T
P
S
L
S
P
A
S
S
L
Site 108
S889
P
S
R
T
P
S
L
S
P
A
S
S
L
D
V
Site 109
S892
T
P
S
L
S
P
A
S
S
L
D
V
_
_
_
Site 110
S893
P
S
L
S
P
A
S
S
L
D
V
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation