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Updated November 2019
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Protein Info
Short Name:
BEAN
Full Name:
Protein BEAN
Alias:
Brain-expressed protein associating with Nedd4 homolog
Type:
Mass (Da):
28626
Number AA:
259
UniProt ID:
Q3B7T3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
R
P
C
P
L
A
R
Y
N
R
T
S
Y
F
Y
Site 2
S16
L
A
R
Y
N
R
T
S
Y
F
Y
P
T
F
S
Site 3
Y17
A
R
Y
N
R
T
S
Y
F
Y
P
T
F
S
E
Site 4
Y19
Y
N
R
T
S
Y
F
Y
P
T
F
S
E
S
S
Site 5
T21
R
T
S
Y
F
Y
P
T
F
S
E
S
S
E
H
Site 6
S23
S
Y
F
Y
P
T
F
S
E
S
S
E
H
S
H
Site 7
S25
F
Y
P
T
F
S
E
S
S
E
H
S
H
L
L
Site 8
S26
Y
P
T
F
S
E
S
S
E
H
S
H
L
L
V
Site 9
S29
F
S
E
S
S
E
H
S
H
L
L
V
S
P
V
Site 10
Y92
R
R
R
R
H
R
E
Y
E
H
G
Y
V
S
D
Site 11
Y96
H
R
E
Y
E
H
G
Y
V
S
D
E
H
T
Y
Site 12
S98
E
Y
E
H
G
Y
V
S
D
E
H
T
Y
S
R
Site 13
T102
G
Y
V
S
D
E
H
T
Y
S
R
S
S
R
R
Site 14
Y103
Y
V
S
D
E
H
T
Y
S
R
S
S
R
R
M
Site 15
S104
V
S
D
E
H
T
Y
S
R
S
S
R
R
M
R
Site 16
S106
D
E
H
T
Y
S
R
S
S
R
R
M
R
Y
A
Site 17
S107
E
H
T
Y
S
R
S
S
R
R
M
R
Y
A
C
Site 18
Y112
R
S
S
R
R
M
R
Y
A
C
S
S
S
E
D
Site 19
S115
R
R
M
R
Y
A
C
S
S
S
E
D
W
P
P
Site 20
S116
R
M
R
Y
A
C
S
S
S
E
D
W
P
P
P
Site 21
S117
M
R
Y
A
C
S
S
S
E
D
W
P
P
P
L
Site 22
S128
P
P
P
L
D
I
S
S
D
G
D
V
D
A
T
Site 23
T135
S
D
G
D
V
D
A
T
V
L
R
E
L
Y
P
Site 24
Y141
A
T
V
L
R
E
L
Y
P
D
S
P
P
G
Y
Site 25
S144
L
R
E
L
Y
P
D
S
P
P
G
Y
E
E
C
Site 26
Y148
Y
P
D
S
P
P
G
Y
E
E
C
V
G
P
G
Site 27
Y160
G
P
G
A
T
Q
L
Y
V
P
T
D
A
P
P
Site 28
T163
A
T
Q
L
Y
V
P
T
D
A
P
P
P
Y
S
Site 29
Y169
P
T
D
A
P
P
P
Y
S
L
T
D
S
C
P
Site 30
S170
T
D
A
P
P
P
Y
S
L
T
D
S
C
P
T
Site 31
T172
A
P
P
P
Y
S
L
T
D
S
C
P
T
L
D
Site 32
S174
P
P
Y
S
L
T
D
S
C
P
T
L
D
G
T
Site 33
T177
S
L
T
D
S
C
P
T
L
D
G
T
S
D
S
Site 34
T181
S
C
P
T
L
D
G
T
S
D
S
G
S
G
H
Site 35
S182
C
P
T
L
D
G
T
S
D
S
G
S
G
H
S
Site 36
S184
T
L
D
G
T
S
D
S
G
S
G
H
S
P
G
Site 37
S186
D
G
T
S
D
S
G
S
G
H
S
P
G
R
H
Site 38
S189
S
D
S
G
S
G
H
S
P
G
R
H
Q
Q
E
Site 39
T199
R
H
Q
Q
E
Q
R
T
P
A
Q
G
G
L
H
Site 40
T207
P
A
Q
G
G
L
H
T
V
S
M
D
T
L
P
Site 41
S209
Q
G
G
L
H
T
V
S
M
D
T
L
P
P
Y
Site 42
S241
P
D
P
G
P
R
G
S
Q
G
S
P
T
P
T
Site 43
S244
G
P
R
G
S
Q
G
S
P
T
P
T
R
A
P
Site 44
T246
R
G
S
Q
G
S
P
T
P
T
R
A
P
A
S
Site 45
T248
S
Q
G
S
P
T
P
T
R
A
P
A
S
G
P
Site 46
S253
T
P
T
R
A
P
A
S
G
P
E
R
I
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation