PhosphoNET

           
Protein Info 
   
Short Name:  PROX2
Full Name:  Prospero homeobox protein 2
Alias:  Homeobox prospero-like protein PROX2
Type: 
Mass (Da):  65586
Number AA:  592
UniProt ID:  Q3B8N5
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9DPNSILLSPQPQICS
Site 2S28ACTEGERSSSPPELD
Site 3S29CTEGERSSSPPELDR
Site 4S30TEGERSSSPPELDRD
Site 5S38PPELDRDSPFPWSQV
Site 6S43RDSPFPWSQVPSSSP
Site 7S47FPWSQVPSSSPTDPE
Site 8S48PWSQVPSSSPTDPEW
Site 9S49WSQVPSSSPTDPEWF
Site 10T51QVPSSSPTDPEWFGD
Site 11S92GNAQAGVSPRCPKKA
Site 12T110KRKQNLPTPQGLLMP
Site 13T159QAAKPRDTAQGPGGC
Site 14T168QGPGGCGTGKGPLSA
Site 15S174GTGKGPLSAKQGNGC
Site 16S197GDHQQGTSKDLSGAE
Site 17S201QGTSKDLSGAEKHQE
Site 18S209GAEKHQESEKPSFLP
Site 19S213HQESEKPSFLPSGAP
Site 20S217EKPSFLPSGAPASLE
Site 21S222LPSGAPASLEILRKE
Site 22T231EILRKELTRAVSQAV
Site 23T254LDPPGHLTQLGRSFQ
Site 24S259HLTQLGRSFQGQVAE
Site 25S269GQVAEGRSEPSPPVG
Site 26S272AEGRSEPSPPVGGAC
Site 27S311SLAKRLDSPRYPIPP
Site 28Y314KRLDSPRYPIPPRMT
Site 29T321YPIPPRMTPKPCQDP
Site 30T335PPANFPLTAPSHIQE
Site 31S347IQENQILSQLLGHRY
Site 32Y354SQLLGHRYNNGHWSS
Site 33S360RYNNGHWSSSPPQDS
Site 34S361YNNGHWSSSPPQDSS
Site 35S362NNGHWSSSPPQDSSS
Site 36S367SSSPPQDSSSQRHPS
Site 37S368SSPPQDSSSQRHPSS
Site 38S369SPPQDSSSQRHPSSE
Site 39S374SSSQRHPSSEPALRP
Site 40S375SSQRHPSSEPALRPW
Site 41T384PALRPWRTTKPQPLV
Site 42T385ALRPWRTTKPQPLVL
Site 43S393KPQPLVLSQQQCPLP
Site 44S403QCPLPFTSAHLESLP
Site 45S414ESLPLLPSVKMEQRG
Site 46S437PFSLVHISEGLNPGH
Site 47S459FFFTRYPSSNLLKVY
Site 48S460FFTRYPSSNLLKVYF
Site 49Y466SSNLLKVYFPDVQFN
Site 50Y491FSNFREFYYIQMEKS
Site 51Y492SNFREFYYIQMEKSA
Site 52S557QEFFRAVSAGRDSDP
Site 53S562AVSAGRDSDPSWKKP
Site 54S565AGRDSDPSWKKPIYK
Site 55Y571PSWKKPIYKIISKLD
Site 56S575KPIYKIISKLDSDIP
Site 57S579KIISKLDSDIPEIFK
Site 58S587DIPEIFKSSSYPQ__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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